Reactome | CALU [endoplasmic reticulum lumen]

CALU [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-350695

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Calumenin

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43852 CALU

Gene Names

CALU

Chain

signal peptide:1-19, chain:20-315

Reference Genes

BioGPS Gene:813 CALU

COSMIC (genes):CALU CALU

CTD Gene:813 CALU

dbSNP Gene:813 CALU

ENSEMBL:ENSG00000128595 CALU

ENSEMBL_homo_sapiens_GENE:ENSG00000128595.17 CALU

HGNC:1458 CALU

KEGG Gene (Homo sapiens):813 CALU

Monarch:813 CALU

NCBI Gene:813 CALU

OMIM:603420 CALU

UCSC:O43852 CALU

Reference Transcript

Other Identifiers

11725306_s_at

11725307_s_at

11725308_a_at

17051236

200755_PM_s_at

200755_s_at

200756_PM_x_at

200756_x_at

200757_PM_s_at

200757_s_at

214845_PM_s_at

214845_s_at

229549_PM_at

229549_at

3023061

3023067

3023068

3023070

3023073

3023075

3023078

3023079

3023082

3023084

3023085

3023086

3023087

3023088

3023089

3023090

3023091

3023092

3023094

37345_at

52813_at

813

8135955

83794_at

A_14_P127960

A_23_P122815

GE58250

GE83826

GE86010

GO:0005509

GO:0005515

GO:0005576

GO:0005783

GO:0005788

GO:0005789

GO:0005794

GO:0008150

GO:0016020

GO:0016529

GO:0031410

GO:0033018

GO:0042470

GO:0043226

GO:0046872

HMNXSV003021267

HMNXSV003043944

Hs.302073.0.S1_3p_s_at

Hs.7753.0.S2_3p_a_at

Hs.7753.0.S2_3p_s_at

Hs.7753.2.S1_3p_at

ILMN_1727194

PH_hs_0000799

PH_hs_0039542

TC07000782.hg

TC07002576.hg

g6005991_3p_a_at

Participates

as an input of

Release of Calumenin (Homo sapiens)

as a member of

FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

p-CALU [endoplasmic reticulum lumen]

CALU [extracellular region]

Inferred To

scf [endoplasmic reticulum lumen] (Drosophila melanogaster)

CALU [endoplasmic reticulum lumen] (Bos taurus)

CALU [endoplasmic reticulum lumen] (Canis familiaris)

CALU [endoplasmic reticulum lumen] (Gallus gallus)

CALU [endoplasmic reticulum lumen] (Sus scrofa)

CALU [endoplasmic reticulum lumen] (Xenopus tropicalis)

Calumenin [endoplasmic reticulum lumen] (Mus musculus)

calu-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001186600.1, NP_001210.1, XP_016868148.1, NP_001186602.1, NP_001124146.1, NP_001186601.1

OpenTargets

ENSG00000128595

HPA

ENSG00000128595-CALU

GeneCards

O43852

Ensembl

ENSP00000249364, ENSP00000408838, ENST00000542996, ENSP00000442110, ENSP00000438248, ENST00000449187, ENSG00000128595, ENST00000249364, ENST00000535011, ENST00000479257, ENSP00000420381

PRO

O43852

Pharos - Targets

O43852

HMDB Protein

HMDBP07534

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.706	13
UniProt:P04049 RAF1	20	p-S338,Y340,Y341-RAF1 [cytosol] (R-HSA-5624465) p-S338-RAF1 [cytosol] (R-HSA-5624469) p-S621-RAF1 S259F [cytosol] (R-HSA-9656124) p-S621-RAF1 S257L [cytosol] (R-HSA-9656121) p-S621-RAF1 P261L [cytosol] (R-HSA-9656106) p-S621-RAF1 N262K [cytosol] (R-HSA-9656101) p-S621-RAF1 P261A [cytosol] (R-HSA-9656103) p-S621-RAF1 P261S [cytosol] (R-HSA-9656113) p-S621-RAF1 S259T [cytosol] (R-HSA-9656130) p-S621-RAF1 P261T [cytosol] (R-HSA-9656115) p-S621-RAF1 P261R [cytosol] (R-HSA-9656110) p-S621-RAF1 S259P [cytosol] (R-HSA-9656127) p-S621-RAF1 T260I [cytosol] (R-HSA-9656136) p-S621-RAF1 T260R [cytosol] (R-HSA-9656139) p-S621-RAF1 V263A [cytosol] (R-HSA-9656148) p-S621-RAF1 R256S [cytosol] (R-HSA-9656119) p-S621-RAF1 T491I [cytosol] (R-HSA-9656143) p-S621-RAF1 D486N [cytosol] (R-HSA-9656088) p-S621-RAF1 S427G [cytosol] (R-HSA-9656134) p-S621-RAF1 L613V [cytosol] (R-HSA-9656098)	0.643	4
UniProt:Q9UMX0-2 UBQLN1			0.556	3
UniProt:Q05513 PRKCZ	5	p-T410,T563-PRKCZ [cytosol] (R-HSA-5218698) PRKCZ [cytosol] (R-HSA-58218) PRKCZ [cell junction] (R-HSA-2134483) p-T410-PRKCZ [cytosol] (R-HSA-437181) pS, p-T410-PRKCZ [cytosol] (R-HSA-9632824)	0.527	2
UniProt:P0DTD1-PRO_0000449619 REP			0.508	2

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