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NQO1 [cytosol]
Stable Identifier
R-HSA-350610
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
KEAP1-NFE2L2 pathway (Homo sapiens)
Nuclear events mediated by NFE2L2 (Homo sapiens)
NFE2L2 regulating anti-oxidant/detoxification enzymes (Homo sapiens)
AcK-NFE2L2- dependent NQO1 gene expression (Homo sapiens)
NQO1:FAD dimer [cytosol] (Homo sapiens)
NQO1 [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of polyamines (Homo sapiens)
Regulation of ornithine decarboxylase (ODC) (Homo sapiens)
NQO1 interaction with ODC (Homo sapiens)
NQO1 [cytosol] (Homo sapiens)
ODC:NQO1 complex [cytosol] (Homo sapiens)
NQO1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P15559 NQO1
Gene Names
NQO1, DIA4, NMOR1
Chain
chain:1-274
Reference Genes
BioGPS Gene:1728 NQO1
COSMIC (genes):NQO1 NQO1
CTD Gene:1728 NQO1
dbSNP Gene:1728 NQO1
ENSEMBL:ENSG00000181019 NQO1
ENSEMBL_homo_sapiens_GENE:ENSG00000181019.13 NQO1
HGNC:2874 NQO1
KEGG Gene (Homo sapiens):1728 NQO1
Monarch:1728 NQO1
NCBI Gene:1728 NQO1
UCSC:P15559 NQO1
Reference Transcript
RefSeq:NM_001025434.1 NQO1
RefSeq:NM_001025433.1 NQO1
RefSeq:NM_000903.2 NQO1
Other Identifiers
11717567_a_at
11717568_s_at
16827677
16827679
1728
201467_PM_s_at
201467_s_at
201468_PM_s_at
201468_s_at
210519_PM_s_at
210519_s_at
3696674
3696675
3696676
3696677
3696678
3696679
3696681
3696683
3696686
3696687
3696689
38066_at
8002301
8002303
A_23_P206661
GE61408
GO:0000209
GO:0002376
GO:0002931
GO:0003723
GO:0003824
GO:0003955
GO:0004128
GO:0004784
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0006116
GO:0006743
GO:0006766
GO:0006801
GO:0006805
GO:0006809
GO:0006979
GO:0007271
GO:0007584
GO:0008753
GO:0009410
GO:0009636
GO:0009725
GO:0009743
GO:0010033
GO:0012501
GO:0014070
GO:0014075
GO:0016209
GO:0016491
GO:0019430
GO:0023052
GO:0030163
GO:0030425
GO:0032355
GO:0032496
GO:0033574
GO:0034599
GO:0036211
GO:0042177
GO:0042360
GO:0042373
GO:0042802
GO:0043025
GO:0043066
GO:0043226
GO:0043279
GO:0043525
GO:0045087
GO:0045202
GO:0045454
GO:0045471
GO:0050136
GO:0051602
GO:0055086
GO:0070301
GO:0070995
GO:0071248
GO:0098542
GO:0098754
GO:1901698
GO:1904772
GO:1904844
GO:1904880
GO:1905395
HMNXSV003017321
Hs.80706.0.A1_3p_a_at
ILMN_1720282
ILMN_2354953
J03934_s_at
PH_hs_0019286
TC16001224.hg
TC16001225.hg
g4505414_3p_a_at
Participates
as a component of
NQO1:FAD dimer [cytosol] (Homo sapiens)
ODC:NQO1 complex [cytosol] (Homo sapiens)
as an input of
NQO1 interaction with ODC (Homo sapiens)
Inferred To
NQO1 [cytosol]
(Bos taurus)
NQO1 [cytosol]
(Canis familiaris)
NQO1 [cytosol]
(Mus musculus)
NQO1 [cytosol]
(Rattus norvegicus)
NQO1 [cytosol]
(Sus scrofa)
nqo1 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001020605.1
,
NP_001020604.1
,
NP_000894.1
ZINC - World Drugs
NQO1_HUMAN
OpenTargets
ENSG00000181019
ZINC - Substances
NQO1_HUMAN
ZINC target
P15559
ZINC - Biogenic
NQO1_HUMAN
PRO
P15559
PDB
4CF6
,
8C9J
,
1KBO
,
1KBQ
,
1H66
,
4CET
,
1GG5
,
2F1O
,
1QBG
,
5EA2
,
3JSX
,
1DXO
,
6LLC
,
5EAI
,
1D4A
,
6FY4
,
5FUQ
,
5A4K
,
1H69
GeneCards
P15559
HPA
ENSG00000181019-NQO1
Ensembl
ENSP00000368335
,
ENSP00000368334
,
ENST00000379047
,
ENST00000320623
,
ENST00000379046
,
ENSP00000319788
,
ENSG00000181019
Pharos - Targets
P15559
ZINC - Predictions - Purchasable
NQO1_HUMAN
HMDB Protein
HMDBP01689
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P15559 NQO1
1
NQO1 [cytosol]
(R-HSA-350610)
0.618
5
UniProt:P07902 GALT
4
GALT Q188R [cytosol]
(R-HSA-5610008)
GALT K285N [cytosol]
(R-HSA-5610009)
GALT S135L [cytosol]
(R-HSA-5610004)
GALT [cytosol]
(R-HSA-70356)
0.556
3
UniProt:Q9UK53 ING1
0.544
3
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