Reactome | AHCTF1 [cytosol]

AHCTF1 [cytosol]

Stable Identifier

R-HSA-376244

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

MEL-28, ELYS, Embryonic large molecule derived from yolk sac

Locations in the PathwayBrowser for interactor UniProt:P57740 NUP107

Expand all

External Reference Information

External Reference

UniProt:Q8WYP5 AHCTF1

Gene Names

AHCTF1, ELYS, TMBS62, MSTP108

Chain

chain:1-2266

Reference Genes

BioGPS Gene:25909 AHCTF1

COSMIC (genes):AHCTF1 AHCTF1

CTD Gene:25909 AHCTF1

dbSNP Gene:25909 AHCTF1

ENSEMBL:ENSG00000153207 AHCTF1

HGNC:24618 AHCTF1

KEGG:hsa:25909 AHCTF1

Monarch:25909 AHCTF1

NCBI Gene:25909 AHCTF1

OMIM:610853 AHCTF1

UCSC:Q8WYP5 AHCTF1

Reference Transcript

Other Identifiers

11730252_s_at

11730253_a_at

1560224_PM_at

1560224_at

16701440

214766_PM_s_at

214766_s_at

226115_PM_at

226115_at

2465325

2465326

2465327

2465328

2465329

2465330

2465331

2465334

2465335

2465336

2465337

2465338

2465340

2465342

2465344

2465345

2465346

2465347

2465348

2465349

2465350

2465351

2465356

2465357

2465358

2465360

2465361

2465362

2465363

2465364

2465366

2465367

2465368

2465369

2465370

2465371

2465372

2465373

2465374

2465375

2465376

2465377

2465378

2465379

2465381

2465383

2465384

2465385

2465387

2465388

2465389

2465390

2465391

2465392

2465394

2583929

2583931

2583933

2583934

2583935

2583936

2583937

2583943

2583945

2583947

2583949

2583951

2583955

2583956

2583957

2583958

2583959

2583960

2583961

2583962

2583963

2583965

2583967

2583969

2583971

2583973

2583975

2583977

2583979

2583981

2583983

2583985

2583987

2583989

25909

35672_at

61864_at

7925622

8056220

A_23_P63584

A_24_P28657

A_32_P157228

A_33_P3666346

GE56349

GO:0000775

GO:0000776

GO:0000785

GO:0003677

GO:0005634

GO:0005635

GO:0005643

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0006913

GO:0015031

GO:0016363

GO:0016604

GO:0031080

GO:0031965

GO:0032465

GO:0043226

GO:0051028

GO:0051292

GO:0051301

GO:0065003

GO:0070062

HMNXSV003018144

Hs.33363.0.A2_3p_at

Hs.33363.1.S1_3p_a_at

Hs2.433190.1.S1_3p_at

ILMN_1666679

ILMN_1747504

ILMN_1809139

PH_hs_0028849

PH_hs_0038407

TC01004062.hg

TC02002477.hg

Participates

as a component of

as an input of

AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Homo sapiens)

Inferred To

AHCTF1 [cytosol] (Bos taurus)

AHCTF1 [cytosol] (Canis familiaris)

AHCTF1 [cytosol] (Gallus gallus)

AHCTF1 [cytosol] (Sus scrofa)

Ahctf1 [cytosol] (Mus musculus)

Ahctf1 [cytosol] (Rattus norvegicus)

Elys [cytosol] (Drosophila melanogaster)

ahctf1 [cytosol] (Danio rerio)

ahctf1 [cytosol] (Xenopus tropicalis)

Ghost homologue of AHCTF1 [cytosol] (Dictyostelium discoideum)

Ghost homologue of AHCTF1 [cytosol] (Schizosaccharomyces pombe)

srap-1 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

XP_006711821.1, NP_001310271.1, NP_056261.4, NP_001397879.1

ENSEMBL

ENST00000326225, ENSP00000355464, ENSP00000355465, ENSP00000497061, ENST00000648844, ENSG00000153207, ENST00000366508

OpenTargets

ENSG00000153207

GeneCards

AHCTF1

HPA

ENSG00000153207-AHCTF1

PRO

Q8WYP5

Pharos - Targets

Q8WYP5

GlyGen

Q8WYP5

PDB

7R5K, 7R5J

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8NFH4 NUP37	2	NUP37 [nuclear envelope] (R-HSA-157745) NUP37 [cytosol] (R-HSA-376237)	0.621	3
UniProt:Q9BW27 NUP85	2	NUP85 [nuclear envelope] (R-HSA-157741) NUP85 [cytosol] (R-HSA-376238)	0.57	4
UniProt:Q6PFD9	9	phospho-Nup98 [cytosol] (R-MMU-2990915) phospho-Nup98 [cytosol] (R-MMU-2990893) phospho-Nup98 [nucleoplasm] (R-MMU-2990884) phospho-Nup98 [nucleoplasm] (R-MMU-2990914) phospho-Nup98 [nuclear envelope] (R-MMU-2990895) phospho-Nup98 [nuclear envelope] (R-MMU-2990916) Nup98 [nuclear envelope] (R-MMU-2990912) Nup98 [nuclear envelope] (R-MMU-157723) Nup98 [cytosol] (R-MMU-376247)	0.564	2
UniProt:Q12769 NUP160	2	NUP160 [nuclear envelope] (R-HSA-157721) NUP160 [cytosol] (R-HSA-376253)	0.488	3
UniProt:Q8NFH3 NUP43	2	NUP43 [nuclear envelope] (R-HSA-157739) NUP43 [cytosol] (R-HSA-376243)	0.488	3
UniProt:P57740 NUP107	2	NUP107 [nuclear envelope] (R-HSA-157717) NUP107 [cytosol] (R-HSA-376241)	0.488	3
UniProt:Q8WUM0 NUP133	2	NUP133 [nuclear envelope] (R-HSA-157743) NUP133 [cytosol] (R-HSA-376251)	0.488	3
UniProt:Q96EE3 SEH1L	1	SEH1L [lysosomal membrane] (R-HSA-9638217)	0.488	3
UniProt:P52948-PRO_0000019930 NUP98			0.488	3
UniProt:P06748 NPM1	11	NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [granular component] (R-HSA-9017702) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.483	2

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