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SLC1A5 [plasma membrane]
Stable Identifier
R-HSA-352376
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
ASCT2
Locations in the PathwayBrowser for interactor UniProt:Q99942 RNF5
Expand all
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Amino acid transport across the plasma membrane (Homo sapiens)
SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Homo sapiens)
SLC1A5 [plasma membrane] (Homo sapiens)
SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Homo sapiens)
SLC1A5 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15758 SLC1A5
Gene Names
SLC1A5, ASCT2, M7V1, RDR, RDRC
Chain
chain:1-541
Reference Genes
BioGPS Gene:6510 SLC1A5
COSMIC (genes):SLC1A5 SLC1A5
CTD Gene:6510 SLC1A5
dbSNP Gene:6510 SLC1A5
ENSEMBL:ENSG00000105281 SLC1A5
ENSEMBL_homo_sapiens_GENE:ENSG00000105281.12 SLC1A5
HGNC:10943 SLC1A5
KEGG Gene (Homo sapiens):6510 SLC1A5
Monarch:6510 SLC1A5
NCBI Gene:6510 SLC1A5
OMIM:109190 SLC1A5
UCSC:Q15758 SLC1A5
Reference Transcript
RefSeq:NM_001145144.1 SLC1A5
RefSeq:NM_005628.2 SLC1A5
RefSeq:NM_001145145.1 SLC1A5
Other Identifiers
11716865_a_at
11716866_x_at
11740714_a_at
16873632
208916_PM_at
208916_at
3866277
3866278
3866279
3866280
3866281
3866282
3866283
3866284
3866285
3866286
3866289
3866290
3866291
3866292
3866294
3866295
3866296
3866297
3866298
3866299
3866300
3866301
41778_at
6510
8037835
GE62526
GE84300
GO:0001618
GO:0002376
GO:0003013
GO:0005215
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0006865
GO:0006868
GO:0009925
GO:0010585
GO:0015171
GO:0015175
GO:0015179
GO:0015183
GO:0015186
GO:0015194
GO:0015293
GO:0015297
GO:0015804
GO:0015825
GO:0016020
GO:0022834
GO:0030154
GO:0030218
GO:0031410
GO:0038023
GO:0042470
GO:0043226
GO:0046718
GO:0046872
GO:0048856
GO:0055085
GO:0060089
GO:0065003
GO:0070062
GO:0070207
GO:0140009
GO:0150104
GO:1903803
HMNXSV003014972
HMNXSV003053880
ILMN_1707720
PH_hs_0010825
TC19001656.hg
U53347_at
g4191561_3p_at
g4191561_3p_x_at
Participates
as a candidate of
RHOQ effectors [cytosol] (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
Inferred To
Eaat1 [plasma membrane]
(Drosophila melanogaster)
glt-1 [plasma membrane]
(Caenorhabditis elegans)
slc1a5 [plasma membrane]
(Danio rerio)
slc1a5 [plasma membrane]
(Xenopus tropicalis)
glt-5 [plasma membrane]
(Caenorhabditis elegans)
glt-7 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC1A5 [plasma membrane]
(Caenorhabditis elegans)
SLC1A5 [plasma membrane]
(Bos taurus)
SLC1A5 [plasma membrane]
(Caenorhabditis elegans)
SLC1A5 [plasma membrane]
(Canis familiaris)
SLC1A5 [plasma membrane]
(Mus musculus)
SLC1A5 [plasma membrane]
(Rattus norvegicus)
SLC1A5 [plasma membrane]
(Sus scrofa)
glt-3 [plasma membrane]
(Caenorhabditis elegans)
glt-6 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001138617.1
,
NP_005619.1
,
NP_001138616.1
Guide to Pharmacology - Targets
874
OpenTargets
ENSG00000105281
GeneCards
Q15758
HPA
ENSG00000105281-SLC1A5
Ensembl
ENST00000542575
,
ENSP00000406532
,
ENSG00000105281
,
ENSP00000397924
,
ENST00000412532
,
ENSP00000444408
,
ENST00000434726
PRO
Q15758
Pharos - Targets
Q15758
HMDB Protein
HMDBP01955
PDB
5LLU
,
6RVY
,
7BCQ
,
7BCT
,
6GCT
,
6RVX
,
6MP6
,
5LM4
,
7BCS
,
6MPB
,
5LLM
,
5MJU
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99942 RNF5
1
RNF5 [endoplasmic reticulum membrane]
(R-HSA-975990)
0.576
4
UniProt:O95236-2 APOL3
0.556
3
UniProt:P60201-2 PLP1
0.556
3
UniProt:A5PKU2 A5PKU2
0.556
3
UniProt:O75110 ATP9A
1
ATP9A [plasma membrane]
(R-HSA-939754)
0.527
2
UniProt:Q9NRX5 SERINC1
1
SERINC1 [plasma membrane]
(R-HSA-5215963)
0.527
2
UniProt:Q9NUE0 ZDH18
0.527
2
UniProt:Q6Y1H2 HACD2
1
PTPLB [endoplasmic reticulum membrane]
(R-HSA-5676075)
0.527
2
UniProt:Q96AG3 S2546
0.527
2
UniProt:P0DTC5 M
10
M [plasma membrane]
(R-COV-9755780)
N-glycan M [virion membrane]
(R-COV-9694385)
M [virion membrane]
(R-COV-9694320)
M [endocytic vesicle membrane]
(R-COV-9694563)
N-glycan M [endocytic vesicle membrane]
(R-COV-9694738)
M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694439)
N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694446)
M [endoplasmic reticulum membrane]
(R-COV-9767620)
nascent M [endoplasmic reticulum lumen]
(R-COV-9694279)
N-glycan M [endoplasmic reticulum membrane]
(R-COV-9694684)
0.527
2
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