Reactome | TUBA1C unfolded [cytosol]

TUBA1C unfolded [cytosol]

Stable Identifier

R-HSA-392772

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

unfolded alpha tubulin 6

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9BQE3 TUBA1C

Gene Names

TUBA1C, TUBA6

Chain

chain:1-449, chain:1-448

Reference Genes

BioGPS Gene:84790 TUBA1C

COSMIC (genes):TUBA1C TUBA1C

CTD Gene:84790 TUBA1C

dbSNP Gene:84790 TUBA1C

ENSEMBL:ENSG00000167553 TUBA1C

HGNC:20768 TUBA1C

KEGG:hsa:84790 TUBA1C

Monarch:84790 TUBA1C

NCBI Gene:84790 TUBA1C

UCSC:Q9BQE3 TUBA1C

Reference Transcript

RefSeq:NM_032704.4 TUBA1C

Other Identifiers

11756670_x_at

11758282_s_at

209251_PM_x_at

209251_x_at

211750_PM_x_at

211750_x_at

212639_PM_x_at

212639_x_at

2872626

3344242

3413802

3413807

3413809

3413815

3413816

3413817

3413818

3413819

3413821

3413822

3413823

3413824

3413825

3413826

3413828

3413830

3413848

3453740

3453741

3453742

3453743

3453748

3453749

3453844

3453845

3453847

3453848

3453849

7955179

84790

A_23_P128154

A_23_P128161

A_24_P188071

GE83486

GO:0000226

GO:0000278

GO:0003824

GO:0005198

GO:0005200

GO:0005515

GO:0005525

GO:0005634

GO:0005737

GO:0005856

GO:0005874

GO:0005881

GO:0007010

GO:0007017

GO:0015630

GO:0016787

GO:0030705

GO:0031982

GO:0043226

GO:0045121

GO:0046872

GO:0051301

HMNXSV003040281

HMNXSV003046005

ILMN_1742167

PH_hs_0028341

TC12000363.hg

TC12000367.hg

TC12002866.hg

g13436316_3p_s_at

Participates

as a member of

Other forms of this molecule

AcK-TUBA1C [cytosol]

Ac K40 TUBA1C [axonemal microtubule]

TUBA1C folding intermediate [cytosol]

L-isoglutamyl polyglycyl-TUBA1C [cytosol]

Polyglutamyl-TUBA1C [cytosol]

TUBA1C(1-448) [cytosol]

TUBA1C [axonemal microtubule]

TUBA1C [cytosol]

Cross References

RefSeq

NP_116093.1

ENSEMBL

ENSP00000301072, ENST00000301072

OpenTargets

ENSG00000167553

HPA

ENSG00000167553-TUBA1C

PRO

Q9BQE3

Pharos - Targets

Q9BQE3

GlyGen

Q9BQE3

HMDB Protein

HMDBP08595

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08670 VIM	11	Vimentin [lysosomal lumen] (R-HSA-9659977) Vimentin [cytosol] (R-HSA-9646687) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [late endosome lumen] (R-HSA-9660019) VIM [cytosol] (R-HSA-201600) VIM(2-259) [cytosol] (R-HSA-350323) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-429) [cytosol] (R-HSA-350317) VIM(430-466) [cytosol] (R-HSA-350316) VIM(86-466) [cytosol] (R-HSA-350294) VIM(2-85) [cytosol] (R-HSA-350264)	0.556	3
UniProt:Q8N0Z6 TTC5	3	TTC5 [nucleoplasm] (R-HSA-6804264) p-S203-TTC5 [nucleoplasm] (R-HSA-6804261) p-S203,S221-TTC5 [nucleoplasm] (R-HSA-6804259)	0.527	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.527	6
UniProt:P36507 MAP2K2	12	p-S222,S226-MAP2K2 [cytosol] (R-HSA-169292) MAP2K2 [cytosol] (R-HSA-59504) p-S,T-MAP2K2 [cytosol] (R-HSA-109848) MAP2K2 N126D [cytosol] (R-HSA-9652079) MAP2K2 L46F [cytosol] (R-HSA-9652076) MAP2K2 F57C [cytosol] (R-HSA-9652073) MAP2K2 Y134C [cytosol] (R-HSA-9652089) MAP2K2 V35M [cytosol] (R-HSA-9652086) MAP2K2 P128Q [cytosol] (R-HSA-9652082) MAP2K2 C125S [cytosol] (R-HSA-9652070) MAP2K2(11-400) [cytosol] (R-HSA-5211337) MAP2K2(1-10) [cytosol] (R-HSA-5211334)	0.527	3
UniProt:P07437 TUBB	3	TUBB [extracellular region] (R-HSA-380317) TUBB [azurophil granule lumen] (R-HSA-6799370) TUBB [cytosol] (R-HSA-9020816)	0.527	2
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.527	5

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