Reactome | GNE [cytosol]

GNE [cytosol]

Stable Identifier

R-HSA-3781927

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, GLCNE_HUMAN

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External Reference Information

External Reference

UniProt:Q9Y223 GNE

Gene Names

GNE, GLCNE, IBM2

Chain

chain:1-722

Reference Genes

COSMIC (genes):GNE GNE

dbSNP Gene:10020 GNE

ENSEMBL:ENSG00000159921 GNE

Participates

as a component of

GNE hexamer [cytosol] (Homo sapiens)

Other forms of this molecule

GNE V572L [cytosol]

GNE M712T [cytosol]

GNE R263L [cytosol]

GNE R266W [cytosol]

GNE R266Q [cytosol]

GNE A631V [cytosol]

GNE M171V [cytosol]

GNE C303V [cytosol]

Inferred To

GNE [cytosol] (Bos taurus)

GNE [cytosol] (Canis familiaris)

GNE [cytosol] (Danio rerio)

GNE [cytosol] (Gallus gallus)

GNE [cytosol] (Mus musculus)

GNE [cytosol] (Rattus norvegicus)

GNE [cytosol] (Sus scrofa)

GNE [cytosol] (Xenopus tropicalis)

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.666	4
UniProt:P12814 ACTN1	3	ACTN1 [cytosol] (R-HSA-354096) ACTN1 [platelet alpha granule lumen] (R-HSA-349724) ACTN1 [extracellular region] (R-HSA-349722)	0.591	3
UniProt:O43597 SPRY2	8	p-S112,S115-SPRY2 [cytosol] (R-HSA-1295619) SPRY2 [cytosol] (R-HSA-182949) SPRY2 [plasma membrane] (R-HSA-182924) p-S112,S121-SPRY2 [plasma membrane] (R-HSA-934595) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-934555) p-S111,S120-SPRY2 [cytosol] (R-HSA-1295590) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-1295629) p-Y55-SPRY2 [cytosol] (R-HSA-182950)	0.556	3
UniProt:Q969Y2 GTPBP3	1	GTPBP3 [mitochondrial matrix] (R-HSA-6787414)	0.556	3

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