L-selenoC49-GPX1 [mitochondrial matrix]

Stable Identifier
R-HSA-3322994
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
GPX1, glutathione peroxidase monomer, GSHC_HUMAN, Glutathione peroxidase 1 , GSHPx-1, Cellular glutathione peroxidase
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
10833429 Mitochondrial GPx1 decreases induced but not basal oxidative damage to mtDNA in T47D cells

Mirault, ME, Petrov, P, Carrier, C, Legault, J, Renard, P, Remacle, J

Biochem. Biophys. Res. Commun. 2000
19228881 Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents

Muessig, E, Ullrich, V, Kienhöfer, J, Weber, K, Häussler, DJ, Ruckelshausen, F, Bachschmid, MM, Bürkle, A, Pimentel, D

FASEB J. 2009
23371551 Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging

Rhee, HW, Udeshi, ND, Ting, AY, Mootha, VK, Martell, JD, Zou, P, Carr, SA

Science 2013
External Reference Information
External Reference
UniProt:P07203 GPX1
Gene Names
GPX1
Chain
chain:1-203
Reference Genes
BioGPS Gene:2876 GPX1
COSMIC (genes):GPX1 GPX1
CTD Gene:2876 GPX1
dbSNP Gene:2876 GPX1
ENSEMBL:ENSG00000233276 GPX1
ENSEMBL:ENSG00000233276.9 GPX1
HGNC:4553 GPX1
KEGG Gene (Homo sapiens):2876 GPX1
Monarch:2876 GPX1
NCBI Gene:2876 GPX1
OMIM:138320 GPX1
UCSC:P07203 GPX1
Reference Transcript
Other Identifiers
11725346_x_at
11757455_x_at
16954048
200736_PM_s_at
200736_s_at
2674230
2674231
2674232
2674233
2674234
2674235
2674236
2674237
2674238
2674239
2674240
2674241
2876
37033_s_at
4000050
4000052
4000056
4000064
8087405
8180346
A_23_P250671
A_33_P3239849
GE80927
GO:0000302
GO:0001659
GO:0001885
GO:0002376
GO:0002862
GO:0003013
GO:0003824
GO:0004601
GO:0004602
GO:0005737
GO:0005739
GO:0005759
GO:0005829
GO:0006325
GO:0006575
GO:0006629
GO:0006641
GO:0006749
GO:0006790
GO:0006915
GO:0006954
GO:0006979
GO:0007005
GO:0007605
GO:0008631
GO:0009410
GO:0009609
GO:0009611
GO:0009636
GO:0009650
GO:0009725
GO:0009749
GO:0010269
GO:0010332
GO:0012501
GO:0014070
GO:0014902
GO:0016209
GO:0016491
GO:0017124
GO:0018158
GO:0019369
GO:0019372
GO:0023052
GO:0030154
GO:0030163
GO:0032355
GO:0033194
GO:0033197
GO:0033599
GO:0034599
GO:0035094
GO:0036211
GO:0040029
GO:0042060
GO:0042311
GO:0042542
GO:0042744
GO:0043154
GO:0043226
GO:0043403
GO:0043534
GO:0045444
GO:0045445
GO:0045454
GO:0047066
GO:0048144
GO:0048741
GO:0048856
GO:0048870
GO:0050877
GO:0051402
GO:0051450
GO:0051593
GO:0051702
GO:0051897
GO:0060047
GO:0060055
GO:0061136
GO:0071333
GO:0090201
GO:0097413
GO:0098754
GO:0098869
GO:1902042
GO:1902176
GO:1902905
ILMN_1749662
ILMN_1787412
PH_hs_0028977
PH_hs_0035460
TC03001407.hg
Y00433_at
g10834975_3p_a_at
Participates
as a component of
Other forms of this molecule
L-selenocysteine residue-GPX1 [cytosol]
Inferred To
Gpx1 [mitochondrial matrix] (Mus musculus)
Gpx1 [mitochondrial matrix] (Rattus norvegicus)
L-selenoC49-GPX1 [mitochondrial matrix] (Canis familiaris)
L-selenoC49-GPX1 [mitochondrial matrix] (Danio rerio)
L-selenoC49-GPX1 [mitochondrial matrix] (Gallus gallus)
L-selenoC49-GPX1 [mitochondrial matrix] (Sus scrofa)
gpx1 [mitochondrial matrix] (Xenopus tropicalis)
GPX1 [mitochondrial matrix] (Bos taurus)
gpx-5 [mitochondrial matrix] (Caenorhabditis elegans)
Modified Residues
Name
L-selenocysteine residue at 49
Coordinate
49
PsiMod Name
L-selenocysteine residue
PsiMod Definition
A protein modification that effectively converts a source amino acid residue to an L-selenocysteine, a natural pretranslational modification.
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
Orphanet
HMDB Protein
PDB
Interactors (1)
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