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OAZ1 [cytosol]
Stable Identifier
R-HSA-350587
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ornithine decarboxylase antizyme 1
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of polyamines (Homo sapiens)
Regulation of ornithine decarboxylase (ODC) (Homo sapiens)
26S proteosome degrades ODC holoenzyme complex (Homo sapiens)
OAZ [cytosol] (Homo sapiens)
OAZ1 [cytosol] (Homo sapiens)
ODC:OAZ complex [cytosol] (Homo sapiens)
OAZ [cytosol] (Homo sapiens)
OAZ1 [cytosol] (Homo sapiens)
Antizyme OAZ binds to Ornithine decarboxylase (Homo sapiens)
OAZ [cytosol] (Homo sapiens)
OAZ1 [cytosol] (Homo sapiens)
ODC:OAZ complex [cytosol] (Homo sapiens)
OAZ [cytosol] (Homo sapiens)
OAZ1 [cytosol] (Homo sapiens)
Antizyme inhibitor binds to OAZ and stablizes ODC complex (Homo sapiens)
AZIN1 bound OAZ:ODC complex [cytosol] (Homo sapiens)
AZIN1 bound OAZ [cytosol] (Homo sapiens)
OAZ [cytosol] (Homo sapiens)
OAZ1 [cytosol] (Homo sapiens)
ODC:OAZ complex [cytosol] (Homo sapiens)
OAZ [cytosol] (Homo sapiens)
OAZ1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P54368 OAZ1
Gene Names
OAZ1, OAZ
Chain
chain:1-228
Reference Genes
BioGPS Gene:4946 OAZ1
COSMIC (genes):OAZ1 OAZ1
CTD Gene:4946 OAZ1
dbSNP Gene:4946 OAZ1
ENSEMBL:ENSG00000104904 OAZ1
ENSEMBL_homo_sapiens_GENE:ENSG00000104904.12 OAZ1
HGNC:8095 OAZ1
KEGG Gene (Homo sapiens):4946 OAZ1
Monarch:4946 OAZ1
NCBI Gene:4946 OAZ1
OMIM:601579 OAZ1
UCSC:P54368 OAZ1
Reference Transcript
RefSeq:NM_004152.3 OAZ1
Other Identifiers
11751655_a_at
11753368_a_at
11753821_x_at
11755995_x_at
11756169_x_at
1315_at
16856757
18671123
18671124
18671125
18671126
18671127
18671128
200077_PM_s_at
200077_s_at
215952_3p_s_at
215952_PM_s_at
215952_s_at
3816384
3816385
3816390
3816391
3816394
3816396
3816398
3816399
3816400
3816401
3816402
3816403
3816404
3816405
4946
7892564
7893808
7894185
7894262
7894471
7894596
7894704
7895447
8024436
A_14_P105760
A_23_P409945
A_23_P409951
D78361_at
GE57300
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0006596
GO:0006886
GO:0008073
GO:0030163
GO:0043226
GO:0045732
GO:0055085
GO:0090316
GO:0098772
GO:1902268
HMNXSV003044514
Hs.125078.2.S1_3p_s_at
ILMN_1773080
PH_hs_0026094
TC19002618.hg
g1590807_3p_s_at
Participates
as a member of
OAZ [cytosol] (Homo sapiens)
Inferred To
spa1 [cytosol]
(Schizosaccharomyces pombe)
Oda [cytosol]
(Drosophila melanogaster)
Oaz1 [cytosol]
(Mus musculus)
Oaz1 [cytosol]
(Rattus norvegicus)
oaz1a [cytosol]
(Danio rerio)
OAZ [cytosol]
(Gallus gallus)
OAZ1 [cytosol]
(Bos taurus)
OAZ1 [cytosol]
(Canis familiaris)
OAZ1 [cytosol]
(Sus scrofa)
oaz-1 [cytosol]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_004143.1
OpenTargets
ENSG00000104904
GeneCards
P54368
HPA
ENSG00000104904-OAZ1
Ensembl
ENST00000602676
,
ENSP00000473381
,
ENSG00000104904
PRO
P54368
Pharos - Targets
P54368
PDB
4ZGZ
,
4ZGY
,
5BWA
HMDB Protein
HMDBP10709
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14977 AZIN1
1
AZIN1 [cytosol]
(R-HSA-350615)
0.643
3
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.553
2
UniProt:Q96A70 AZIN2
1
ADC [cytosol]
(R-HSA-2975982)
0.527
2
UniProt:P30556 AGTR1
2
AGTR1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869071)
AGTR1 [plasma membrane]
(R-HSA-374247)
0.508
2
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