Peroxiredoxin 1 (PRDX1), PRDX2, and PRDX5 in the cytosol reduce hydrogen peroxide (H2O2) with thioredoxin yielding oxidized thioredoxin and water (Yamashita et al. 1999, Lee et al. 2007, Nagy et al. 2011).
Radom, L, Hampton, MB, O'Reilly, RJ, Karton, A, Nagy, P, Pace, P, Peskin, AV, Betz, A, Winterbourn, CC
Subramani, S, London, R, Avraham, S, Rogers, RA, Van Veldhoven, PP, Avraham, H, Yamashita, H, Jiang, S
Riddell, J, Park, JH, Park, YM, Ip, C, Lee, W, Ghosh, D, Choi, KS
thioredoxin peroxidase activity of PRDX1,2,5 [cytosol]
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