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Ub-121-HIST1H2BL [nucleoplasm]
Stable Identifier
R-HSA-3364013
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Histone H2B.c K121ub
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Formation of the beta-catenin:TCF transactivating complex (Homo sapiens)
SET1 complex trimethylates H3K4 at the MYC gene (Homo sapiens)
MYC gene: H2B K121ub nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H2BK121ub [nucleoplasm] (Homo sapiens)
Histone H2B K121ub [nucleoplasm] (Homo sapiens)
Ub-121-HIST1H2BL [nucleoplasm] (Homo sapiens)
MYC gene:H2B K121ub H3K4me3 nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H2BK121ub and H3K4me3 [nucleoplasm] (Homo sapiens)
Histone H2B K121ub [nucleoplasm] (Homo sapiens)
Ub-121-HIST1H2BL [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99880 H2BC13
Gene Names
H2BC13, H2BFC, HIST1H2BL
Chain
initiator methionine:, chain:2-126
Reference Genes
BioGPS Gene:8340 H2BC13
COSMIC (genes):HIST1H2BL H2BC13
CTD Gene:8340 H2BC13
dbSNP Gene:8340 H2BC13
ENSEMBL:ENSG00000185130 HIST1H2BL
HGNC:4748 H2BC13
KEGG:hsa:8340 H2BC13
Monarch:8340 H2BC13
NCBI Gene:8340 H2BC13
OMIM:602800 H2BC13
UCSC:Q99880 H2BC13
Reference Transcript
RefSeq:NM_003519.3 H2BC13
Other Identifiers
11740828_at
17016486
207611_PM_at
2947033
2947034
2947035
35576_f_at
36347_f_at
8124510
8340
ADDON002867.hg
A_23_P8013
GE511997
GO:0000786
GO:0003677
GO:0005198
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0006325
GO:0006334
GO:0030527
GO:0043226
GO:0043229
GO:0046982
GO:0065003
GO:0070062
HMNXSV003013302
ILMN_1652998
PH_hs_0029201
PH_hs_0031779
TC06001421.hg
g5579460_3p_at
Participates
as a candidate of
Histone H2B K121ub [nucleoplasm] (Homo sapiens)
Other forms of this molecule
Ub-HIST1H2BL [nucleoplasm]
AcK-HIST1H2BL [nucleoplasm]
HIST1H2BL [extracellular region]
AcK13-HIST1H2BL [nucleoplasm]
AcK16-HIST1H2BL [nucleoplasm]
AcK6-HIST1H2BL [nucleoplasm]
AcK21-HIST1H2BL [nucleoplasm]
HIST1H2BL [nucleoplasm]
Inferred To
H2Bv1 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VIII [nucleoplasm]
(Gallus gallus)
His2B [nucleoplasm]
(Drosophila melanogaster)
H2Bv2 [nucleoplasm]
(Dictyostelium discoideum)
htb1 [nucleoplasm]
(Schizosaccharomyces pombe)
Ub-121-HIST1H2BL [nucleoplasm]
(Bos taurus)
Ub-121-HIST1H2BK [nucleoplasm]
(Danio rerio)
Ub-121-HIST1H2BK [nucleoplasm]
(Plasmodium falciparum)
h2bc11 [nucleoplasm]
(Xenopus tropicalis)
HIST1H2B5L [nucleoplasm]
(Gallus gallus)
H2B-V [nucleoplasm]
(Gallus gallus)
si:ch211-113a14.22 [nucleoplasm]
(Danio rerio)
LOC100498553 [nucleoplasm]
(Xenopus tropicalis)
LOC116411635 [nucleoplasm]
(Xenopus tropicalis)
H2Bv3 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VII [nucleoplasm]
(Gallus gallus)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Danio rerio)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Dictyostelium discoideum)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Gallus gallus)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Plasmodium falciparum)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Xenopus tropicalis)
H2B-I [nucleoplasm]
(Gallus gallus)
hist2h2l [nucleoplasm]
(Danio rerio)
HTB1 [nucleoplasm]
(Saccharomyces cerevisiae)
LOC570661 [nucleoplasm]
(Danio rerio)
HTB2 [nucleoplasm]
(Saccharomyces cerevisiae)
h2bc21 [nucleoplasm]
(Xenopus tropicalis)
Modified Residues
Name
ubiquitinylated lysine at 121
Coordinate
121
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_003510.1
ENSEMBL
ENST00000377401
,
ENSG00000185130
,
ENSP00000366618
OpenTargets
ENSG00000185130
GeneCards
H2BC13
HPA
ENSG00000185130-H2BC13
PRO
Q99880
Pharos - Targets
Q99880
GlyGen
Q99880
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96CW1 AP2M1
6
AP2M1 [plasma membrane]
(R-HSA-167585)
AP2M1 [lysosomal membrane]
(R-HSA-196144)
AP2M1 [cytosol]
(R-HSA-182227)
AP2M1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130423)
AP2M1 [endolysosome membrane]
(R-HSA-6784828)
p-T156 AP2M1 [cytosol]
(R-HSA-8856805)
0.556
3
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