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NMB(47-56) [extracellular region]
Stable Identifier
R-HSA-375361
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Neuromedin-B, NMB_HUMAN, NMB
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like peptide [extracellular region] (Homo sapiens)
NMB(47-56) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like peptide [extracellular region] (Homo sapiens)
NMB(47-56) [extracellular region] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like peptide [extracellular region] (Homo sapiens)
NMB(47-56) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like peptide [extracellular region] (Homo sapiens)
NMB(47-56) [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like peptide [extracellular region] (Homo sapiens)
NMB(47-56) [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
Bombesin-like peptide [extracellular region] (Homo sapiens)
NMB(47-56) [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Bombesin-like receptors bind bombesin homologues (Homo sapiens)
Bombesin-like peptide [extracellular region] (Homo sapiens)
NMB(47-56) [extracellular region] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like peptide [extracellular region] (Homo sapiens)
NMB(47-56) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08949 NMB
Gene Names
NMB
Chain
signal peptide:1-24, peptide:25-56, peptide:47-56, propeptide:60-121
Reference Genes
BioGPS Gene:4828 NMB
COSMIC (genes):NMB NMB
CTD Gene:4828 NMB
dbSNP Gene:4828 NMB
ENSEMBL:ENSG00000197696 NMB
ENSEMBL_homo_sapiens_GENE:ENSG00000197696.10 NMB
ENSEMBL_homo_sapiens_GENE:ENSG00000291631.1 NMB
HGNC:7842 NMB
KEGG Gene (Homo sapiens):4828 NMB
Monarch:4828 NMB
NCBI Gene:4828 NMB
OMIM:162340 NMB
UCSC:P08949 NMB
Reference Transcript
RefSeq:NM_021077.3 NMB
RefSeq:NM_205858.1 NMB
Other Identifiers
11721357_at
16812824
205204_PM_at
205204_at
3636986
3636987
3636988
3636993
3636994
3636999
3637000
3637001
40686_at
4828
7991138
89861_at
A_23_P88522
GE62256
GO:0002376
GO:0005179
GO:0005184
GO:0005515
GO:0005576
GO:0005615
GO:0007165
GO:0007204
GO:0007218
GO:0007267
GO:0008284
GO:0023052
GO:0031710
GO:0032715
GO:0032727
GO:0042995
GO:0043005
GO:0045087
GO:0046887
GO:0046888
GO:0048018
GO:0050482
GO:0050877
GO:0090290
GO:0098542
GO:0098772
GO:0140374
GO:0160023
GO:0160024
GO:0160025
GO:1903942
GO:2000845
HMNXSV003002378
ILMN_2347592
M21551_rna1_at
PH_hs_0024396
TC15001787.hg
g10835106_3p_at
Participates
as a member of
Bombesin-like peptide [extracellular region] (Homo sapiens)
Inferred To
Nmb [extracellular region]
(Mus musculus)
Nmb [extracellular region]
(Rattus norvegicus)
LOC569893 [extracellular region]
(Danio rerio)
NMB [extracellular region]
(Canis familiaris)
NMB [extracellular region]
(Gallus gallus)
NMB [extracellular region]
(Sus scrofa)
Cross References
RefSeq
NP_995580.1
,
NP_066563.2
OpenTargets
ENSG00000197696
GeneCards
P08949
HPA
ENSG00000197696-NMB
Ensembl
ENSP00000378089
,
ENSP00000353664
,
ENST00000394588
,
ENSG00000197696
,
ENST00000360476
PRO
P08949
Pharos - Targets
P08949
PDB
1C9A
,
1C98
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13490 BIRC2
5
K63polyUb-BIRC2 [cytosol]
(R-HSA-5668512)
BIRC2(1-372) [cytosol]
(R-HSA-202913)
BIRC2(373-618) [cytosol]
(R-HSA-202931)
K48pUb-BIRC2 [cytosol]
(R-HSA-5675479)
BIRC2 [cytosol]
(R-HSA-50847)
0.556
3
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