Reactome | SKIV2L [cytosol]

SKIV2L [cytosol]

Stable Identifier

R-HSA-391294

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Skiv2l

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q15477 SKIC2

Gene Names

SKIC2, DDX13, SKI2W, SKIV2, SKIV2L, W

Chain

chain:1-1246

Reference Genes

BioGPS Gene:6499 SKIC2

COSMIC (genes):SKIV2L SKIC2

CTD Gene:6499 SKIC2

dbSNP Gene:6499 SKIC2

ENSEMBL:ENSG00000204351 SKIV2L

HGNC:10898 SKIC2

KEGG:hsa:6499 SKIC2

Monarch:6499 SKIC2

NCBI Gene:6499 SKIC2

OMIM:600478 SKIC2

UCSC:Q15477 SKIC2

Reference Transcript

RefSeq:NM_006929.4 SKIC2

Other Identifiers

11746839_a_at

11747466_a_at

11753164_a_at

11760381_at

11760614_at

11760615_x_at

17006984

17007029

17028113

17028157

17030923

17035686

17035730

17038418

17040967

17041011

203727_PM_at

203727_at

2902885

2902886

2902887

2902888

2902889

2902890

2902891

2902892

2902893

2902894

2902895

2902896

2902897

2902898

2902899

2902900

2902901

2902902

2902903

2902904

2902905

2902906

2902907

2902908

2902909

2902910

2902911

2902912

2902913

2902914

2902915

2902916

2902917

2902918

2902919

2902920

2902921

2902922

2902923

2902924

2902925

2902926

2902927

2902928

2902929

2902930

2902931

2902932

2902933

2902934

2902936

2902937

2902938

2902939

2902940

2902941

2902942

2902943

2902944

2902945

37998_at

6499

8118367

8118395

8178136

8178164

8179364

8179391

A_14_P103594

A_14_P134852

A_14_P200186

A_14_P200187

A_23_P168080

GE57699

GE58911

GO:0003676

GO:0003723

GO:0003724

GO:0003824

GO:0004386

GO:0005515

GO:0005524

GO:0005634

GO:0005737

GO:0005829

GO:0006401

GO:0016071

GO:0016787

GO:0016887

GO:0034458

GO:0043226

GO:0055087

GO:0070478

GO:0072344

GO:0140098

GO:0140657

HMNXSV003019635

HMNXSV003030766

HMNXSV003047243

ILMN_1666512

PH_hs_0005025

TC06000389.hg

TC6_cox_hap2000083.hg

TC6_dbb_hap3000074.hg

TC6_mcf_hap5000066.hg

TC6_qbl_hap6000075.hg

TC6_ssto_hap7000067.hg

U09877_at

g13787218_3p_at

Participates

as a candidate of

unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)

as a component of

SKI complex [cytosol] (Homo sapiens)

Inferred To

SKIV2L [cytosol] (Dictyostelium discoideum)

SKIV2L [cytosol] (Gallus gallus)

SKIV2L [cytosol] (Mus musculus)

SKIV2L [cytosol] (Saccharomyces cerevisiae)

SKIV2L [cytosol] (Schizosaccharomyces pombe)

skic2 [cytosol] (Xenopus tropicalis)

SKIC2 [cytosol] (Bos taurus)

SKIC2 [cytosol] (Sus scrofa)

Ghost homologue of SKIV2L [cytosol] (Canis familiaris)

Skic2 [cytosol] (Rattus norvegicus)

tst [cytosol] (Drosophila melanogaster)

skih-2 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_008860.4

ENSEMBL

ENSP00000364543, ENSP00000372827, ENSP00000399530, ENST00000421789, ENST00000448219, ENSP00000400626, ENST00000375394, ENST00000429465, ENST00000383336, ENSP00000394400, ENST00000412823, ENSP00000412310

OpenTargets

ENSG00000204351

IntEnz

3.6.4.13

HPA

ENSG00000204351-SKIC2

PRO

Q15477

Pharos - Targets

Q15477

GlyGen

Q15477

Orphanet

SKIC2

PDB

7QE0, 7QDR, 7QDZ, 7QDY, 7QDS

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P54646 PRKAA2	4	PRKAA2 [cytosol] (R-HSA-200405) p-T172-PRKAA2 [cytosol] (R-HSA-200417) p-T172-PRKAA2 [nucleoplasm] (R-HSA-164171) PRKAA2 [nucleoplasm] (R-HSA-163682)	0.556	3
UniProt:P06748 NPM1	11	NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [granular component] (R-HSA-9017702) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.527	2