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SLC6A20 [plasma membrane]
Stable Identifier
R-HSA-352058
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Sodium- and chloride-dependent transporter XTRP3
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Na+/Cl- dependent neurotransmitter transporters (Homo sapiens)
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Homo sapiens)
SLC6A20 [plasma membrane] (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Amino acid transport across the plasma membrane (Homo sapiens)
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Homo sapiens)
SLC6A20 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NP91 SLC6A20
Gene Names
SLC6A20, SIT1, XT3, XTRP3
Chain
chain:1-592
Reference Genes
BioGPS Gene:54716 SLC6A20
COSMIC (genes):SIT1 SLC6A20
COSMIC (genes):SLC6A20 SLC6A20
CTD Gene:54716 SLC6A20
dbSNP Gene:54716 SLC6A20
ENSEMBL:ENSG00000163817 SLC6A20
HGNC:30927 SLC6A20
KEGG:hsa:54716 SLC6A20
Monarch:54716 SLC6A20
NCBI Gene:54716 SLC6A20
OMIM:605616 SLC6A20
UCSC:Q9NP91 SLC6A20
Reference Transcript
RefSeq:NM_022405.3 SLC6A20
RefSeq:NM_020208.3 SLC6A20
Other Identifiers
11737094_a_at
11740854_a_at
16952797
219614_PM_s_at
219614_s_at
234291_PM_s_at
234291_s_at
2671937
2671938
2671939
2671940
2671941
2671943
2671946
2671948
2671949
2671950
2671951
2671952
2671953
2671954
2671956
2671959
2671960
2671961
2671963
2671964
2671965
2671966
2671967
54716
8086540
A_23_P212379
A_24_P20369
A_24_P371331
GE573893
GO:0003013
GO:0005215
GO:0005298
GO:0005515
GO:0005886
GO:0006865
GO:0015171
GO:0015175
GO:0015188
GO:0015193
GO:0015199
GO:0015293
GO:0015370
GO:0015816
GO:0015824
GO:0015838
GO:0016020
GO:0016324
GO:0022857
GO:0035725
GO:0055085
GO:0089718
GO:0150104
GO:1903804
GO:1903806
GO:1904271
GO:1905647
HMNXSV003035038
Hs.107854.2.A1_3p_a_at
ILMN_1687986
ILMN_1698585
ILMN_2324109
PH_hs_0024931
TC03001351.hg
g11181769_3p_a_at
Other forms of this molecule
SLC6A20 T199M [plasma membrane]
Inferred To
Homologues of SLC6A20 [plasma membrane]
(Drosophila melanogaster)
Homologues of SLC6A20 [plasma membrane]
(Plasmodium falciparum)
SLC6A20 [plasma membrane]
(Bos taurus)
SLC6A20 [plasma membrane]
(Canis familiaris)
SLC6A20 [plasma membrane]
(Drosophila melanogaster)
SLC6A20 [plasma membrane]
(Gallus gallus)
SLC6A20 [plasma membrane]
(Plasmodium falciparum)
SLC6A20 [plasma membrane]
(Sus scrofa)
SLC6A20 [plasma membrane]
(Xenopus tropicalis)
Slc6a20 [plasma membrane]
(Rattus norvegicus)
Slc6a20a [plasma membrane]
(Mus musculus)
Cross References
Guide to Pharmacology - Targets
944
OpenTargets
ENSG00000163817
ENSEMBL
ENSP00000346298
,
ENST00000353278
,
ENSP00000296133
,
ENST00000358525
HPA
ENSG00000163817-SLC6A20
PRO
Q9NP91
Pharos - Targets
Q9NP91
Orphanet
SLC6A20
GlyGen
Q9NP91
PDB
8P30
,
8P31
,
8P2X
,
8P2W
,
8P2Y
,
7Y75
,
8P2Z
,
7Y76
,
8I91
HMDB Protein
HMDBP07987
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P60410 KRTAP10-8
1
KRTAP10-8 [cytosol]
(R-HSA-6810301)
0.718
6
UniProt:P60370 KRTAP10-5
1
KRTAP10-5 [cytosol]
(R-HSA-6810260)
0.556
3
UniProt:A8MQ03 CRTP1
0.556
3
UniProt:P60409 KRTAP10-7
1
KRTAP10-7 [cytosol]
(R-HSA-6810279)
0.556
3
IntAct:EBI-10173330 386677
0.556
3
UniProt:Q07627 KRTAP1-1
1
KRTAP1-1 [cytosol]
(R-HSA-6809855)
0.556
3
UniProt:Q7Z3S9 NOTCH2NLA
3
NOTCH2NLA [extracellular region]
(R-HSA-9908935)
NOTCH2NLA(1-?) [extracellular region]
(R-HSA-9911493)
NOTCH2NLA(?-236) [extracellular region]
(R-HSA-9911490)
0.556
3
UniProt:P0DPK4 NOTCH2NLC
1
NOTCH2NLC [extracellular region]
(R-HSA-9908932)
0.556
3
UniProt:P60411 KRTAP10-9
1
KRTAP10-9 [cytosol]
(R-HSA-6810277)
0.556
3
IntAct:EBI-10171679 386682
0.556
3
UniProt:Q6UY14-3 ADAMTSL4
0.556
3
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