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DCC interaction with Ezrin
Stable Identifier
R-HSA-374663
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Netrin-1 signaling (Homo sapiens)
DCC interaction with Ezrin (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Phosphorylated Ezrin can link in microfilaments to the plasma membrane by direct association with transmembrane proteins such as the cytoplasmic domain of DCC.
Literature References
PubMed ID
Title
Journal
Year
16762451
DCC regulates cell adhesion in human colon cancer derived HT-29 cells and associates with ezrin
Real, FX
,
Mangeat, P
,
Kedinger, M
,
Simon-Assmann, P
,
Martin, M
,
Martin, M
,
Fabre, M
Eur J Cell Biol
2006
Participants
Input
DCC [plasma membrane]
(Homo sapiens)
p-T567-EZR:PIP2 [plasma membrane]
(Homo sapiens)
Output
DCC:p-T567-EZR:PIP2 [plasma membrane]
(Homo sapiens)
Participates
as an event of
Netrin-1 signaling (Homo sapiens)
Orthologous Events
DCC interaction with Ezrin (Bos taurus)
DCC interaction with Ezrin (Caenorhabditis elegans)
DCC interaction with Ezrin (Canis familiaris)
DCC interaction with Ezrin (Danio rerio)
DCC interaction with Ezrin (Drosophila melanogaster)
DCC interaction with Ezrin (Mus musculus)
DCC interaction with Ezrin (Rattus norvegicus)
DCC interaction with Ezrin (Sus scrofa)
DCC interaction with Ezrin (Xenopus tropicalis)
Authored
Garapati, P V (2008-07-16)
Reviewed
Cooper, HM (2010-02-16)
Created
Garapati, P V (2008-07-30)
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