Reactome | DNAJA2 [cytosol]

DNAJA2 [cytosol]

Stable Identifier

R-HSA-3371555

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

DnaJ homolog subfamily A member 2, Dnj3, Dj3, HIRA-interacting protein 4, Renal carcinoma antigen NY-REN-14, CPR3, HIRIP4

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O60884 DNAJA2

Gene Names

DNAJA2, CPR3, HIRIP4

Chain

chain:1-409, propeptide:410-412

Reference Genes

BioGPS Gene:10294 DNAJA2

COSMIC (genes):DNAJA2 DNAJA2

CTD Gene:10294 DNAJA2

dbSNP Gene:10294 DNAJA2

ENSEMBL:ENSG00000069345.12 DNAJA2

HGNC:14884 DNAJA2

KEGG Gene (Homo sapiens):10294 DNAJA2

Monarch:10294 DNAJA2

NCBI Gene:10294 DNAJA2

OMIM:611322 DNAJA2

UCSC:O60884 DNAJA2

Reference Transcript

RefSeq:NM_005880.3 DNAJA2

Other Identifiers

0006180110

10294

11723647_a_at

11723648_at

16826218

209157_PM_at

209157_at

226994_PM_at

226994_at

34201_at

3690085

3690086

3690087

3690088

3690089

3690090

3690091

3690092

3690095

3690096

3690099

3690100

3690101

3690103

3690105

3690108

3690109

51644_at

79710_r_at

8001185

A_23_P15090

A_33_P3414574

GE58384

GO:0001671

GO:0005515

GO:0005524

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005829

GO:0006457

GO:0008284

GO:0009408

GO:0016020

GO:0030544

GO:0031072

GO:0042026

GO:0043226

GO:0046872

GO:0051082

GO:0051087

GO:0070062

GO:0098772

HMNXSV003045683

Hs.21189.2.A1_3p_at

ILMN_1770127

PH_hs_0024056

TC16001087.hg

g2352903_3p_a_at

g2352903_3p_at

g2352903_3p_x_at

Participates

as a component of

DNAJA2 dimer [cytosol] (Homo sapiens)

Inferred To

APJ1 [cytosol] (Saccharomyces cerevisiae)

ddj1 [cytosol] (Dictyostelium discoideum)

DNAJA2 [cytosol] (Bos taurus)

DNAJA2 [cytosol] (Canis familiaris)

DNAJA2 [cytosol] (Dictyostelium discoideum)

DNAJA2 [cytosol] (Gallus gallus)

DNAJA2 [cytosol] (Mus musculus)

DNAJA2 [cytosol] (Plasmodium falciparum)

DNAJA2 [cytosol] (Rattus norvegicus)

DNAJA2 [cytosol] (Saccharomyces cerevisiae)

DNAJA2 [cytosol] (Schizosaccharomyces pombe)

DNAJA2 [cytosol] (Sus scrofa)

dnj-19 [cytosol] (Caenorhabditis elegans)

Homologues of DNAJA2 [cytosol] (Dictyostelium discoideum)

Homologues of DNAJA2 [cytosol] (Saccharomyces cerevisiae)

dnaja2 [cytosol] (Danio rerio)

dnaja2 [cytosol] (Xenopus tropicalis)

DnaJ-H [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_005871.1

OpenTargets

ENSG00000069345

GeneCards

O60884

HPA

ENSG00000069345-DNAJA2

Ensembl

ENSP00000314030, ENSG00000069345, ENST00000317089

PRO

O60884

Pharos - Targets

O60884

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04626 ERBB2	20	ERBB2 G309E [plasma membrane] (R-HSA-9665342) ERBB2 G309A [plasma membrane] (R-HSA-9665349) ERBB2 S310F [plasma membrane] (R-HSA-9665350) ERBB2 S310Y [plasma membrane] (R-HSA-9665344) p-6Y-ERBB2 G309A [plasma membrane] (R-HSA-9665381) p-6Y-ERBB2 G309E [plasma membrane] (R-HSA-9665382) p-6Y-ERBB2 S310F [plasma membrane] (R-HSA-9665379) p-6Y-ERBB2 S310Y [plasma membrane] (R-HSA-9665385) p-Y-ERBB2 L755P [plasma membrane] (R-HSA-9654268) p-Y-ERBB2 I767M [plasma membrane] (R-HSA-9654303) p-Y-ERBB2 A775_G776insYVMA [plasma membrane] (R-HSA-9665656) p-Y-ERBB2 T798I [plasma membrane] (R-HSA-9654618) p-Y-ERBB2 T862A [plasma membrane] (R-HSA-9654695) p-Y-ERBB2 T798M [plasma membrane] (R-HSA-9654615) p-Y-ERBB2 H878Y [plasma membrane] (R-HSA-9654833) p-Y-ERBB2 V777L [plasma membrane] (R-HSA-9654401) p-Y-ERBB2 L755S [plasma membrane] (R-HSA-9654194) p-Y-ERBB2 V777E [plasma membrane] (R-HSA-9654397) p-Y-ERBB2 V777M [plasma membrane] (R-HSA-9654398) p-Y-ERBB2 L755M [plasma membrane] (R-HSA-9654191)	0.569	3
UniProt:Q8IWL3 HSCB	5	HSCB [mitochondrial matrix] (R-HSA-1299438) HSCB [mitochondrial inner membrane] (R-HSA-1299447) HSCB(1-235) [mitochondrial inner membrane] (R-HSA-1299443) HSCB(1-30) [mitochondrial matrix] (R-HSA-8986120) HSCB(1-235) [mitochondrial intermembrane space] (R-HSA-1299456)	0.547	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.527	4
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR M766_A767insASV [plasma membrane] (R-HSA-1996343) p-6Y-EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996342) p-6Y-EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.527	2
UniProt:P51617 IRAK1	14	K63polyUb-hp-IRAK1 [endosome membrane] (R-HSA-975112) p-S376,T387-IRAK1 [cytosol] (R-HSA-446687) p-S,T-IRAK1 [cytosol] (R-HSA-3149574) K63polyUb-hp-IRAK1 [cytosol] (R-HSA-451565) p-T209-IRAK1 [endosome membrane] (R-HSA-975189) p-T209,T387-IRAK1 [endosome membrane] (R-HSA-975117) IRAK1 [endosome membrane] (R-HSA-975127) p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (R-HSA-975157) IRAK1 [plasma membrane] (R-HSA-937045) p-T209-IRAK1 [plasma membrane] (R-HSA-937031) p-T209,T387-IRAK1 [plasma membrane] (R-HSA-166279) p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (R-HSA-937011) p-2S,S376,T,T209,T387-IRAK1 [cytosol] (R-HSA-446682) IRAK1 [cytosol] (R-HSA-446639)	0.527	2
UniProt:Q9Y266 NUDC	4	p-S274,S326-NUDC [spindle] (R-HSA-9648125) p-S274,S326-NUDC [cytosol] (R-HSA-156702) NUDC [nucleoplasm] (R-HSA-156716) NUDC [cytosol] (R-HSA-377731)	0.499	2

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