FAR2 reduces PalmCoA to HXOL

Stable Identifier
R-HSA-390438
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
palmitoyl-CoA + 2 NADPH + 2 H+ => hexadecanol + 2 NADP+ [FAR2]
ReviewStatus
5/5
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Peroxisomal fatty acyl-CoA reductase 2 (FAR2) catalyzes the reaction of palmitoyl-CoA (PalmCoA) and 2 NADPH + 2 H+ to form hexadecanol (HXOL), CoASH, and 2 NADP+. As judged from mRNA levels, FAR2 is not widely expressed in the body but is abundant in brain (Cheng and Russell 2004).
Literature References
Participants
Participates
Catalyst Activity

oxidoreductase activity of FAR2 [peroxisomal membrane]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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