Reactome | SMARCC2 [nucleoplasm]

SMARCC2 [nucleoplasm]

Stable Identifier

R-HSA-389263

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

BAF170

Locations in the PathwayBrowser for interactor UniProt:Q86U86 PBRM1

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External Reference Information

External Reference

UniProt:Q8TAQ2 SMARCC2

Gene Names

SMARCC2, BAF170

Chain

chain:1-1214

Reference Genes

BioGPS Gene:6601 SMARCC2

COSMIC (genes):SMARCC2 SMARCC2

CTD Gene:6601 SMARCC2

dbSNP Gene:6601 SMARCC2

ENSEMBL:ENSG00000139613 SMARCC2

HGNC:11105 SMARCC2

KEGG:hsa:6601 SMARCC2

Monarch:6601 SMARCC2

NCBI Gene:6601 SMARCC2

OMIM:601734 SMARCC2

UCSC:Q8TAQ2 SMARCC2

Reference Transcript

Participates

as a member of

SMARCC1,2 [nucleoplasm] (Homo sapiens)

as a component of

as an input of

SMARCC1 and SMARCC2 bind SMARCD1 (Homo sapiens)

Inferred To

swsn-1 [nucleoplasm] (Caenorhabditis elegans)

smarcc2 [nucleoplasm] (Xenopus tropicalis)

Smarcc2 [nucleoplasm] (Mus musculus)

Smarcc2 [nucleoplasm] (Rattus norvegicus)

SWI3 [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of SMARCC2 [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of SMARCC2 [nucleoplasm] (Schizosaccharomyces pombe)

mor [nucleoplasm] (Drosophila melanogaster)

SMARCC2 [nucleoplasm] (Bos taurus)

SMARCC2 [nucleoplasm] (Canis familiaris)

SMARCC2 [nucleoplasm] (Dictyostelium discoideum)

SMARCC2 [nucleoplasm] (Gallus gallus)

SMARCC2 [nucleoplasm] (Saccharomyces cerevisiae)

SMARCC2 [nucleoplasm] (Schizosaccharomyces pombe)

SMARCC2 [nucleoplasm] (Sus scrofa)

Cross References

OpenTargets

ENSG00000139613

ENSEMBL

ENST00000267064, ENSP00000267064, ENSP00000302919, ENSP00000377591, ENST00000347471, ENSG00000139613, ENST00000394023

HPA

ENSG00000139613-SMARCC2

GeneCards

SMARCC2

PRO

Q8TAQ2

Pharos - Targets

Q8TAQ2

GlyGen

Q8TAQ2

Orphanet

SMARCC2

PDB

7VDV, 6KAG, 6LTH, 7Y8R, 6LTJ

Interactors (27)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12824 SMARCB1	1	SMARCB1 [nucleoplasm] (R-HSA-389261)	0.886	16
UniProt:P51532 SMARCA4	1	SMARCA4 [nucleoplasm] (R-HSA-201686)	0.837	20
UniProt:Q96GM5 SMARCD1	1	SMARCD1 [nucleoplasm] (R-HSA-389255)	0.744	9
UniProt:O14497 ARID1A	1	ARID1A [nucleoplasm] (R-HSA-389259)	0.725	8
UniProt:Q969G3 SMARCE1	1	SMARCE1 [nucleoplasm] (R-HSA-389258)	0.725	6
UniProt:Q8NFD5 ARID1B	1	ARID1B [nucleoplasm] (R-HSA-5225635)	0.708	6
UniProt:O96019 ACTL6A	1	ACTL6A [nucleoplasm] (R-HSA-2980912)	0.669	4
UniProt:Q92922 SMARCC1	1	SMARCC1 [nucleoplasm] (R-HSA-389257)	0.643	4
UniProt:Q8WUB8 PHF10	1	PHF10 [nucleoplasm] (R-HSA-9932814)	0.643	5
UniProt:Q6STE5 SMARCD3	1	SMARCD3 [nucleoplasm] (R-HSA-400141)	0.643	4
UniProt:Q92785 DPF2	1	DPF2 [nucleoplasm] (R-HSA-9727509)	0.643	4
UniProt:P51531 SMARCA2	1	SMARCA2 [nucleoplasm] (R-HSA-389256)	0.632	4
UniProt:Q92925 SMARCD2	1	SMARCD2 [nucleoplasm] (R-HSA-5225626)	0.527	4
UniProt:Q9UHA2 S18L2			0.527	4
UniProt:Q8WUZ0 BCL7C	1	BCL7C [nucleoplasm] (R-HSA-9727457)	0.527	4
UniProt:Q68CP9 ARID2	1	ARID2 [nucleoplasm] (R-HSA-5225613)	0.527	3
UniProt:Q86U86 PBRM1	1	PBRM1 [nucleoplasm] (R-HSA-389254)	0.527	3
UniProt:Q9NPI1 BRD7	1	BRD7 [nucleoplasm] (R-HSA-3222092)	0.527	3
UniProt:O75376 NCOR1	2	NCOR1 [nucleoplasm] (R-HSA-442501) NCOR1 [cytosol] (R-HSA-1253310)	0.524	3
UniProt:Q9NYB0 TERF2IP	1	TERF2IP [nucleoplasm] (R-HSA-174873)	0.508	2
UniProt:Q96PV0 SYNGAP1	1	SYNGAP1 [cytosol] (R-HSA-5658217)	0.499	3
UniProt:O75420 GGYF1			0.499	3
UniProt:Q86UE8 TLK2			0.499	3
UniProt:Q9P2D1 CHD7			0.499	4
UniProt:P48431 SOX2	1	SOX2 [nucleoplasm] (R-HSA-452271)	0.483	2
UniProt:P01100 FOS	2	FOS [nucleoplasm] (R-HSA-450216) p-T325,T331,S362,S374-FOS [nucleoplasm] (R-HSA-450283)	0.483	2
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.462	2

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