LYN [cytosol]

Stable Identifier
R-HSA-354251
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Tyrosine-protein kinase LYN, LYN_HUMAN
Icon
LYN [cytosol] icon
LYN [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P07948 LYN
Gene Names
LYN, JTK8
Chain
initiator methionine:1, chain:2-512
Reference Genes
BioGPS Gene:4067 LYN
COSMIC (genes):LYN LYN
CTD Gene:4067 LYN
dbSNP Gene:4067 LYN
ENSEMBL:ENSG00000254087.8 LYN
HGNC:6735 LYN
KEGG Gene (Homo sapiens):4067 LYN
Monarch:4067 LYN
NCBI Gene:4067 LYN
OMIM:165120 LYN
UCSC:P07948 LYN
Reference Transcript
Other Identifiers
11718084_a_at
11718085_s_at
11732514_s_at
1402_at
17069063
2024_s_at
202625_PM_at
202625_at
202626_PM_s_at
202626_s_at
210754_PM_s_at
210754_s_at
3098978
3098979
3098997
3098998
3098999
3099000
3099001
3099002
3099005
3099006
3099007
3099010
3099011
3099024
3099026
3099028
3099029
3099030
3099050
32616_at
4067
54933_at
77231_at
8146500
A_14_P123503
A_23_P147431
GE57840
GO:0000166
GO:0001782
GO:0001817
GO:0001932
GO:0001933
GO:0001934
GO:0002223
GO:0002244
GO:0002250
GO:0002376
GO:0002431
GO:0002513
GO:0002553
GO:0002576
GO:0002762
GO:0002768
GO:0002774
GO:0002862
GO:0002902
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005102
GO:0005161
GO:0005178
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005739
GO:0005758
GO:0005764
GO:0005765
GO:0005773
GO:0005794
GO:0005829
GO:0005886
GO:0005912
GO:0006468
GO:0006629
GO:0006954
GO:0006974
GO:0006991
GO:0007155
GO:0007165
GO:0007169
GO:0008092
GO:0008284
GO:0008285
GO:0008289
GO:0009410
GO:0009636
GO:0009725
GO:0009743
GO:0010976
GO:0012501
GO:0014003
GO:0014069
GO:0014070
GO:0016020
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0017124
GO:0018108
GO:0019899
GO:0023052
GO:0030061
GO:0030097
GO:0030154
GO:0030218
GO:0030335
GO:0030666
GO:0030889
GO:0031175
GO:0031234
GO:0031295
GO:0031410
GO:0031625
GO:0031663
GO:0031668
GO:0031966
GO:0032868
GO:0032991
GO:0033003
GO:0033628
GO:0034136
GO:0034142
GO:0034144
GO:0034605
GO:0034666
GO:0035556
GO:0036211
GO:0038095
GO:0038096
GO:0038159
GO:0042060
GO:0042327
GO:0042531
GO:0043015
GO:0043200
GO:0043208
GO:0043226
GO:0043231
GO:0043304
GO:0043407
GO:0043434
GO:0043552
GO:0044325
GO:0044877
GO:0045087
GO:0045121
GO:0045646
GO:0046777
GO:0046875
GO:0048013
GO:0048471
GO:0048678
GO:0048856
GO:0048870
GO:0050727
GO:0050777
GO:0050853
GO:0050855
GO:0050900
GO:0051219
GO:0051279
GO:0055065
GO:0055085
GO:0060252
GO:0060369
GO:0060397
GO:0070062
GO:0070304
GO:0070372
GO:0070373
GO:0070447
GO:0070667
GO:0070668
GO:0071300
GO:0090025
GO:0090330
GO:0097028
GO:0097110
GO:0098542
GO:0098978
GO:0099091
GO:0140031
GO:0140096
GO:1902532
GO:1902961
GO:2000670
HMNXSV003009154
Hs.80887.0.A2_3p_at
ILMN_1781155
M16038_at
PH_hs_0004647
TC08000383.hg
g187270_3p_a_at
g4505054_3p_a_at
Participates
as a component of
as an input of
as a member of
as a candidate of
Other forms of this molecule
MyrG2-PalmC3-LYN [lysosomal membrane]
MyrG2-PalmC3-LYN [endocytic vesicle membrane]
LYN [plasma membrane]
p-Y397-LYN [cytosol]
p-Y397-LYN [plasma membrane]
MyrG2-PalmC3-LYN [plasma membrane]
Inferred To
Lyn [cytosol] (Mus musculus)
Lyn [cytosol] (Rattus norvegicus)
Ghost homologue of LYN [cytosol] (Danio rerio)
LYN [cytosol] (Bos taurus)
LYN [cytosol] (Caenorhabditis elegans)
LYN [cytosol] (Canis familiaris)
LYN [cytosol] (Drosophila melanogaster)
LYN [cytosol] (Gallus gallus)
LYN [cytosol] (Sus scrofa)
LYN [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
PDB
ZINC - Investigational
IntEnz
GeneCards
HPA
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (42)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P00533 EGFR  20 0.82 7
 UniProt:P27958 Genome polyprotein  1 0.704 4
 UniProt:P12931 SRC  6 0.669 4
 UniProt:Q9WMX2 POLG      0.667 3
 UniProt:Q9NWQ8 PAG1  2 0.641 16
 UniProt:Q9HCN6 GP6  1 0.641 5
 UniProt:Q07666 KHDRBS1  3 0.609 2
 UniProt:Q13444 ADAM15  1 0.609 2
 UniProt:Q8NDB2 BANK1      0.591 3
 UniProt:O92972 POLG      0.589 2
 UniProt:Q05397 PTK2  11 0.573 2
 UniProt:P22681 CBL  20 0.564 2
 UniProt:P08238 HSP90AB1  6 0.564 2
 UniProt:P22575 TIP      0.558 3
 UniProt:Q8R5G7  1 0.558 2
 UniProt:O43184 ADAM12  1 0.558 2
 UniProt:P37840 SNCA  4 0.556 3
 UniProt:Q7Z699 SPRED1  2 0.556 3
 UniProt:P50570-2 DNM2      0.556 3
 UniProt:P51608 MECP2      0.556 3
 UniProt:Q96L34 MARK4  1 0.556 3
 UniProt:Q96GW7 BCAN  20 0.556 3
 UniProt:P01023 A2M  2 0.556 3
 UniProt:P07602 PSAP  7 0.556 3
 UniProt:P05067 APP  20 0.556 3
 UniProt:P27986-2 PIK3R1      0.556 3
 UniProt:Q9BS26 ERP44  2 0.556 3
 UniProt:P46527 CDKN1B  8 0.544 2
 UniProt:P06239 LCK  4 0.527 2
 UniProt:P09769 FGR  3 0.527 3
 UniProt:P08631 HCK  2 0.527 3
 UniProt:Q9HCN6-1 GP6      0.524 2
 UniProt:Q15642 TRIP10  1 0.508 2
 UniProt:P25063 CD24  1 0.499 6
 UniProt:P16671 CD36  5 0.499 3
 UniProt:P33993 MCM7  1 0.499 4
 UniProt:Q6UWF3 SCIMP      0.499 3
 UniProt:Q08857 Cd36  6 0.499 2
 UniProt:P11049 CD37      0.499 5
 UniProt:P14317 HCLS1      0.499 2
 UniProt:P20273 CD22  3 0.499 2
 UniProt:P61980  2 0.469 2
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