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MBTPS2 [Golgi membrane]
Stable Identifier
R-HSA-381131
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
S2P
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Unfolded Protein Response (UPR) (Homo sapiens)
ATF6 (ATF6-alpha) activates chaperones (Homo sapiens)
MBTPS2 (S2P) cleaves ATF6 (ATF6-alpha) (Homo sapiens)
MBTPS2 [Golgi membrane] (Homo sapiens)
ATF6B (ATF6-beta) activates chaperones (Homo sapiens)
MBTPS2 (S2P) cleaves ATF6B (ATF6-beta) (Homo sapiens)
MBTPS2 [Golgi membrane] (Homo sapiens)
CREB3 factors activate genes (Homo sapiens)
MBTPS2 (S2P) cleaves CREB3 (Homo sapiens)
MBTPS2 [Golgi membrane] (Homo sapiens)
MBTPS2 (S2P) cleaves CREB3L1 (Homo sapiens)
MBTPS2 [Golgi membrane] (Homo sapiens)
MBTPS2 (S2P) cleaves CREB3L2 (Homo sapiens)
MBTPS2 [Golgi membrane] (Homo sapiens)
MBTPS2 (S2P) cleaves CREB3L3 (Homo sapiens)
MBTPS2 [Golgi membrane] (Homo sapiens)
MBTPS2 (S2P) cleaves CREB3L4 (Homo sapiens)
MBTPS2 [Golgi membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
S2P hydrolyzes SREBP1A,1C,2 (Homo sapiens)
MBTPS2 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43462 MBTPS2
Gene Names
MBTPS2, S2P
Chain
chain:1-519
Reference Genes
BioGPS Gene:51360 MBTPS2
COSMIC (genes):MBTPS2 MBTPS2
CTD Gene:51360 MBTPS2
dbSNP Gene:51360 MBTPS2
ENSEMBL:ENSG00000012174 MBTPS2
ENSEMBL_homo_sapiens_GENE:ENSG00000012174.12 MBTPS2
HGNC:15455 MBTPS2
KEGG Gene (Homo sapiens):51360 MBTPS2
Monarch:51360 MBTPS2
NCBI Gene:51360 MBTPS2
OMIM:300294 MBTPS2
UCSC:O43462 MBTPS2
Reference Transcript
RefSeq:NM_015884.3 MBTPS2
Other Identifiers
11723207_at
11723208_a_at
17102017
206473_PM_at
206473_at
226760_PM_at
226760_at
31416_at
3971330
3971331
3971332
3971333
3971335
3971336
3971338
3971339
3971345
3971347
3971355
3971356
3971357
3971359
3971360
3971361
44012_at
51360
62564_at
8166382
91300_at
A_23_P114095
GE54155
GE88614
GO:0000139
GO:0000278
GO:0003824
GO:0004222
GO:0005515
GO:0005737
GO:0005794
GO:0006351
GO:0006355
GO:0006508
GO:0006629
GO:0007095
GO:0008202
GO:0008203
GO:0008233
GO:0008237
GO:0016020
GO:0016787
GO:0023052
GO:0030968
GO:0031293
GO:0034976
GO:0036500
GO:0043226
GO:0045540
GO:0045944
GO:0046872
GO:0048856
GO:0051604
GO:0070977
GO:0098772
GO:0140096
GO:0140537
GO:1905897
HMNXSV003054083
Hs.297007.1.A1_3p_at
Hs.297007.1.A1_3p_x_at
ILMN_1798311
ILMN_1860288
PH_hs_0024887
PH_hs_0039207
TC0X000098.hg
TC0X001618.hg
g7706692_3p_at
Other forms of this molecule
MBTPS2 [endoplasmic reticulum membrane]
Inferred To
S2P [Golgi membrane]
(Drosophila melanogaster)
MBTPS2 [Golgi membrane]
(Bos taurus)
MBTPS2 [Golgi membrane]
(Caenorhabditis elegans)
MBTPS2 [Golgi membrane]
(Canis familiaris)
MBTPS2 [Golgi membrane]
(Gallus gallus)
MBTPS2 [Golgi membrane]
(Mus musculus)
MBTPS2 [Golgi membrane]
(Sus scrofa)
mbtps2 [Golgi membrane]
(Danio rerio)
mbtps2 [Golgi membrane]
(Dictyostelium discoideum)
mbtps2 [Golgi membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_056968.1
OpenTargets
ENSG00000012174
GeneCards
O43462
HPA
ENSG00000012174-MBTPS2
Ensembl
ENSP00000368798
,
ENST00000379484
,
ENSG00000012174
PRO
O43462
Pharos - Targets
O43462
Orphanet
18365
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