Shootin-1 links L1 and retrograde actin flow

Stable Identifier
R-HSA-373736
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Shootin-1 links L1 and retrograde actin flow
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Shootin-1 acts as a linker protein, binding L1 to moving actin filaments in axonal growth cones. This interaction mediates the migration of L1 on the plasma membrane from P-domain to the C-domain of the growth cone and enhances neurite elongation.
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Inferred From
Shootin-1 links L1 and retrograde actin flow (Rattus norvegicus)
Authored
Garapati, P V  (2008-07-30)
Reviewed
Maness, PF  (2010-02-16)
Created
Garapati, P V  (2008-07-16)
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