Reactome | SAT1 [cytosol]

SAT1 [cytosol]

Stable Identifier

R-HSA-351236

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

SSAT-1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P21673 SAT1

Gene Names

SAT1, SAT

Chain

chain:1-171

Reference Genes

BioGPS Gene:6303 SAT1

COSMIC (genes):SAT1 SAT1

CTD Gene:6303 SAT1

dbSNP Gene:6303 SAT1

ENSEMBL:ENSG00000130066.17 SAT1

HGNC:10540 SAT1

KEGG Gene (Homo sapiens):6303 SAT1

Monarch:6303 SAT1

NCBI Gene:6303 SAT1

OMIM:313020 SAT1

UCSC:P21673 SAT1

Reference Transcript

RefSeq:NM_002970.3 SAT1

Other Identifiers

0006400717

1173_g_at

11743036_s_at

11763704_a_at

17102129

203455_PM_s_at

203455_s_at

210592_PM_s_at

210592_s_at

213988_PM_s_at

213988_s_at

34304_s_at

3971809

3971810

3971811

3971813

3971815

3971822

3971824

3971826

3971827

3971828

6303

8166469

A_23_P137016

A_23_P378722

A_33_P3371718

GE61351

GO:0001525

GO:0004145

GO:0005515

GO:0005622

GO:0005737

GO:0005829

GO:0006596

GO:0008080

GO:0009447

GO:0016407

GO:0016740

GO:0016746

GO:0019809

GO:0032918

GO:0042802

GO:0048856

HMNXSV003036752

Hs.28491.3.A1_3p_a_at

ILMN_1753342

PH_hs_0002492

PH_hs_0035404

TC0X001624.hg

U40369_rna1_at

g4506788_3p_a_at

p33849

Inferred To

ats1 [cytosol] (Schizosaccharomyces pombe)

BcDNA:SD26038 [cytosol] (Drosophila melanogaster)

Sat1 [cytosol] (Rattus norvegicus)

sat1 [cytosol] (Danio rerio)

sat1 [cytosol] (Xenopus tropicalis)

SAT1 [cytosol] (Bos taurus)

SAT1 [cytosol] (Caenorhabditis elegans)

SAT1 [cytosol] (Dictyostelium discoideum)

SAT1 [cytosol] (Gallus gallus)

SAT1 [cytosol] (Mus musculus)

SAT1 [cytosol] (Saccharomyces cerevisiae)

SAT1 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_002961.1

ZINC - World Drugs

SAT1_HUMAN

OpenTargets

ENSG00000130066

ZINC - FDA approved

SAT1_HUMAN

ZINC - Substances

SAT1_HUMAN

ZINC - Biogenic

SAT1_HUMAN

ZINC target

P21673

PRO

P21673

PDB

2B3V, 2G3T, 2B3U, 2B4D, 2JEV, 2B5G, 2B4B, 2FXF, 2F5I, 2B58

GeneCards

P21673

HPA

ENSG00000130066-SAT1

Ensembl

ENSP00000368572, ENST00000379270, ENSG00000130066

Pharos - Targets

P21673

Orphanet

23050

ZINC - Predictions - Purchasable

SAT1_HUMAN

HMDB Protein

HMDBP00029

Interactors (47)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BQ70 TCF25			0.911	11
UniProt:Q96I25 RBM17	1	RBM17 [nucleoplasm] (R-HSA-8865891)	0.87	13
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.83	8
UniProt:P17482 HXB9			0.764	6
UniProt:P21673 SAT1	1	SAT1 [cytosol] (R-HSA-351236)	0.743	4
UniProt:Q96F10 SAT2			0.742	5
UniProt:Q8TD31-3 CCHCR1			0.718	6
UniProt:Q5VUD6 DIK1B			0.718	6
UniProt:Q9NQL9 DMRT3			0.718	6
UniProt:P55210 CASP7	5	CASP7(24-198) [nucleoplasm] (R-HSA-351927) CASP7(207-303) [nucleoplasm] (R-HSA-351924) CASP7(2-303) [cytosol] (R-HSA-57029) CASP7(24-198) [cytosol] (R-HSA-141641) CASP7(207-303) [cytosol] (R-HSA-141642)	0.718	6
UniProt:Q8NFR7 CC148			0.696	5
UniProt:Q9GZT8 NIF3L			0.696	5
UniProt:Q9BSH4 TACO1	1	TACO1 [mitochondrial matrix] (R-HSA-5336153)	0.666	4
UniProt:P22459 KCNA4	1	KCNA4 [plasma membrane] (R-HSA-977474)	0.666	4
UniProt:Q15561 TEAD4	1	TEAD4 [nucleoplasm] (R-HSA-2032780)	0.556	3
UniProt:Q99757 TXN2	2	TXN2 [mitochondrial matrix] (R-HSA-3323048) 2xHC-TXN2 [mitochondrial matrix] (R-HSA-3323059)	0.556	3
UniProt:Q04864 REL	2	REL [cytosol] (R-HSA-1168579) REL [nucleoplasm] (R-HSA-1168585)	0.556	3
UniProt:P19237 TNNI1	1	TNNI1 [cytosol] (R-HSA-390539)	0.556	3
UniProt:Q86VE0 MYPOP			0.556	3
UniProt:O15371 EIF3D	1	EIF3D [cytosol] (R-HSA-72548)	0.556	3
UniProt:P52815 MRPL12	1	MRPL12 [mitochondrial inner membrane] (R-HSA-5368256)	0.556	3
UniProt:Q86W67 F228A			0.556	3
UniProt:Q9BUL9 RPP25	1	RPP25 [nucleoplasm] (R-HSA-5696782)	0.556	8
UniProt:P09669 COX6C	1	COX6C(3-75) [mitochondrial inner membrane] (R-HSA-164298)	0.556	3
UniProt:Q13330 MTA1	2	MTA1 [nucleoplasm] (R-HSA-3465550) polySUMO2,3-K509-MTA1 [nucleoplasm] (R-HSA-3465537)	0.556	3
UniProt:Q9UBR4-2 LHX3			0.556	5
UniProt:Q8N6Y0 USBP1			0.556	3
UniProt:Q6UXT9 ABH15			0.556	3
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:O00148 DDX39A	1	DDX39A [nucleoplasm] (R-HSA-8852237)	0.556	3
UniProt:Q7Z7F0-4 KHDC4			0.556	3
UniProt:Q6FHY5 Q6FHY5			0.556	3
UniProt:Q00587-2 CDC42EP1			0.556	3
UniProt:Q9UFG5 CS025			0.556	3
UniProt:P25786 PSMA1	2	PSMA1 [nucleoplasm] (R-HSA-174333) PSMA1 [cytosol] (R-HSA-68724)	0.556	3
UniProt:Q9NVL1-2 FAM86C1P			0.556	3
UniProt:Q08117-2 TLE5			0.556	3
UniProt:Q6ZNM6 TEX43			0.556	3
UniProt:O43623 SNAI2	1	SNAI2 [nucleoplasm] (R-HSA-2980898)	0.556	3
UniProt:Q8NHY3 GA2L2			0.556	3
UniProt:Q7RTU4 BHA09			0.556	3
UniProt:Q96HA8 NTAQ1			0.556	3
UniProt:Q8NDB6 FA156			0.556	3
UniProt:Q5U5X0 LYRM7			0.556	3
UniProt:P07954 FH	1	FH [mitochondrial matrix] (R-HSA-70980)	0.556	3
UniProt:Q9BYD2 MRPL9	1	MRPL9 [mitochondrial inner membrane] (R-HSA-5368262)	0.488	2
UniProt:P50552 VASP	1	VASP [cytosol] (R-HSA-446323)	0.488	2

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