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Ub-121-HIST1H2BK [nucleoplasm]
Stable Identifier
R-HSA-3364019
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Histone H2B K K121ub
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Formation of the beta-catenin:TCF transactivating complex (Homo sapiens)
SET1 complex trimethylates H3K4 at the MYC gene (Homo sapiens)
MYC gene: H2B K121ub nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H2BK121ub [nucleoplasm] (Homo sapiens)
Histone H2B K121ub [nucleoplasm] (Homo sapiens)
Ub-121-HIST1H2BK [nucleoplasm] (Homo sapiens)
MYC gene:H2B K121ub H3K4me3 nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H2BK121ub and H3K4me3 [nucleoplasm] (Homo sapiens)
Histone H2B K121ub [nucleoplasm] (Homo sapiens)
Ub-121-HIST1H2BK [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60814 H2BC12
Gene Names
H2BC12, H2BFT, HIRIP1, HIST1H2BK
Chain
initiator methionine:, chain:2-126
Reference Genes
BioGPS Gene:85236 H2BC12
COSMIC (genes):HIST1H2BK H2BC12
CTD Gene:85236 H2BC12
dbSNP Gene:85236 H2BC12
ENSEMBL:ENSG00000197903 HIST1H2BK
HGNC:13954 H2BC12
KEGG:hsa:85236 H2BC12
Monarch:85236 H2BC12
NCBI Gene:85236 H2BC12
OMIM:615045 H2BC12
UCSC:O60814 H2BC12
Reference Transcript
RefSeq:NM_001312653.1 H2BC12
RefSeq:NM_080593.2 H2BC12
Other Identifiers
11717099_at
17016457
208579_PM_x_at
208579_x_at
209806_PM_at
209806_at
2946715
2946716
2946717
2946721
2946722
32819_at
35576_f_at
36347_f_at
3923212
3923213
8068898
8124492
85236
A_23_P145238
A_33_P3229083
GE553273
GE577410
GO:0000786
GO:0002227
GO:0002376
GO:0003674
GO:0003677
GO:0005198
GO:0005515
GO:0005615
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0019731
GO:0030527
GO:0031640
GO:0042742
GO:0043226
GO:0043229
GO:0046982
GO:0050829
GO:0050830
GO:0061844
GO:0098542
HMNXSV003040333
ILMN_1796179
ILMN_1813314
PH_hs_0013112
PH_hs_0037388
TC06001387.hg
TC06001388.hg
TC21000211.hg
TC21000762.hg
g12654150_3p_at
Participates
as a candidate of
Histone H2B K121ub [nucleoplasm] (Homo sapiens)
Other forms of this molecule
HIST1H2BK [nucleoplasm]
AcK21-HIST1H2BK [nucleoplasm]
AcK13-HIST1H2BK [nucleoplasm]
AcK16-HIST1H2BK [nucleoplasm]
AcK6-HIST1H2BK [nucleoplasm]
HIST1H2BK [extracellular region]
AcK-HIST1H2BK [nucleoplasm]
Ub-HIST1H2BK [nucleoplasm]
Inferred To
H2Bv1 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VIII [nucleoplasm]
(Gallus gallus)
His2B [nucleoplasm]
(Drosophila melanogaster)
H2AC12 [nucleoplasm]
(Bos taurus)
H2Bv2 [nucleoplasm]
(Dictyostelium discoideum)
htb1 [nucleoplasm]
(Schizosaccharomyces pombe)
Ub-121-HIST1H2BK [nucleoplasm]
(Danio rerio)
Ub-121-HIST1H2BK [nucleoplasm]
(Plasmodium falciparum)
h2bc11 [nucleoplasm]
(Xenopus tropicalis)
HIST1H2B5L [nucleoplasm]
(Gallus gallus)
H2B-V [nucleoplasm]
(Gallus gallus)
si:ch211-113a14.22 [nucleoplasm]
(Danio rerio)
LOC100498553 [nucleoplasm]
(Xenopus tropicalis)
LOC116411635 [nucleoplasm]
(Xenopus tropicalis)
H2Bv3 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VII [nucleoplasm]
(Gallus gallus)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Danio rerio)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Dictyostelium discoideum)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Gallus gallus)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Plasmodium falciparum)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of Ub-121-HIST1H2BK [nucleoplasm]
(Xenopus tropicalis)
H2B-I [nucleoplasm]
(Gallus gallus)
hist2h2l [nucleoplasm]
(Danio rerio)
HTB1 [nucleoplasm]
(Saccharomyces cerevisiae)
LOC570661 [nucleoplasm]
(Danio rerio)
HTB2 [nucleoplasm]
(Saccharomyces cerevisiae)
h2bc21 [nucleoplasm]
(Xenopus tropicalis)
Modified Residues
Name
ubiquitinylated lysine at 121
Coordinate
121
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_542160.1
,
NP_001299582.1
OpenTargets
ENSG00000197903
ENSEMBL
ENSP00000349430
,
ENST00000356950
,
ENSG00000197903
HPA
ENSG00000197903-H2BC12
GeneCards
H2BC12
PRO
O60814
Pharos - Targets
O60814
GlyGen
O60814
PDB
6T7B
,
7XCR
,
8HQY
,
8Q3X
,
7XD1
,
6LE9
,
7PEU
,
7PFC
,
7PEX
,
7PFD
,
7DBP
,
7PF3
,
6V92
,
7PEY
,
6T7C
,
7JZV
,
6T7D
,
7V9C
,
8Q3M
,
6T7A
,
7PFW
,
8X7I
,
7PFU
,
8JHG
,
8YV8
,
7PFE
,
8WG5
,
7PF5
,
7PEW
,
7BWD
,
2CV5
,
7PFF
,
7V96
,
8W9E
,
8JHF
,
8W9D
,
8X7J
,
6T79
,
8W9F
,
7XCT
,
7V90
,
8Q36
,
9IPU
,
8IEJ
,
7PF6
,
7PF0
,
7PF4
,
7PF2
,
7PFA
,
7PEZ
,
7V9J
,
8Q3E
,
7V9K
,
7VA4
,
7V9S
,
6L9H
,
7PFX
,
7PFT
,
7PFV
,
6KE9
,
8IEG
,
7PET
,
7PEV
,
7V99
,
8HR1
,
6Y5D
,
8X7K
,
8GRQ
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q12824 SMARCB1
1
SMARCB1 [nucleoplasm]
(R-HSA-389261)
0.576
5
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