SOD1 [mitochondrial intermembrane space]

Stable Identifier
R-HSA-3777082
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Superoxide dismutase [Cu-Zn] ecNumber1.15.1.1/ecNumber, SODC_HUMAN
SOD1 [mitochondrial intermembrane space] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
21393238 Mitochondrial Cu,Zn-superoxide dismutase mediates pulmonary fibrosis by augmenting H2O2 generation

He, C, Murthy, S, McCormick, ML, Spitz, DR, Ryan, AJ, Carter, AB

J. Biol. Chem. 2011
11886899 Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS

Higgins, CM, Jung, C, Ding, H, Xu, Z

J. Neurosci. 2002
External Reference Information
External Reference
Gene Names
SOD1
Chain
initiator methionine:1, chain:2-154
Reference Transcript
Other Identifiers
0000130315
11716935_a_at
11756351_x_at
11757619_x_at
16922102
200642_at
36620_at
3917873
3917874
3917882
3917888
3917890
3917892
3917893
3917894
3917895
3917896
3917897
3917911
6647
8068168
A_14_P105406
A_23_P154840
A_24_P151464
GE79683
GO:0000003
GO:0000187
GO:0000302
GO:0000303
GO:0000902
GO:0001541
GO:0001819
GO:0001890
GO:0001895
GO:0001975
GO:0002262
GO:0002376
GO:0002576
GO:0003013
GO:0003674
GO:0004784
GO:0005507
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005758
GO:0005759
GO:0005764
GO:0005773
GO:0005777
GO:0005829
GO:0005886
GO:0006464
GO:0006629
GO:0006749
GO:0006790
GO:0006801
GO:0006810
GO:0006879
GO:0006950
GO:0006979
GO:0007009
GO:0007010
GO:0007165
GO:0007283
GO:0007566
GO:0007568
GO:0007569
GO:0007605
GO:0007626
GO:0008089
GO:0008090
GO:0008150
GO:0008217
GO:0008219
GO:0008270
GO:0009058
GO:0009408
GO:0009790
GO:0010033
GO:0016192
GO:0016209
GO:0016491
GO:0019226
GO:0019430
GO:0019899
GO:0030141
GO:0030154
GO:0030346
GO:0030705
GO:0031045
GO:0031267
GO:0031410
GO:0031667
GO:0032287
GO:0032839
GO:0032930
GO:0032991
GO:0033081
GO:0034465
GO:0034599
GO:0034641
GO:0035722
GO:0035865
GO:0040007
GO:0040014
GO:0042493
GO:0042542
GO:0042554
GO:0042592
GO:0042802
GO:0043005
GO:0043025
GO:0043065
GO:0043066
GO:0043085
GO:0043087
GO:0043167
GO:0043226
GO:0043524
GO:0044281
GO:0045471
GO:0045541
GO:0045859
GO:0046620
GO:0046677
GO:0046688
GO:0046716
GO:0046872
GO:0048538
GO:0048678
GO:0048856
GO:0050665
GO:0050728
GO:0050766
GO:0050877
GO:0051087
GO:0051881
GO:0055114
GO:0060047
GO:0060052
GO:0060087
GO:0060088
GO:0061024
GO:0070062
GO:0071276
GO:0071318
GO:0072593
GO:0097332
GO:1902177
GO:1904115
HMNXSV003042786
ILMN_1662438
PH_hs_0025933
TC21000111.hg
X02317_at
g4507148_3p_at
Participates
Other forms of this molecule
Interactors (89)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P00441 SOD1  5 0.977 21
 UniProt:O14618 CCS  2 0.744 4
 UniProt:P20029 Hspa5  6 0.688 7
 UniProt:P62191 PSMC1  2 0.666 5
 UniProt:P26339  2 0.625 5
 UniProt:P30044 PRDX5      0.612 10
 UniProt:P16014  2 0.602 6
 UniProt:P29692 EEF1D  1 0.564 3
 IntAct:EBI-25835814 CCSB      0.556 3
 UniProt:Q96MF2 STAC3      0.556 3
 UniProt:Q8WW76 Q8WW76      0.556 3
 UniProt:Q3SY56 SP6      0.556 3
 UniProt:P07951-2 TPM2      0.556 3
 UniProt:Q9H3N1 TMX1      0.556 3
 IntAct:EBI-25850770 CCSB      0.556 3
 UniProt:A4FUJ8 A4FUJ8      0.556 3
 UniProt:Q08209-2 PPP3CA      0.556 3
 UniProt:P48730-2 CSNK1D      0.556 3
 UniProt:Q0P5N6 ARL16      0.556 3
 UniProt:P17980 PSMC3  5 0.556 3
 UniProt:Q15554-4 Q155544      0.556 3
 UniProt:Q13191 CBLB  1 0.556 3
 UniProt:Q9GZS3 WDR61  2 0.556 3
 IntAct:EBI-25934407 CCSB      0.556 3
 UniProt:Q2NKQ1-4 SGSM1      0.556 3
 UniProt:O95777 LSM8  1 0.556 3
 UniProt:P28062-2 PSMB8      0.556 3
 UniProt:Q9NV58 RNF19A  1 0.556 3
 UniProt:Q8NBB4-2 ZSCAN1      0.556 3
 UniProt:P13928 ANXA8      0.556 3
 UniProt:Q13829 TNFAIP1  1 0.556 3
 UniProt:P08865 RPSA  2 0.556 3
 UniProt:P53672 CRBA2      0.556 3
 UniProt:Q5SZD1 CF141      0.556 3
 UniProt:Q15046 KARS1  2 0.556 3
 UniProt:Q16611 BAK1  2 0.556 3
 UniProt:Q96JM7-2 L3MBTL3      0.556 3
 UniProt:Q8NHS9 SPT22      0.556 3
 UniProt:Q8N594 MPND      0.556 3
 UniProt:P43686-2 P436862      0.556 3
 UniProt:Q8TC29 ENKUR      0.556 3
 UniProt:Q9BYU1 PBX4      0.556 3
 UniProt:Q6ZNA4-2 Q6ZNA42      0.556 3
 UniProt:P80217-2 IFI35      0.556 3
 UniProt:Q8WVV9-3 Q8WVV93      0.556 3
 IntAct:EBI-25831191 CCSB      0.556 3
 UniProt:P63010-2 AP2B1      0.556 3
 UniProt:Q96FW1 OTUB1  2 0.556 3
 UniProt:Q13113 PDZ1I      0.556 3
 UniProt:Q9BUL9 RPP25  1 0.556 3
 UniProt:O14713 ITBP1      0.556 3
 IntAct:EBI-25849442 CCSB      0.556 3
 UniProt:Q8N4N3-2 KLHL36      0.556 3
 UniProt:Q6GQQ9-2 Q6GQQ92      0.556 3
 UniProt:Q8TDB4 HUMMR      0.556 3
 UniProt:Q15393 SF3B3  1 0.556 3
 UniProt:Q6DN90-2 Q6DN902      0.556 3
 UniProt:F2Z2M7 F2Z2M7      0.556 3
 UniProt:Q9ULX5 RN112      0.556 3
 IntAct:EBI-25934389 CCSB      0.556 3
 UniProt:P60896 SEM1  2 0.556 3
 UniProt:O95789-4 ZMYM6      0.556 3
 UniProt:Q8N5S9-2 Q8N5S92      0.556 3
 UniProt:Q9Y4H4 GPSM3  1 0.556 3
 IntAct:EBI-25836274 CCSB      0.556 3
 UniProt:O75604-3 USP2      0.556 3
 UniProt:Q92797-2 Q927972      0.556 3
 UniProt:Q8N488 RYBP  1 0.556 3
 UniProt:Q9NVX7-2 Q9NVX72      0.556 3
 UniProt:P09017 HOXC4  1 0.556 3
 UniProt:P62879 GNB2  4 0.556 3
 UniProt:Q2QGD7 ZXDC      0.556 3
 IntAct:EBI-25888984 CCSB      0.556 3
 UniProt:P02671-2 FGA      0.556 3
 UniProt:Q8N448 LNX2      0.556 3
 UniProt:Q96NC0 ZMAT2      0.556 3
 UniProt:P02748 C9  1 0.556 3
 UniProt:Q9BZK7 TBL1XR1  1 0.556 3
 UniProt:Q09028 RBBP4  1 0.556 3
 UniProt:Q9BYZ2 LDHAL6B  1 0.556 3
 UniProt:P07437 TUBB  3 0.556 3
 UniProt:P10415 BCL2  1 0.556 3
 UniProt:P0CG47 UBB  109 0.556 3
 UniProt:P98082 DAB2  3 0.556 3
 UniProt:P07686 HEXB  10 0.527 2
 UniProt:Q99497 PARK7  7 0.527 2
 UniProt:Q8TCX1 DYNC2LI1  2 0.499 3
 UniProt:P04406 GAPDH  1 0.499 3
 UniProt:Q6DN90 IQEC1      0.471 2
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