Reactome | STK24(1-313) [cytosol]

STK24(1-313) [cytosol]

Stable Identifier

R-HSA-351892

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

MST3 fragment (1-313)

Locations in the PathwayBrowser for interactor UniProt:Q9Y228 T3JAM

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External Reference Information

External Reference

UniProt:Q9Y6E0 STK24

Gene Names

STK24, MST3, STK3

Chain

initiator methionine:, chain:1-443, chain:1-325, chain:326-443

Reference Genes

BioGPS Gene:8428 STK24

COSMIC (genes):STK24 STK24

CTD Gene:8428 STK24

dbSNP Gene:8428 STK24

ENSEMBL:ENSG00000102572 STK24

ENSEMBL:ENSG00000102572.15 STK24

HGNC:11403 STK24

KEGG Gene (Homo sapiens):8428 STK24

Monarch:8428 STK24

NCBI Gene:8428 STK24

OMIM:604984 STK24

UCSC:Q9Y6E0 STK24

Reference Transcript

Other Identifiers

11729133_a_at

11729134_s_at

11729135_a_at

11729136_a_at

1562425_PM_at

1562425_at

1562426_PM_a_at

1562426_a_at

16780456

208854_PM_s_at

208854_s_at

208855_PM_s_at

208855_s_at

3522220

3522222

3522224

3522226

3522227

3522228

3522229

3522235

3522240

3522242

3522243

3522245

3522247

3522248

3522250

3522277

3522278

3522279

3522280

3522296

3522297

4023403

4023422

40473_at

49200_at

51336_at

7972444

8428

A_23_P253177

A_23_P60683

A_24_P73389

GE54189

GE87768

GO:0000139

GO:0000166

GO:0003824

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005794

GO:0005829

GO:0006468

GO:0006915

GO:0007165

GO:0008631

GO:0009267

GO:0012501

GO:0016020

GO:0016301

GO:0016310

GO:0016740

GO:0023052

GO:0030154

GO:0030336

GO:0036211

GO:0042542

GO:0043226

GO:0045296

GO:0046777

GO:0046872

GO:0048679

GO:0048680

GO:0048856

GO:0048870

GO:0070062

GO:0097194

GO:0106310

GO:0140096

HMNXSV003046480

Hs.168913.1.A1_3p_a_at

Hs2.232864.1.A1_3p_at

Hs2.232864.1.A1_3p_x_at

ILMN_1655163

ILMN_1695773

ILMN_1702723

PH_hs_0010078

TC13000822.hg

g5326765_3p_a_at

Participates

as an input of

Nuclear translocation of catalytic domain of Mst3 (Homo sapiens)

as an output of

Caspase-mediated cleavage of MST3 (Homo sapiens)

Other forms of this molecule

STK24(1-313) [nucleoplasm]

STK24(314-443) [cytosol]

STK24 [cytosol]

Inferred To

Homologues of STK24(1-313) [cytosol] (Dictyostelium discoideum)

Homologues of STK24(1-313) [cytosol] (Schizosaccharomyces pombe)

STK24(1-313) [cytosol] (Bos taurus)

STK24(1-313) [cytosol] (Caenorhabditis elegans)

STK24(1-313) [cytosol] (Canis familiaris)

STK24(1-313) [cytosol] (Danio rerio)

STK24(1-313) [cytosol] (Dictyostelium discoideum)

STK24(1-313) [cytosol] (Drosophila melanogaster)

STK24(1-313) [cytosol] (Gallus gallus)

STK24(1-313) [cytosol] (Mus musculus)

STK24(1-313) [cytosol] (Rattus norvegicus)

STK24(1-313) [cytosol] (Saccharomyces cerevisiae)

STK24(1-313) [cytosol] (Schizosaccharomyces pombe)

STK24(1-313) [cytosol] (Sus scrofa)

STK24(1-313) [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_003567.2, NP_001027467.2

ZINC - World Drugs

STK24_HUMAN

Guide to Pharmacology - Targets

2217

OpenTargets

ENSG00000102572

ZINC - FDA approved

STK24_HUMAN

ZINC - Substances

STK24_HUMAN

ZINC target

Q9Y6E0

ZINC - Biogenic

STK24_HUMAN

PRO

Q9Y6E0

PDB

7B35, 3A7I, 4U8Z, 7B34, 4QMU, 3A7H, 4QMS, 4QMV, 3A7G, 4QMQ, 4QMW, 3A7F, 4QMP, 7B30, 4QO9, 4O27, 4QMX, 4QMO, 7B31, 4QMY, 7B32, 4QMN, 3CKX, 4QMZ, 4W8D, 7B33, 4QMM, 8BZI, 3CKW, 3A7J, 3ZHP, 4QML, 4W8E, 4QNA, 8BZJ, 4QMT

ZINC - Investigational

STK24_HUMAN

GeneCards

Q9Y6E0

HPA

ENSG00000102572-STK24

Ensembl

ENSG00000102572, ENST00000376547, ENSP00000365730, ENSP00000442539, ENST00000539966

Pharos - Targets

Q9Y6E0

ZINC - Predictions - Purchasable

STK24_HUMAN

HMDB Protein

HMDBP01373

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BUL8 PDC10			0.935	12
UniProt:Q13033 STRN3			0.84	7
UniProt:Q14BN4 SLMAP			0.802	5
UniProt:O43815 STRN	5	STRN [cytosol] (R-HSA-9037081) STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673902) p-11Y-STRN(1-265)-PDGFRA(580-1089) fusion [cytosol] (R-HSA-9673908) STRN(1-137)-ALK(1058-1620) fusion [cytosol] (R-HSA-9700485) STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9700467)	0.784	5
UniProt:P30153 PPP2R1A	2	PPP2R1A [cytosol] (R-HSA-165982) PPP2R1A [nucleoplasm] (R-HSA-165968)	0.744	4
UniProt:Q9Y3A3 PHOCN			0.744	5
UniProt:Q9NRL3 STRN4			0.744	4
UniProt:O00506 STK25			0.744	5
UniProt:Q9P2B4 CT2NL			0.708	5
UniProt:Q5VSL9 STRP1			0.669	4
UniProt:P62714 PPP2CB	4	MeL-PPP2CB [nucleoplasm] (R-HSA-8857799) p-Y307-PPP2CB [cytosol] (R-HSA-8857935) PPP2CB [nucleoplasm] (R-HSA-165991) PPP2CB [cytosol] (R-HSA-165987)	0.669	3
UniProt:Q8WZ74 CTTB2			0.643	4
UniProt:Q9NVK5 FGFR1OP2	2	FGFR1OP(1-132)-FGFR1(429-822) fusion [cytosol] (R-HSA-1606443) FGFR1OP(1-132)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1838998)	0.643	3
UniProt:P30154 PPP2R1B	2	PPP2R1B [nucleoplasm] (R-HSA-166000) PPP2R1B [cytosol] (R-HSA-165980)	0.643	3
UniProt:P67775 PPP2CA	4	MeL-PPP2CA [nucleoplasm] (R-HSA-8857791) p-Y307-PPP2CA [cytosol] (R-HSA-8857939) PPP2CA [nucleoplasm] (R-HSA-165978) PPP2CA [cytosol] (R-HSA-165971)	0.643	3
UniProt:Q9ULQ0 STRP2			0.643	3
UniProt:Q9BRV8 SIKE1	1	SIKE1 [cytosol] (R-HSA-916828)	0.643	4
UniProt:Q9P289 STK26	3	MST4(306-416) [cytosol] (R-HSA-351903) MST4(1-305) [cytosol] (R-HSA-351855) MST4 [cytosol] (R-HSA-351918)	0.643	4
UniProt:O55106	1	Strn [cytosol] (R-MMU-9037081)	0.536	3
UniProt:P63167 DYNLL1	6	DYNLL1 [ciliary tip] (R-HSA-5625335) DYNLL1 [cytosol] (R-HSA-387105) DYNLL1 [plasma membrane] (R-HSA-54017) DYNLL1 [tertiary granule membrane] (R-HSA-6801482) DYNLL1 [ficolin-1-rich granule membrane] (R-HSA-6801518) DYNLL1 [cilium] (R-HSA-5624863)	0.527	2
UniProt:Q9Y228 T3JAM			0.499	2

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