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SIN3A,(SIN3B) [nucleoplasm]
Stable Identifier
R-HSA-351660
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SIN3
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Negative epigenetic regulation of rRNA expression (Homo sapiens)
NoRC negatively regulates rRNA expression (Homo sapiens)
NoRC:HDAC:DNMT deacetylates histone H4 and methylates histone H3 (Homo sapiens)
NoRC:pRNA:HDAC:DNMT [nucleoplasm] (Homo sapiens)
SIN3 HDAC corepressor complex [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
NoRC:HDAC:DNMT methylates cytosine of the rRNA genes (Homo sapiens)
NoRC:pRNA:HDAC:DNMT [nucleoplasm] (Homo sapiens)
SIN3 HDAC corepressor complex [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
Nucleolar Remodelling Complex (NoRC) binds intergenic region of rDNA (Homo sapiens)
NoRC:pRNA:HDAC:DNMT [nucleoplasm] (Homo sapiens)
SIN3 HDAC corepressor complex [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
SIN3 HDAC corepressor complex [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Homo sapiens)
GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1 binds SIN3A,(SIN3B) co-repressor (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the GP1BA promoter (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the ITGA2B promoter (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the MIR27A gene promoter (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the THBS1 gene promoter (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
SIN3A,(SIN3B) [nucleoplasm] (Homo sapiens)
Participants
members
SIN3A [nucleoplasm]
(Homo sapiens)
candidates
SIN3B [nucleoplasm]
(Homo sapiens)
Participates
as a component of
SIN3 HDAC corepressor complex [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Homo sapiens)
as an input of
RUNX1 binds SIN3A,(SIN3B) co-repressor (Homo sapiens)
Inferred To
Sin3A [nucleoplasm]
(Drosophila melanogaster)
SIN3 [nucleoplasm]
(Saccharomyces cerevisiae)
SIN3A,(SIN3B) [nucleoplasm]
(Bos taurus)
SIN3A,(SIN3B) [nucleoplasm]
(Canis familiaris)
SIN3A,(SIN3B) [nucleoplasm]
(Danio rerio)
SIN3A,(SIN3B) [nucleoplasm]
(Dictyostelium discoideum)
SIN3A,(SIN3B) [nucleoplasm]
(Gallus gallus)
SIN3A,(SIN3B) [nucleoplasm]
(Mus musculus)
SIN3A,(SIN3B) [nucleoplasm]
(Rattus norvegicus)
SIN3A,(SIN3B) [nucleoplasm]
(Schizosaccharomyces pombe)
SIN3A,(SIN3B) [nucleoplasm]
(Sus scrofa)
SIN3A,(SIN3B) [nucleoplasm]
(Xenopus tropicalis)
sin-3 [nucleoplasm]
(Caenorhabditis elegans)
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