Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
MST4(1-305) [cytosol]
Stable Identifier
R-HSA-351855
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
MASK fragment (1-305)
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Apoptotic execution phase (Homo sapiens)
Apoptotic cleavage of cellular proteins (Homo sapiens)
Caspase-mediated cleavage of MASK (Homo sapiens)
MST4(1-305) [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9P289 STK26
Gene Names
STK26, MASK, MST4
Chain
initiator methionine:, chain:2-416
Reference Genes
BioGPS Gene:51765 STK26
COSMIC (genes):STK26 STK26
CTD Gene:51765 STK26
dbSNP Gene:51765 STK26
ENSEMBL:ENSG00000134602 STK26
ENSEMBL_homo_sapiens_GENE:ENSG00000134602.16 STK26
HGNC:18174 STK26
KEGG Gene (Homo sapiens):51765 STK26
Monarch:51765 STK26
NCBI Gene:51765 STK26
OMIM:300547 STK26
UCSC:Q9P289 STK26
Reference Transcript
RefSeq:NM_001042452.1 STK26
RefSeq:NM_016542.3 STK26
RefSeq:NM_001042453.1 STK26
Other Identifiers
11720115_a_at
11720116_a_at
11741309_x_at
11747272_a_at
17106997
218499_PM_at
218499_at
224407_PM_s_at
224407_s_at
3991113
3991114
3991115
3991116
3991117
3991126
3991129
3991131
3991132
3991133
3991135
3991136
3991138
3991139
3991141
3991142
3991143
3991145
3991146
43456_at
51765
54316_at
8169949
A_14_P113118
A_23_P32414
GE53978
GO:0000166
GO:0000287
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005737
GO:0005794
GO:0005798
GO:0005829
GO:0005886
GO:0006468
GO:0006915
GO:0009267
GO:0012501
GO:0012506
GO:0016020
GO:0016301
GO:0016310
GO:0016324
GO:0016740
GO:0023052
GO:0030033
GO:0030336
GO:0031098
GO:0031410
GO:0034599
GO:0035556
GO:0036211
GO:0042802
GO:0042803
GO:0042981
GO:0043226
GO:0046777
GO:0046872
GO:0048471
GO:0048870
GO:0070062
GO:0071944
GO:0106310
GO:0140096
HMNXSV003027586
ILMN_1676159
ILMN_2328776
PH_hs_0002081
TC0X000628.hg
g13549066_3p_s_at
g7706568_3p_at
Participates
as an output of
Caspase-mediated cleavage of MASK (Homo sapiens)
Other forms of this molecule
MST4(306-416) [cytosol]
MST4 [cytosol]
Inferred To
Homologues of MST4(1-305) [cytosol]
(Dictyostelium discoideum)
Homologues of MST4(1-305) [cytosol]
(Schizosaccharomyces pombe)
MST4(1-305) [cytosol]
(Danio rerio)
MST4(1-305) [cytosol]
(Dictyostelium discoideum)
MST4(1-305) [cytosol]
(Gallus gallus)
MST4(1-305) [cytosol]
(Mus musculus)
MST4(1-305) [cytosol]
(Rattus norvegicus)
MST4(1-305) [cytosol]
(Saccharomyces cerevisiae)
MST4(1-305) [cytosol]
(Schizosaccharomyces pombe)
MST4(1-305) [cytosol]
(Sus scrofa)
MST4(1-305) [cytosol]
(Xenopus tropicalis)
STK26 [cytosol]
(Bos taurus)
STK26 [cytosol]
(Canis familiaris)
Cross References
RefSeq
NP_057626.2
,
NP_001035918.1
,
NP_001035917.1
ZINC - World Drugs
STK26_HUMAN
Guide to Pharmacology - Targets
2287
OpenTargets
ENSG00000134602
ZINC - FDA approved
STK26_HUMAN
ZINC - Substances
STK26_HUMAN
ZINC - Biogenic
STK26_HUMAN
ZINC target
Q9P289
PRO
Q9P289
PDB
4FZA
,
7B36
,
4FZF
,
4GEH
,
3W8I
,
5XY9
,
5YF4
,
4FZD
,
3GGF
ZINC - Investigational
STK26_HUMAN
HPA
ENSG00000134602-STK26
GeneCards
Q9P289
Ensembl
ENSP00000419702
,
ENST00000394334
,
ENSP00000377868
,
ENSG00000134602
,
ENSP00000377867
,
ENST00000394335
,
ENST00000496850
Pharos - Targets
Q9P289
ZINC - Predictions - Purchasable
STK26_HUMAN
HMDB Protein
HMDBP08763
Interactors (24)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BUL8 PDC10
0.924
11
UniProt:Q13033 STRN3
0.877
10
UniProt:O43815 STRN
5
STRN [cytosol]
(R-HSA-9037081)
STRN(1-265)-PDGFRA(580-1089) fusion [cytosol]
(R-HSA-9673902)
p-11Y-STRN(1-265)-PDGFRA(580-1089) fusion [cytosol]
(R-HSA-9673908)
STRN(1-137)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9700485)
STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9700467)
0.864
7
UniProt:Q9Y3A3 PHOCN
0.812
6
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.81
7
UniProt:Q9P2B4 CT2NL
0.794
6
UniProt:P30153 PPP2R1A
2
PPP2R1A [nucleoplasm]
(R-HSA-165968)
PPP2R1A [cytosol]
(R-HSA-165982)
0.788
5
UniProt:Q14BN4 SLMAP
0.788
5
UniProt:O00506 STK25
0.788
6
UniProt:Q8WZ74 CTTB2
0.758
5
UniProt:Q9NRL3 STRN4
0.725
4
UniProt:Q9ULQ0 STRP2
0.725
4
UniProt:Q9Y6E0 STK24
4
STK24(1-313) [nucleoplasm]
(R-HSA-351944)
STK24(314-443) [cytosol]
(R-HSA-351898)
STK24(1-313) [cytosol]
(R-HSA-351892)
STK24 [cytosol]
(R-HSA-351829)
0.725
6
UniProt:Q5VSL9 STRP1
0.708
4
UniProt:Q9BRV8 SIKE1
1
SIKE1 [cytosol]
(R-HSA-916828)
0.643
3
UniProt:P67775 PPP2CA
4
MeL-PPP2CA [nucleoplasm]
(R-HSA-8857791)
p-Y307-PPP2CA [cytosol]
(R-HSA-8857939)
PPP2CA [nucleoplasm]
(R-HSA-165978)
PPP2CA [cytosol]
(R-HSA-165971)
0.643
4
UniProt:Q9P289 STK26
3
MST4(306-416) [cytosol]
(R-HSA-351903)
MST4(1-305) [cytosol]
(R-HSA-351855)
MST4 [cytosol]
(R-HSA-351918)
0.593
4
UniProt:Q9Y376 CAB39
4
CAB39 [secretory granule lumen]
(R-HSA-6801288)
CAB39 [extracellular region]
(R-HSA-6806462)
CAB39 [ficolin-1-rich granule lumen]
(R-HSA-6801287)
CAB39 [cytosol]
(R-HSA-380969)
0.544
6
UniProt:P63167 DYNLL1
6
DYNLL1 [ciliary tip]
(R-HSA-5625335)
DYNLL1 [cilium]
(R-HSA-5624863)
DYNLL1 [ficolin-1-rich granule membrane]
(R-HSA-6801518)
DYNLL1 [tertiary granule membrane]
(R-HSA-6801482)
DYNLL1 [plasma membrane]
(R-HSA-54017)
DYNLL1 [cytosol]
(R-HSA-387105)
0.527
2
UniProt:Q9NVK5 FGFR1OP2
2
FGFR1OP(1-132)-FGFR1(429-822) fusion [cytosol]
(R-HSA-1606443)
FGFR1OP(1-132)-p-FGFR1(429-822) fusion [cytosol]
(R-HSA-1838998)
0.527
2
UniProt:Q7L7X3 TAOK1
1
TAOK1 [cytosol]
(R-HSA-376248)
0.527
2
UniProt:Q9Y228 T3JAM
0.527
3
UniProt:P62714 PPP2CB
4
MeL-PPP2CB [nucleoplasm]
(R-HSA-8857799)
p-Y307-PPP2CB [cytosol]
(R-HSA-8857935)
PPP2CB [nucleoplasm]
(R-HSA-165991)
PPP2CB [cytosol]
(R-HSA-165987)
0.527
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.519
6
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text