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CBY1 [nucleoplasm]
Stable Identifier
R-HSA-3769210
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
ARB1, CBY, PGEA1, C22orf2
Locations in the PathwayBrowser for interactor UniProt:Q6BDS2 BLT3A
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Deactivation of the beta-catenin transactivating complex (Homo sapiens)
CBY1 binds beta-catenin (Homo sapiens)
CBY1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y3M2 CBY1
Gene Names
CBY1, ARB1, C22orf2, CBY, PGEA1, HRIHFB2025
Chain
chain:1-126
Reference Genes
BioGPS Gene:25776 CBY1
COSMIC (genes):CBY1 CBY1
CTD Gene:25776 CBY1
dbSNP Gene:25776 CBY1
ENSEMBL:ENSG00000100211 CBY1
ENSEMBL_homo_sapiens_GENE:ENSG00000100211.12 CBY1
HGNC:1307 CBY1
KEGG Gene (Homo sapiens):25776 CBY1
Monarch:25776 CBY1
NCBI Gene:25776 CBY1
OMIM:607757 CBY1
UCSC:Q9Y3M2 CBY1
Reference Transcript
RefSeq:NM_015373.3 CBY1
RefSeq:NM_001002880.1 CBY1
Other Identifiers
11719193_a_at
16930077
203450_PM_at
203450_at
25776
33406_at
3945350
3945351
3945352
3945354
3945355
3945357
3945358
3945362
3945363
3945368
3945369
3945370
8073022
A_24_P74571
GE62096
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005794
GO:0005802
GO:0005814
GO:0005815
GO:0005829
GO:0005856
GO:0005929
GO:0006351
GO:0006355
GO:0008013
GO:0008104
GO:0016607
GO:0023052
GO:0030030
GO:0030154
GO:0030178
GO:0033504
GO:0036064
GO:0042802
GO:0042803
GO:0042995
GO:0043226
GO:0044782
GO:0045444
GO:0045892
GO:0048856
GO:0051289
GO:0055007
GO:0060070
GO:0060271
GO:0065003
GO:0090090
HMNXSV003014044
ILMN_1678484
ILMN_1730879
ILMN_2399571
PH_hs_0023862
g7656941_3p_at
Participates
as an input of
CBY1 binds beta-catenin (Homo sapiens)
as a component of
CBY1:CTNNB1 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
pS20-CBY1 [nucleoplasm]
pS20-CBY1 [cytosol]
Inferred To
cby1 [nucleoplasm]
(Danio rerio)
cby1 [nucleoplasm]
(Xenopus tropicalis)
Cby1 [nucleoplasm]
(Mus musculus)
Cby1 [nucleoplasm]
(Rattus norvegicus)
Cby [nucleoplasm]
(Drosophila melanogaster)
grlR [nucleoplasm]
(Dictyostelium discoideum)
CBY1 [nucleoplasm]
(Bos taurus)
CBY1 [nucleoplasm]
(Canis familiaris)
CBY1 [nucleoplasm]
(Gallus gallus)
CBY1 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_056188.1
,
NP_001002880.2
OpenTargets
ENSG00000100211
HPA
ENSG00000100211-CBY1
GeneCards
Q9Y3M2
Ensembl
ENST00000411557
,
ENSP00000216029
,
ENSG00000100211
,
ENSP00000380026
,
ENSP00000412260
,
ENST00000416285
,
ENST00000216029
,
ENSP00000413934
,
ENST00000396811
PRO
Q9Y3M2
Pharos - Targets
Q9Y3M2
PDB
4WRQ
Interactors (34)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63104 YWHAZ
2
YWHAZ [nucleoplasm]
(R-HSA-450469)
YWHAZ [cytosol]
(R-HSA-206099)
0.725
4
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.725
5
UniProt:Q96M91 CFA53
0.675
4
UniProt:Q8IYY4 DZI1L
0.666
4
UniProt:A1XBS5 CBAR1
0.666
4
UniProt:Q15311 RALBP1
1
RALBP1 [cytosol]
(R-HSA-195194)
0.666
4
UniProt:Q99816 TSG101
1
TSG101 [endosome membrane]
(R-HSA-2980549)
0.556
3
UniProt:Q5GJ75 TNFAIP8L3
1
TNFAIP8L3 [cytosol]
(R-HSA-8874462)
0.556
3
UniProt:Q6PF05-3 TTC23L
0.556
3
UniProt:A1XBS5-3 CIBAR1
0.556
3
UniProt:A6NK89 RASFA
0.556
3
UniProt:Q9H8Y8 GORASP2
2
GORASP2 [Golgi membrane]
(R-HSA-2422385)
p-T222,T225-GORASP2 [Golgi membrane]
(R-HSA-2422965)
0.556
3
UniProt:Q96MY7 F161B
0.556
3
UniProt:Q8TBB1 LNX1
1
LNX1 [cytosol]
(R-HSA-8851641)
0.556
3
UniProt:Q9H0I2 ENKD1
0.556
3
UniProt:O95302 FKBP9
1
FKBP9 [cytosol]
(R-HSA-391306)
0.527
2
UniProt:Q04917 YWHAH
1
YWHAH [cytosol]
(R-HSA-1445107)
0.527
2
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.527
2
UniProt:P27348 YWHAQ
1
YWHAQ [cytosol]
(R-HSA-1445116)
0.527
2
UniProt:Q8IWC1 MA7D3
0.508
2
UniProt:Q5VUJ6 LRCH2
0.508
2
UniProt:Q14CB8 ARHGAP19
1
ARHGAP19 [cytosol]
(R-HSA-200767)
0.508
2
UniProt:Q9H2C0 GAN
1
GAN [cytosol]
(R-HSA-976014)
0.508
2
UniProt:Q9UJV9 DDX41
4
DDX41 [nucleoplasm]
(R-HSA-9769601)
DDX41 [cytosol]
(R-HSA-3134807)
K48polyUb-DDX41 [cytosol]
(R-HSA-3134942)
K48polyUb-DDX41 [cytosol]
(R-HSA-3134941)
0.508
2
UniProt:Q14244 MAP7
0.508
2
UniProt:Q6BDS2 BLT3A
0.508
2
UniProt:Q9NXN4 GDAP2
0.508
2
UniProt:Q96N67 DOCK7
1
DOCK7 [cytosol]
(R-HSA-1012970)
0.508
2
UniProt:Q8N5F7 NKAP
1
NKAP [nucleoplasm]
(R-HSA-9769602)
0.508
2
UniProt:Q5SW79 CE170
0.508
2
UniProt:P11908 PRPS2
1
PRPS2 [cytosol]
(R-HSA-58224)
0.508
2
UniProt:Q96BP2 CHCHD1
1
CHCHD1 [mitochondrial inner membrane]
(R-HSA-5368208)
0.508
2
UniProt:O43822 CF410
0.508
2
UniProt:Q7KZI7 MARK2
0.508
2
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