Phosphorylation of L1 by p90rsk

Stable Identifier
R-HSA-374696
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Phosphorylation of L1 by p90rsk
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

p90rsk associates with the internalized L1 in the endosomes and phosphorylates it at Ser1152. This phosphorylation may regulate the interactions of L1 and intracellular signaling cascades or cytoskeletal elements involved in neurite outgrowth on specific substrates.

Participants
Input
Output
Participates
as an event of
Catalyst Activity

protein serine/threonine kinase activity of p90rsk [cytosol]

Physical Entity
p90rsk [cytosol] (Homo sapiens)
Activity
protein serine/threonine kinase activity (GO:0004674)
Inferred From
Phosphorylation of L1 by p90rsk (Homo sapiens)
Authored
Garapati, P V  (2008-07-30)
Reviewed
Maness, PF  (2010-02-16)
Created
Garapati, P V  (2008-07-30)
Cite Us!