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HARS [cytosol]
Stable Identifier
R-HSA-379554
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Histidyl-tRNA synthetase
Locations in the PathwayBrowser for interactor UniProt:Q9UKE5 TNIK
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
tRNA Aminoacylation (Homo sapiens)
Cytosolic tRNA aminoacylation (Homo sapiens)
histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate (Homo sapiens)
HARS [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12081 HARS1
Gene Names
HARS1, HARS, HRS
Chain
initiator methionine:, chain:2-509
Reference Genes
BioGPS Gene:3035 HARS1
COSMIC (genes):HARS HARS1
CTD Gene:3035 HARS1
dbSNP Gene:3035 HARS1
ENSEMBL:ENSG00000170445 HARS
HGNC:4816 HARS1
Monarch:3035 HARS1
NCBI Gene:3035 HARS1
OMIM:142810 HARS1
UCSC:P12081 HARS1
Reference Transcript
RefSeq:NM_001258040.2 HARS1
RefSeq:NM_002109.5 HARS1
RefSeq:NM_001258042.2 HARS1
RefSeq:NM_001258041.2 HARS1
Other Identifiers
11717139_a_at
11729565_x_at
11746443_a_at
11751324_x_at
17000808
17000813
17117730
17117778
17117784
202042_PM_at
202042_at
2878464
2878465
2878466
2878467
2878468
2878469
2878470
2878471
2878472
2878473
2878475
2878476
2878477
2878478
2878479
2878480
2878482
2878483
2878484
2878485
2878486
2878487
2878488
2878489
2878490
2878491
2878492
2878493
2878494
2878495
2878496
2878497
2878498
2878499
2878500
2878501
2878502
2878503
2878504
2993694
3035
34744_at
3723545
3723546
3723550
3723551
3723554
3760253
3760255
3760256
3760257
3760261
72022_r_at
74823_f_at
7894787
8114625
8114628
A_23_P133227
A_24_P89284
GE542755
GE79010
GO:0003723
GO:0003824
GO:0004812
GO:0004821
GO:0005524
GO:0005737
GO:0005739
GO:0005829
GO:0006399
GO:0006412
GO:0006418
GO:0006427
GO:0006520
GO:0016874
GO:0032543
GO:0042802
GO:0042803
GO:0043226
GO:0140098
HMNXSV003003343
Hs.326464.0.A1_3p_s_at
ILMN_1763523
ILMN_1780991
PH_hs_0004490
TC05001864.hg
TC05001865.hg
X05345_at
Z11518_s_at
g6996013_3p_at
Cross References
ENSEMBL
ENSP00000411511
,
ENST00000457527
,
ENSP00000387893
,
ENSP00000425634
,
ENST00000438307
,
ENST00000504156
,
ENST00000307633
,
ENSP00000304668
OpenTargets
ENSG00000170445
HPA
ENSG00000170445-HARS1
ZINC - Substances
SYHC_HUMAN
ZINC target
P12081
PRO
P12081
Pharos - Targets
P12081
GlyGen
P12081
Orphanet
HARS1
ZINC - Predictions - Purchasable
SYHC_HUMAN
HMDB Protein
HMDBP00645
PDB
5W6M
,
6O76
,
4X5O
,
4PHC
,
1X59
,
2LW7
,
4G85
,
4G84
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P12081 HARS1
1
HARS [cytosol]
(R-HSA-379554)
0.558
2
UniProt:Q9UKE5 TNIK
1
TNIK [cytosol]
(R-HSA-3214889)
0.553
2
UniProt:P49590 HARS2
1
HARS2 [mitochondrial matrix]
(R-HSA-379581)
0.527
2
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