Reactome | NR1D2 [nucleoplasm]

NR1D2 [nucleoplasm]

Stable Identifier

R-HSA-375501

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

NR1D2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q14995 NR1D2

Gene Names

NR1D2

Chain

chain:1-579

Reference Genes

BioGPS Gene:9975 NR1D2

COSMIC (genes):NR1D2 NR1D2

CTD Gene:9975 NR1D2

dbSNP Gene:9975 NR1D2

ENSEMBL:ENSG00000174738.13 NR1D2

HGNC:7963 NR1D2

KEGG Gene (Homo sapiens):9975 NR1D2

Monarch:9975 NR1D2

NCBI Gene:9975 NR1D2

OMIM:602304 NR1D2

UCSC:Q14995 NR1D2

Reference Transcript

RefSeq:NM_005126.4 NR1D2

Other Identifiers

0005340364

11722087_a_at

11722088_s_at

11742029_a_at

11751940_a_at

16938378

209750_PM_at

209750_at

225768_PM_at

225768_at

2614144

2614145

2614151

2614152

2614153

2614154

2614155

2614157

2614159

2614165

2614166

2614167

2614168

2614169

35705_at

35706_at

45121_at

8078272

9975

A_14_P103251

A_23_P302709

A_24_P943472

A_33_P3409124

D16815_at

GE550510

GE86202

GE86203

GO:0000122

GO:0000785

GO:0000978

GO:0000981

GO:0000987

GO:0001227

GO:0003677

GO:0003700

GO:0004879

GO:0005515

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0006351

GO:0006355

GO:0006629

GO:0006954

GO:0008270

GO:0009755

GO:0019216

GO:0023052

GO:0030154

GO:0030522

GO:0042752

GO:0043226

GO:0043565

GO:0045892

GO:0045893

GO:0045944

GO:0046872

GO:0048511

GO:0048512

GO:0048856

GO:0050727

GO:0050728

GO:0055088

GO:0060089

GO:0097009

GO:1990837

GO:2001014

HMNXSV003031795

HMNXSV003051870

Hs.277585.1.S1_3p_at

Hs.37288.0.S2_3p_at

ILMN_1676844

ILMN_1698668

ILMN_1704471

PH_hs_0002946

TC03000127.hg

Participates

as a member of

NR [nucleoplasm] (Homo sapiens)

Inferred To

Homologues of NR1D2 [nucleoplasm] (Caenorhabditis elegans)

nhr-2 [nucleoplasm] (Caenorhabditis elegans)

nr1d2 [nucleoplasm] (Xenopus tropicalis)

Eip75B [nucleoplasm] (Drosophila melanogaster)

NR1D2 [nucleoplasm] (Bos taurus)

NR1D2 [nucleoplasm] (Canis familiaris)

NR1D2 [nucleoplasm] (Gallus gallus)

NR1D2 [nucleoplasm] (Mus musculus)

NR1D2 [nucleoplasm] (Rattus norvegicus)

NR1D2 [nucleoplasm] (Sus scrofa)

nhr-7 [nucleoplasm] (Caenorhabditis elegans)

reverbb2 [nucleoplasm] (Danio rerio)

nhr-85 [nucleoplasm] (Caenorhabditis elegans)

sex-1 [nucleoplasm] (Caenorhabditis elegans)

unc-55 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_005117.3

Guide to Pharmacology - Targets

597

OpenTargets

ENSG00000174738

ZINC - Substances

NR1D2_HUMAN

ZINC target

Q14995

PRO

Q14995

PDB

6WMS, 2V7C, 3CQV, 4N73, 6WMQ, 2V0V

HPA

ENSG00000174738-NR1D2

GeneCards

Q14995

Ensembl

ENST00000312521, ENSG00000174738, ENSP00000310006

Pharos - Targets

Q14995

Orphanet

24764

ZINC - Predictions - Purchasable

NR1D2_HUMAN

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P04792 HSPB1	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.556	3
UniProt:P06396 GSN	7	GSN(200-270) [extracellular region] (R-HSA-976940) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:O15354 GPR37	1	GPR37 [plasma membrane] (R-HSA-5333623)	0.556	3
UniProt:O08785 Clock	2	Clock [cytosol] (R-MMU-508720) p-S-Clock [nucleoplasm] (R-MMU-508670)	0.508	2
UniProt:Q96LA8 PRMT6	1	PRMT6 [nucleoplasm] (R-HSA-5226884)	0.508	2