Reactome | SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids

SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids

Stable Identifier

R-HSA-375768

Type

Reaction [transition]

Species

Homo sapiens

Compartment

plasma membrane

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

SLC7A2, isoform B, mediates the uptake of cationic amino acids across the plasma membranes of non-epithelial cells (Broer 2008; Closs et al. 1997; Furesz et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
18195088	Amino acid transport across mammalian intestinal and renal epithelia Broer, S	Physiol Rev	2008
9174363	Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties Closs, EI, Graf, P, Habermeier, A, Cunningham, JM, Forstermann, U	Biochemistry	1997
12202949	Lysine uptake by cloned hCAT-2B: comparison with hCAT-1 and with trophoblast surface membranes Furesz, TC, Heath-Monnig, E, Kamath, SG, Smith, CH	J Membr Biol	2002