Nephrin binds CASK

Stable Identifier
R-HSA-373722
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Nephrin binds CASK
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CASK is a scaffolding protein that participates in maintenance of polarized epithelial cell architecture by linking membrane proteins and signaling molecules to the actin cytoskeleton. CASK is identified as one of the binding partners of nephrin and this interaction likely plays an important role in establishing the structural integrity and functional properties of the glomerular slit diaphragm.
Participants
Input
Output
Entity On Other Cell
Participates
as an event of
Inferred From
Nephrin binds Cask (Rattus norvegicus)
Authored
Garapati, P V  (2008-02-26)
de Bono, B  (2008-02-26)
Reviewed
Grahammer, Florian  (2010-05-20)
Huber, TB  (2010-05-20)
Created
Garapati, P V  (2008-07-16)
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