Reactome | SIPA1 [cytosol]

SIPA1 [cytosol]

Stable Identifier

R-HSA-392495

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Signal-induced proliferation-associated protein 1, SIPA1_HUMAN, SPA1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96FS4 SIPA1

Gene Names

SIPA1, SPA1

Chain

chain:1-1042

Reference Genes

BioGPS Gene:6494 SIPA1

COSMIC (genes):SIPA1 SIPA1

CTD Gene:6494 SIPA1

dbSNP Gene:6494 SIPA1

ENSEMBL:ENSG00000213445 SIPA1

ENSEMBL_homo_sapiens_GENE:ENSG00000213445.10 SIPA1

HGNC:10885 SIPA1

KEGG Gene (Homo sapiens):6494 SIPA1

Monarch:6494 SIPA1

NCBI Gene:6494 SIPA1

OMIM:602180 SIPA1

UCSC:Q96FS4 SIPA1

Reference Transcript

Other Identifiers

11720117_a_at

16727017

204164_PM_at

204164_at

3335466

3335468

3335469

3335470

3335472

3335473

3335474

3335475

3335477

3335478

3335479

3335480

3335481

3335482

3335483

3335484

3335485

3335487

3335489

3335491

3335492

3335493

3335495

3335496

3335497

36843_at

6494

7941311

A_14_P138661

A_23_P127460

GE81674

GO:0002250

GO:0002376

GO:0003382

GO:0005096

GO:0005515

GO:0005634

GO:0005737

GO:0005794

GO:0005829

GO:0005886

GO:0007010

GO:0007155

GO:0007162

GO:0007163

GO:0007165

GO:0012505

GO:0016020

GO:0023052

GO:0030154

GO:0030308

GO:0032991

GO:0035556

GO:0042631

GO:0043226

GO:0045786

GO:0048471

GO:0048856

GO:0051056

GO:0090162

GO:0098772

HMNXSV003002837

HMNXSV003049064

ILMN_1682930

ILMN_2415536

PH_hs_0027562

TC11000637.hg

g5803168_3p_at

Participates

as a member of

Rap1 GTPase-activating proteins [cytosol] (Homo sapiens)

Inferred To

rapgap1 [cytosol] (Dictyostelium discoideum)

SIPA1 [cytosol] (Bos taurus)

SIPA1 [cytosol] (Canis familiaris)

SIPA1 [cytosol] (Dictyostelium discoideum)

SIPA1 [cytosol] (Gallus gallus)

SIPA1 [cytosol] (Sus scrofa)

rapgapB [cytosol] (Dictyostelium discoideum)

Sipa1 [cytosol] (Mus musculus)

Sipa1 [cytosol] (Rattus norvegicus)

sipa-1 [cytosol] (Caenorhabditis elegans)

Homologues of SIPA1 [cytosol] (Dictyostelium discoideum)

sipa1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_006738.3, NP_694985.29, XP_005274246.1, XP_011543516.1

OpenTargets

ENSG00000213445

HPA

ENSG00000213445-SIPA1

GeneCards

Q96FS4

Ensembl

ENST00000534313, ENST00000394224, ENSG00000213445, ENSP00000436269, ENSP00000377771

PRO

Q96FS4

Pharos - Targets

Q96FS4

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38936 CDKN1A	5	p-T145-CDKN1A [cytosol] (R-HSA-198614) p-Y77-CDKN1A [cytosol] (R-HSA-8942601) CDKN1A [cytosol] (R-HSA-182512) CDKN1A [nucleoplasm] (R-HSA-182585) p-S130-CDKN1A [nucleoplasm] (R-HSA-187857)	0.508	2

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