TP53 binds the CDKN1A promoter

Stable Identifier
R-HSA-3786258
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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TP53 (p53), stabilized by ATM-mediated phosphorylation on S15 (Karlseder et al. 1999) binds CDKN1A (p21) promoter (El-Deiry et al. 1993).
Literature References
PubMed ID Title Journal Year
10037601 p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

Karlseder, J, Broccoli, D, Hardy, S, Dai, Y, de Lange, T

Science 1999
8242752 WAF1, a potential mediator of p53 tumor suppression.

Tokino, T, el-Deiry, WS, Kinzler, KW, Vogelstein, B, Lin, D, Mercer, WE, Parsons, R, Trent, JM, Velculescu, VE, Levy, DB

Cell 1993
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