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Thrombin:Proteinase-activated receptors [plasma membrane]
Stable Identifier
R-HSA-389470
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Thrombin:Proteinase-activated receptors [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Thrombin:Proteinase-activated receptors [plasma membrane] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Thrombin:Proteinase-activated receptors [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Thrombin:Proteinase-activated receptors [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Thrombin:Proteinase-activated receptors [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Proteinase-activated receptors can bind thrombin (Homo sapiens)
Thrombin:Proteinase-activated receptors [plasma membrane] (Homo sapiens)
Participants
components
activated thrombin (factor IIa) [extracellular region]
(Homo sapiens)
Proteinase-activated receptors [plasma membrane]
(Homo sapiens)
Participates
as an output of
Proteinase-activated receptors can bind thrombin (Homo sapiens)
as a member of
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Inferred To
Thrombin:Proteinase-activated receptors [plasma membrane]
(Bos taurus)
Thrombin:Proteinase-activated receptors [plasma membrane]
(Canis familiaris)
Thrombin:Proteinase-activated receptors [plasma membrane]
(Gallus gallus)
Thrombin:Proteinase-activated receptors [plasma membrane]
(Mus musculus)
Thrombin:Proteinase-activated receptors [plasma membrane]
(Rattus norvegicus)
Thrombin:Proteinase-activated receptors [plasma membrane]
(Sus scrofa)
Thrombin:Proteinase-activated receptors [plasma membrane]
(Xenopus tropicalis)
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