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Recruitment of mitotic centrosome proteins and complexes
Stable Identifier
R-HSA-380270
Type
Pathway
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
Centrosome maturation (Homo sapiens)
Recruitment of mitotic centrosome proteins and complexes (Homo sapiens)
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The mitotic spindle becomes established once centrosomes have migrated to opposite poles and the nuclear envelope has broken down. During this stage, interphase centrosomes mature into mitotic centrosomes recruiting additional gamma TuRC complexes and acquiring mitosis-associated centrosomal proteins including NuMA, Plk1 and CDK11p58 (reviewed in Schatten 2008; Raynaud-Messina and Merdes 2007).
Literature References
PubMed ID
Title
Journal
Year
18437411
The mammalian centrosome and its functional significance
Schatten, H
Histochem Cell Biol
2008
17178454
Gamma-tubulin complexes and microtubule organization
Raynaud-Messina, B
,
Merdes, A
Curr Opin Cell Biol
2007
Participants
Events
Recruitment of CDK11p58 to the centrosomes
(Homo sapiens)
Recruitment of Plk1 to centrosomes
(Homo sapiens)
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome
(Homo sapiens)
Participates
as an event of
Centrosome maturation (Homo sapiens)
Orthologous Events
Recruitment of mitotic centrosome proteins and complexes (Bos taurus)
Recruitment of mitotic centrosome proteins and complexes (Canis familiaris)
Recruitment of mitotic centrosome proteins and complexes (Gallus gallus)
Recruitment of mitotic centrosome proteins and complexes (Mus musculus)
Recruitment of mitotic centrosome proteins and complexes (Rattus norvegicus)
Recruitment of mitotic centrosome proteins and complexes (Sus scrofa)
Recruitment of mitotic centrosome proteins and complexes (Xenopus tropicalis)
Authored
Matthews, L (2008-11-11)
Reviewed
Merdes, A (2008-11-17)
Created
Matthews, L (2008-11-11)
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