Reactome | CTNNBIP1 [nucleoplasm]

CTNNBIP1 [nucleoplasm]

Stable Identifier

R-HSA-3772388

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

ICAT

Locations in the PathwayBrowser for interactor UniProt:Q4VC12 MSS51

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External Reference Information

External Reference

UniProt:Q9NSA3 CTNNBIP1

Gene Names

CTNNBIP1, ICAT

Chain

chain:1-81

Reference Genes

BioGPS Gene:56998 CTNNBIP1

COSMIC (genes):CTNNBIP1 CTNNBIP1

CTD Gene:56998 CTNNBIP1

dbSNP Gene:56998 CTNNBIP1

ENSEMBL:ENSG00000178585 CTNNBIP1

HGNC:16913 CTNNBIP1

KEGG:hsa:56998 CTNNBIP1

Monarch:56998 CTNNBIP1

NCBI Gene:56998 CTNNBIP1

OMIM:607758 CTNNBIP1

UCSC:Q9NSA3 CTNNBIP1

Reference Transcript

Other Identifiers

11716232_at

11716233_a_at

11716234_s_at

11745524_a_at

16681501

203081_PM_at

203081_at

2395964

2395966

2395967

2395968

2395981

2395982

2395987

2395991

2395999

2396000

2396007

2396008

39171_at

56998

7912283

A_23_P23584

A_33_P3286293

GE62276

GO:0000122

GO:0001658

GO:0002528

GO:0003013

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006355

GO:0008013

GO:0009952

GO:0016055

GO:0030178

GO:0030877

GO:0031333

GO:0032091

GO:0043226

GO:0043433

GO:0045657

GO:0045669

GO:0048662

GO:0060633

GO:0070016

GO:0072201

GO:0090090

GO:1990711

HMNXSV003040978

ILMN_1688103

ILMN_2381168

PH_hs_0022281

TC01002187.hg

TC01005260.hg

g9910389_3p_at

Participates

as a component of

CTNNBIP1:CTNNB1 [nucleoplasm] (Homo sapiens)

as an input of

CTNNBIP1 binds beta-catenin (Homo sapiens)

Inferred To

Ctnnbip1 [nucleoplasm] (Mus musculus)

Ctnnbip1 [nucleoplasm] (Rattus norvegicus)

CTNNBIP1 [nucleoplasm] (Bos taurus)

CTNNBIP1 [nucleoplasm] (Canis familiaris)

CTNNBIP1 [nucleoplasm] (Gallus gallus)

CTNNBIP1 [nucleoplasm] (Sus scrofa)

ctnnbip1 [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_064633.1, NP_001012329.1, XP_016857343.1, XP_016857342.1, XP_016857344.1

OpenTargets

ENSG00000178585

ENSEMBL

ENST00000377263, ENST00000400904, ENSP00000366474, ENST00000377258, ENSP00000366466, ENST00000377256, ENSP00000366468, ENSP00000383696

HPA

ENSG00000178585-CTNNBIP1

PRO

Q9NSA3

Pharos - Targets

Q9NSA3

PDB

1M1E, 1T08, 1LUJ

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35222 CTNNB1	20	CTNNB1 S45A [cytosol] (R-HSA-9663982) CTNNB1 S45F [cytosol] (R-HSA-4791268) CTNNB1 S45C [cytosol] (R-HSA-9663983) CTNNB1 S45Y [cytosol] (R-HSA-9663975) CTNNB1 S45N [cytosol] (R-HSA-9663984) CTNNB1 S45P [cytosol] (R-HSA-4791272) pT41,S45-CTNNB1 S37P [cytosol] (R-HSA-9663981) pT41,S45-CTNNB1 S37F [cytosol] (R-HSA-4839621) CTNNB1 [nucleoplasm] (R-HSA-3451168) CTNNB1 [cytosol] (R-HSA-448839) CTNNB1(1-115) [cytosol] (R-HSA-202930) CTNNB1(116-376) [cytosol] (R-HSA-202950) CTNNB1 [plasma membrane] (R-HSA-9038440) p-S33,S37,T41,S45 CTNNB1 [cytosol] (R-HSA-8942374) p-S37,T41,S45, CTNNB1 [cytosol] (R-HSA-8942369) p-T41,S45 CTNNB1 [cytosol] (R-HSA-8942367) p-S45 CTNNB1 [cytosol] (R-HSA-8942363) p-S552-CTNNB1 [cytosol] (R-HSA-3134933) p-S552-CTNNB1 [nucleoplasm] (R-HSA-3134926) p-Y-CTNNB1 [cytosol] (R-HSA-8876940)	0.955	18
UniProt:P14923 JUP	6	JUP [plasma membrane] (R-HSA-437260) JUP [specific granule lumen] (R-HSA-6799534) JUP [extracellular region] (R-HSA-6806309) JUP [ficolin-1-rich granule lumen] (R-HSA-6801028) JUP [cornified envelope] (R-HSA-8847739) JUP [cytosol] (R-HSA-201598)	0.806	6
UniProt:P25054 APC	20	APC R213* [cytosol] (R-HSA-9666924) APC C1410* [cytosol] (R-HSA-9666925) APC K1310* [cytosol] (R-HSA-9666926) APC R499* [cytosol] (R-HSA-9666927) APC R1450* [cytosol] (R-HSA-5251499) APC G1357* [cytosol] (R-HSA-9666940) APC L1488* [cytosol] (R-HSA-9666941) APC S1400* [cytosol] (R-HSA-9666942) APC S1346* [cytosol] (R-HSA-9666943) APC R405* [cytosol] (R-HSA-9666936) APC S1281* [cytosol] (R-HSA-9666937) APC E1573* [cytosol] (R-HSA-9666938) APC R805* [cytosol] (R-HSA-9666939) APC R1386* [cytosol] (R-HSA-9666932) APC S1327* [cytosol] (R-HSA-9666933) APC E1209* [cytosol] (R-HSA-9666934) APC Q1469* [cytosol] (R-HSA-9666935) APC R564* [cytosol] (R-HSA-9666928) APC E1536* [cytosol] (R-HSA-9666929) APC G1288* [cytosol] (R-HSA-9666930)	0.669	4
UniProt:Q9UL42 PNMA2			0.669	3
UniProt:Q02248 Ctnnb1	14	Ctnnb1 [nucleoplasm] (R-MMU-3451168) Ctnnb1 [cytosol] (R-MMU-448839) Ctnnb1 [cytosol] (R-MMU-202930) Ctnnb1 [cytosol] (R-MMU-202950) Ctnnb1 [nucleoplasm] (R-MMU-9735212) Ctnnb1 [plasma membrane] (R-MMU-9038440) Ctnnb1 [plasma membrane] (R-MMU-9761458) phospho-Ctnnb1 [cytosol] (R-MMU-8942374) beta-catenin [cytosol] (R-MMU-206225) phospho-Ctnnb1 [cytosol] (R-MMU-8942369) phospho-Ctnnb1 [cytosol] (R-MMU-8942367) phospho-Ctnnb1 [cytosol] (R-MMU-8942363) phospho-Ctnnb1 [cytosol] (R-MMU-3134933) phospho-Ctnnb1 [nucleoplasm] (R-MMU-3134926)	0.623	7
UniProt:Q9BRT9 GINS4	1	GINS4 [nucleoplasm] (R-HSA-176963)	0.556	3
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:Q86W54-2 SPATA24			0.556	3
UniProt:P60409 KRTAP10-7	1	KRTAP10-7 [cytosol] (R-HSA-6810279)	0.556	3
UniProt:Q0VD86 INCA1			0.556	3
UniProt:Q7Z4N8 P4HA3	1	P4HA3 [endoplasmic reticulum lumen] (R-HSA-2980915)	0.556	3
UniProt:Q04864 REL	2	REL [cytosol] (R-HSA-1168579) REL [nucleoplasm] (R-HSA-1168585)	0.556	3
UniProt:P26371 KRTAP5-9	1	KRTAP5-9 [cytosol] (R-HSA-6810265)	0.556	3
UniProt:Q8IUG1 KRTAP1-3	1	KRTAP1-3 [cytosol] (R-HSA-6809866)	0.556	3
IntAct:EBI-10171679 386682			0.556	3
UniProt:Q4VC12 MSS51			0.556	3
UniProt:Q8N6Y0 USBP1			0.556	3
UniProt:P10275 AR	4	AR [cytosol] (R-HSA-5618082) AR [nucleoplasm] (R-HSA-446174) monoSUMO1-K386,520-AR [nucleoplasm] (R-HSA-4090320) PolyUb-AR [nucleoplasm] (R-HSA-6782984)	0.532	4
UniProt:Q9UI47 CTNA3			0.527	3
UniProt:P07738 BPGM	1	BPGM [cytosol] (R-HSA-6798334)	0.527	2
UniProt:P14079 TAX			0.488	2

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