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DNAJB11 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-381040
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
ERdj3, HEDJ
Locations in the PathwayBrowser for interactor UniProt:O75116 ROCK2
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Unfolded Protein Response (UPR) (Homo sapiens)
IRE1alpha activates chaperones (Homo sapiens)
XBP1(S) activates chaperone genes (Homo sapiens)
Expression of DNAJB11 (Homo sapiens)
DNAJB11 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UBS4 DNAJB11
Gene Names
DNAJB11, EDJ, ERJ3, HDJ9, PSEC0121, UNQ537/PRO1080
Chain
signal peptide:1-22, chain:23-358
Reference Genes
BioGPS Gene:51726 DNAJB11
COSMIC (genes):DNAJB11 DNAJB11
CTD Gene:51726 DNAJB11
dbSNP Gene:51726 DNAJB11
ENSEMBL:ENSG00000090520 DNAJB11
ENSEMBL_homo_sapiens_GENE:ENSG00000090520.12 DNAJB11
HGNC:14889 DNAJB11
KEGG Gene (Homo sapiens):51726 DNAJB11
Monarch:51726 DNAJB11
NCBI Gene:51726 DNAJB11
OMIM:611341 DNAJB11
UCSC:Q9UBS4 DNAJB11
Reference Transcript
RefSeq:NM_016306.5 DNAJB11
Other Identifiers
11723655_a_at
16949292
223054_PM_at
223054_at
2656570
2656572
2656573
2656576
2656577
2656578
2656580
2656581
2656582
2656583
2656584
2656585
2656586
2656587
50349_at
51726
8084634
A_14_P115555
A_23_P166899
GE82104
GO:0005102
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005783
GO:0005788
GO:0006457
GO:0016020
GO:0016071
GO:0016556
GO:0030154
GO:0032781
GO:0034663
GO:0043226
GO:0048856
GO:0050768
GO:0051082
GO:0051604
GO:0051787
GO:0101031
HMNXSV003002506
ILMN_1753243
PH_hs_0023768
PH_hs_0040503
TC03001018.hg
g12654614_3p_at
Participates
as an output of
Expression of DNAJB11 (Homo sapiens)
Cross References
RefSeq
NP_057390.1
OpenTargets
ENSG00000090520
GeneCards
Q9UBS4
HPA
ENSG00000090520-DNAJB11
Ensembl
ENSP00000414398
,
ENST00000439351
,
ENST00000265028
,
ENSG00000090520
,
ENSP00000265028
PRO
Q9UBS4
Pharos - Targets
Q9UBS4
Orphanet
27553
Interactors (25)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P11021 HSPA5
6
HSPA5 [extracellular region]
(R-HSA-351322)
HSPA5 [endoplasmic reticulum lumen]
(R-HSA-387190)
HSPA5 [endoplasmic reticulum membrane]
(R-HSA-351315)
HSPA5 [cytosol]
(R-HSA-5252115)
HSPA5 [nucleoplasm]
(R-HSA-5252042)
HSPA5 [lumenal side of endoplasmic reticulum membrane]
(R-HSA-985498)
0.829
5
UniProt:Q71U36 TUBA1A
9
AcK-TUBA1A [cytosol]
(R-HSA-5618312)
Ac K40 TUBA1A [axonemal microtubule]
(R-HSA-5624852)
TUBA1A folding intermediate [cytosol]
(R-HSA-392805)
TUBA1A unfolded [cytosol]
(R-HSA-392767)
L-isoglutamyl polyglycyl-TUBA1A [cytosol]
(R-HSA-8867428)
Polyglutamyl-TUBA1A [cytosol]
(R-HSA-8867408)
TUBA1A(1-450) [cytosol]
(R-HSA-8955577)
TUBA1A [cytosol]
(R-HSA-191689)
TUBA1A [axonemal microtubule]
(R-HSA-5610433)
0.725
4
UniProt:Q8NDZ2 SIMC1
0.659
3
UniProt:Q8ZQQ2 SLRP
0.602
4
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.569
3
UniProt:P02452 COL1A1
20
3x4Hyp-3Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2023648)
3x4Hyp-GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2023667)
GlcGalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2023604)
GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2022999)
3x4Hyp-3Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2023559)
3x4Hyp-GalHyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2023582)
COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-1650777)
3x4Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-1985659)
3x4Hyp-3Hyp-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2022446)
3x4Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2022951)
3x4Hyp-3Hyp-5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-2022954)
5Hyl-COL1A1(23-1464) [endoplasmic reticulum lumen]
(R-HSA-1985663)
Lysyl-pyrrolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396137)
Lysyl-pyrrolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396440)
Lysyl-pyrrolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396471)
Lysyl-pyridinolyl 5-hydroxylysyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396464)
Lysyl-pyridinolyl 4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396068)
Lysyl-pyridinolyl 3,4-Hyp 5-Hyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396388)
Dehydrolysinonorlysyl 4-hydroxyprolyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396315)
Dehydrolysinonorlysyl 4-Hyp 5-Gal-Hyl collagen alpha-1(I) chain [extracellular region]
(R-HSA-2396441)
0.558
3
UniProt:P15516 HTN3
2
HTN3 [extracellular region]
(R-HSA-6807183)
HTN3(20-43) [extracellular region]
(R-HSA-6807136)
0.556
3
UniProt:P21246 PTN
1
PTN [extracellular region]
(R-HSA-201500)
0.553
2
UniProt:Q8IWV7 UBR1
1
UBR1 [cytosol]
(R-HSA-976040)
0.553
2
UniProt:Q9Y5X3 SNX5
2
SNX5 [Golgi membrane]
(R-HSA-434336)
SNX5 [cytoplasmic vesicle membrane]
(R-HSA-434207)
0.547
2
UniProt:Q6PGQ7 BORA
3
p-S252-BORA [cytosol]
(R-HSA-4086411)
p-S252,S497,T501-BORA [cytosol]
(R-HSA-3000330)
BORA [cytosol]
(R-HSA-2562607)
0.527
2
UniProt:Q99470 SDF2
0.527
3
UniProt:Q3ZCM7 TUBB8
3
Polyglycyl-TUBB8 [cytosol]
(R-HSA-8867423)
Polyglutamyl-TUBB8 [cytosol]
(R-HSA-8867387)
TUBB8 [cytosol]
(R-HSA-6805243)
0.527
3
UniProt:Q9HCN8 SDF2L
0.527
3
UniProt:Q4G0X4 KCD21
0.527
3
UniProt:Q8NBX0 SCCPDH
2
SCCPDH [extracellular region]
(R-HSA-8862997)
SCCPDH [platelet alpha granule lumen]
(R-HSA-8862982)
0.527
2
UniProt:Q5JTY5 ZNG1C
0.527
2
UniProt:Q8TB37 NUBPL
1
NUBPL [mitochondrial matrix]
(R-HSA-5689133)
0.527
3
UniProt:O75116 ROCK2
2
ROCK2 [cytosol]
(R-HSA-419058)
Activated ROCK2 [cytosol]
(R-HSA-4687775)
0.527
2
UniProt:P68366 TUBA4A
9
TUBA4A [cytosol]
(R-HSA-191694)
TUBA4A [axonemal microtubule]
(R-HSA-5610443)
TUBA4A [extracellular region]
(R-HSA-350734)
Polyglutamyl-TUBA4A [cytosol]
(R-HSA-8867386)
L-isoglutamyl polyglycyl-TUBA4A [cytosol]
(R-HSA-8867378)
TUBA4A unfolded [cytosol]
(R-HSA-392771)
TUBA4A folding intermediate [cytosol]
(R-HSA-392800)
Ac K40 TUBA4A [axonemal microtubule]
(R-HSA-5624859)
AcK-TUBA4A [cytosol]
(R-HSA-5618318)
0.527
2
UniProt:Q5SVS4 KMCP1
0.527
2
UniProt:P06788 VE7
0.488
2
UniProt:P21860 ERBB3
0.483
2
UniProt:P04578-PRO_0000038427 ENV
0.462
3
UniProt:P04578 env
7
Surface protein gp120 (P04578) [cytosol]
(R-HIV-189269)
Transmembrane protein gp41 (P04578) [cytosol]
(R-HIV-189359)
Glycosylated Envelope glycoprotein gp160 [Golgi membrane]
(R-HIV-3149443)
Envelope glycoprotein gp160 [endoplasmic reticulum membrane]
(R-HIV-189343)
Transmembrane protein gp41 [viral envelope]
(R-HIV-171195)
ENV [viral envelope]
(R-HIV-173439)
Surface protein gp120 [viral envelope]
(R-HIV-171211)
0.462
4
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