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TLE3 [nucleoplasm]
Stable Identifier
R-HSA-3322363
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Icon
Locations in the PathwayBrowser for interactor UniProt:P0DTD1-PRO_0000449630 REP
Expand all
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Estrogen-dependent gene expression (Homo sapiens)
ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Homo sapiens)
TLE3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q04726 TLE3
Gene Names
TLE3, KIAA1547
Chain
chain:1-772
Reference Genes
COSMIC (genes):TLE3 TLE3
dbSNP Gene:7090 TLE3
ENSEMBL:ENSG00000140332 TLE3
Participates
as a component of
ESR1:ESTG:PGR:P4:FOXA1:GATA3:TLE3:NRIP:EP300 [nucleoplasm] (Homo sapiens)
TLE3 tetramer [nucleoplasm] (Homo sapiens)
as an input of
ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Homo sapiens)
as a member of
TLE [nucleoplasm] (Homo sapiens)
Other forms of this molecule
Ub-TLE3 [nucleoplasm]
Inferred To
TLE3 [nucleoplasm]
(Bos taurus)
TLE3 [nucleoplasm]
(Canis familiaris)
TLE3 [nucleoplasm]
(Gallus gallus)
TLE3 [nucleoplasm]
(Sus scrofa)
gro [nucleoplasm]
(Drosophila melanogaster)
unc-37 [nucleoplasm]
(Caenorhabditis elegans)
tle3b [nucleoplasm]
(Danio rerio)
Tle3 [nucleoplasm]
(Mus musculus)
Tle3 [nucleoplasm]
(Rattus norvegicus)
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9C009 FOXQ1
0.569
4
UniProt:Q05925 HME1
0.569
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.564
2
UniProt:Q04725 TLE2
2
Ub-TLE2 [nucleoplasm]
(R-HSA-3322370)
TLE2 [nucleoplasm]
(R-HSA-212354)
0.527
3
UniProt:P0DTD1-PRO_0000449630 REP
0.527
2
UniProt:Q12952 FOXL1
0.483
2
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