Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
KLF5 [nucleoplasm]
Stable Identifier
R-HSA-381279
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Krueppel-like factor 5, KLF5_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Adipogenesis (Homo sapiens)
Transcriptional regulation of white adipocyte differentiation (Homo sapiens)
Expression of KLF5 (Homo sapiens)
KLF5 [nucleoplasm] (Homo sapiens)
Expression of PPARG (Homo sapiens)
KLF5 [nucleoplasm] (Homo sapiens)
Transcriptional regulation of granulopoiesis (Homo sapiens)
KLF5 gene expression is enhanced by CEBPA (Homo sapiens)
KLF5 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13887 KLF5
Gene Names
KLF5, BTEB2, CKLF, IKLF
Chain
chain:1-457
Reference Genes
BioGPS Gene:688 KLF5
COSMIC (genes):CKLF KLF5
COSMIC (genes):KLF5 KLF5
CTD Gene:688 KLF5
dbSNP Gene:688 KLF5
ENSEMBL:ENSG00000102554 KLF5
HGNC:6349 KLF5
Monarch:688 KLF5
NCBI Gene:688 KLF5
OMIM:602903 KLF5
UCSC:Q13887 KLF5
Reference Transcript
RefSeq:NM_001730.4 KLF5
RefSeq:NM_001286818.1 KLF5
Other Identifiers
11744572_a_at
11748761_a_at
11748762_x_at
16775364
209211_PM_at
209211_at
209212_PM_s_at
209212_s_at
3493544
3493545
3493546
3493547
3493548
3493549
3493550
3493551
3493552
3493553
3493555
3493557
3493558
3493559
3493560
3493561
3493567
3493570
3493571
3493572
37926_at
47113_at
688
7969414
A_14_P136369
A_23_P53891
A_24_P210406
D14520_at
GE57080
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0001525
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005794
GO:0006355
GO:0006357
GO:0010468
GO:0014816
GO:0014901
GO:0014908
GO:0023052
GO:0030033
GO:0030154
GO:0032534
GO:0035914
GO:0043226
GO:0043231
GO:0043403
GO:0043426
GO:0045600
GO:0045893
GO:0045944
GO:0046872
GO:0048856
GO:0060576
GO:0061586
GO:0099156
GO:0140110
GO:1902895
GO:1990830
GO:1990837
HMNXSV003054396
ILMN_1770293
PH_hs_0031374
TC13000273.hg
g6580834_3p_at
g8272417_3p_a_at
Participates
as an output of
Expression of KLF5 (Homo sapiens)
KLF5 gene expression is enhanced by CEBPA (Homo sapiens)
This entity regulates
Positively
Expression of PPARG
(Homo sapiens)
Cross References
ENSEMBL
ENSP00000366915
,
ENST00000539231
,
ENST00000377687
,
ENSP00000440407
OpenTargets
ENSG00000102554
HPA
ENSG00000102554-KLF5
PRO
Q13887
Pharos - Targets
Q13887
GlyGen
Q13887
PDB
2EBT
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54253 ATX1
0.659
7
UniProt:Q96A83-2 Q96A832
0.556
3
UniProt:Q9UMF0 ICAM5
1
ICAM5 [plasma membrane]
(R-HSA-197684)
0.556
3
UniProt:P46379-2 BAG6
0.556
3
UniProt:Q9BVL2 NUP58
0.556
3
UniProt:O14645 IDLC
0.556
3
UniProt:P28331-2 NDUFS1
0.556
3
UniProt:O14901 KLF11
0.556
3
UniProt:O75190-2 DNAJB6
0.556
3
UniProt:P0CG48 UBC
20
UBC(381-456) [endocytic vesicle membrane]
(R-HSA-939218)
UBC(533-608) [endocytic vesicle membrane]
(R-HSA-939220)
UBC(609-684) [endocytic vesicle membrane]
(R-HSA-939223)
UBC(457-532) [endocytic vesicle membrane]
(R-HSA-939195)
UBC(153-228) [endocytic vesicle membrane]
(R-HSA-939194)
UBC(305-380) [endocytic vesicle membrane]
(R-HSA-939228)
UBC(229-304) [endocytic vesicle membrane]
(R-HSA-939177)
UBC(77-152) [endocytic vesicle membrane]
(R-HSA-939210)
UBC(1-76) [endocytic vesicle membrane]
(R-HSA-939245)
Ub-565-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783166)
Ub-337-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783121)
Ub-185-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783154)
Ub-261-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783028)
Ub-413-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783061)
Ub-109-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783158)
Ub-641-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783182)
Ub-33-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783073)
Ub-489-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783078)
Ub-291-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783193)
Ub-595-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783130)
0.524
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text