Reactome | EEF1E1 [cytosol]

EEF1E1 [cytosol]

Stable Identifier

R-HSA-379693

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Multisynthetase complex auxiliary component p18, Eukaryotic translation elongation factor 1 epsilon-1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43324 EEF1E1

Gene Names

EEF1E1, AIMP3, P18

Chain

initiator methionine:, chain:2-174

Reference Genes

BioGPS Gene:9521 EEF1E1

COSMIC (genes):EEF1E1 EEF1E1

CTD Gene:9521 EEF1E1

dbSNP Gene:9521 EEF1E1

ENSEMBL:ENSG00000124802 EEF1E1

HGNC:3212 EEF1E1

KEGG:hsa:9521 EEF1E1

Monarch:9521 EEF1E1

NCBI Gene:9521 EEF1E1

OMIM:609206 EEF1E1

UCSC:O43324 EEF1E1

Reference Transcript

Other Identifiers

11737718_a_at

11743582_a_at

204905_PM_s_at

204905_s_at

2500549

2940921

2940923

2940925

2940926

2940927

2940928

2940942

2940943

2940944

2940947

2940948

2940949

2940950

2940951

2940952

40587_s_at

40588_r_at

8123819

9521

A_23_P156842

GE54499

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0006412

GO:0008285

GO:0016020

GO:0017101

GO:0043065

GO:0043226

GO:0043517

GO:1990830

GO:2000774

GO:2001235

HMNXSV003020897

ILMN_1725105

ILMN_2158587

PH_hs_0022204

TC06004111.hg

g4758861_3p_at

Participates

as a component of

Inferred To

EEF1E1 [cytosol] (Bos taurus)

EEF1E1 [cytosol] (Canis familiaris)

EEF1E1 [cytosol] (Sus scrofa)

Ghost homologue of EEF1E1 [cytosol] (Dictyostelium discoideum)

Ghost homologue of EEF1E1 [cytosol] (Gallus gallus)

AIMP3 [cytosol] (Drosophila melanogaster)

Eef1e1 [cytosol] (Mus musculus)

Eef1e1 [cytosol] (Rattus norvegicus)

Cross References

ENSEMBL

ENST00000379715, ENSP00000369038, ENST00000429723, ENSG00000124802, ENSP00000414363

OpenTargets

ENSG00000124802

GeneCards

EEF1E1

HPA

ENSG00000124802-EEF1E1

PRO

O43324

Pharos - Targets

O43324

GlyGen

O43324

PDB

5Y6L, 4BL7, 5BMU, 4BVY, 2UZ8, 4BVX

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P47897 QARS1	2	QARS [cytosol] (R-HSA-379615) QARS [mitochondrial matrix] (R-HSA-379592)	0.527	3
UniProt:P04049 RAF1	20	p-S621-RAF1 S259F [cytosol] (R-HSA-9656124) p-S621-RAF1 S257L [cytosol] (R-HSA-9656121) p-S621-RAF1 P261L [cytosol] (R-HSA-9656106) p-S621-RAF1 N262K [cytosol] (R-HSA-9656101) p-S621-RAF1 P261A [cytosol] (R-HSA-9656103) p-S621-RAF1 P261S [cytosol] (R-HSA-9656113) p-S621-RAF1 S259T [cytosol] (R-HSA-9656130) p-S621-RAF1 P261T [cytosol] (R-HSA-9656115) p-S621-RAF1 P261R [cytosol] (R-HSA-9656110) p-S621-RAF1 S259P [cytosol] (R-HSA-9656127) p-S621-RAF1 T260I [cytosol] (R-HSA-9656136) p-S621-RAF1 T260R [cytosol] (R-HSA-9656139) p-S621-RAF1 V263A [cytosol] (R-HSA-9656148) p-S621-RAF1 R256S [cytosol] (R-HSA-9656119) p-S621-RAF1 T491I [cytosol] (R-HSA-9656143) p-S621-RAF1 D486N [cytosol] (R-HSA-9656088) p-S621-RAF1 S427G [cytosol] (R-HSA-9656134) p-S621-RAF1 L613V [cytosol] (R-HSA-9656098) p-S621-RAF1 G361A [cytosol] (R-HSA-9656092) p-S621-RAF1 G370R [cytosol] (R-HSA-9656094)	0.527	2

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