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FOXC2 [nucleoplasm]
Stable Identifier
R-HSA-3927898
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Forkhead box protein C2, FOXC2_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Gastrulation (Homo sapiens)
Formation of intermediate mesoderm (Homo sapiens)
Expression of LHX1 in intermediate mesoderm (Homo sapiens)
FOXC2 [nucleoplasm] (Homo sapiens)
Expression of OSR1 in intermediate mesoderm (Homo sapiens)
FOXC2 [nucleoplasm] (Homo sapiens)
Formation of paraxial mesoderm (Homo sapiens)
Somitogenesis (Homo sapiens)
Expression of MESP2 in presomitic mesoderm (Homo sapiens)
FOXC2 [nucleoplasm] (Homo sapiens)
Kidney development (Homo sapiens)
Formation of the ureteric bud (Homo sapiens)
Expression of GDNF in metanephric mesenchyme (Homo sapiens)
FOXC2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99958 FOXC2
Gene Names
FOXC2, FKHL14, MFH1
Chain
chain:1-501
Reference Genes
BioGPS Gene:2303 FOXC2
COSMIC (genes):FOXC2 FOXC2
CTD Gene:2303 FOXC2
dbSNP Gene:2303 FOXC2
ENSEMBL:ENSG00000176692 FOXC2
ENSEMBL_homo_sapiens_GENE:ENSG00000176692.8 FOXC2
HGNC:3801 FOXC2
KEGG Gene (Homo sapiens):2303 FOXC2
Monarch:2303 FOXC2
NCBI Gene:2303 FOXC2
OMIM:602402 FOXC2
UCSC:Q99958 FOXC2
Reference Transcript
RefSeq:NM_005251.2 FOXC2
Other Identifiers
11715312_at
16821660
214520_PM_at
214520_at
2303
239058_PM_at
239058_at
31698_at
3672647
3672648
3672649
3672650
3672651
3672652
3672653
3672654
3672655
3672656
3672657
3672658
7997733
A_14_P125820
A_24_P82358
A_33_P3302295
GE61182
GO:0000122
GO:0000785
GO:0000976
GO:0000977
GO:0000978
GO:0000981
GO:0001216
GO:0001228
GO:0001501
GO:0001503
GO:0001568
GO:0001569
GO:0001656
GO:0001657
GO:0001756
GO:0001822
GO:0001945
GO:0001946
GO:0001974
GO:0003007
GO:0003013
GO:0003275
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0006351
GO:0006355
GO:0006357
GO:0007155
GO:0007219
GO:0007498
GO:0007507
GO:0008283
GO:0008286
GO:0009653
GO:0009725
GO:0010595
GO:0012501
GO:0014032
GO:0016604
GO:0023052
GO:0030154
GO:0030198
GO:0030199
GO:0031490
GO:0033630
GO:0035050
GO:0035470
GO:0042060
GO:0042802
GO:0043010
GO:0043226
GO:0043565
GO:0045893
GO:0045944
GO:0046620
GO:0048010
GO:0048341
GO:0048343
GO:0048701
GO:0048703
GO:0048704
GO:0048844
GO:0048856
GO:0048870
GO:0055010
GO:0060038
GO:0072011
GO:0072112
GO:0072144
GO:0090050
GO:0097746
GO:0120163
GO:0140110
GO:1902257
GO:1990837
GO:1990841
HMNXSV003032231
Hs.239571.0.S1_3p_at
Hs.252844.0.A1_3p_at
ILMN_1705201
PH_hs_0025507
TC16000670.hg
Y08223_at
This entity regulates
Negatively
Expression of LHX1 in intermediate mesoderm
(Homo sapiens)
Expression of OSR1 in intermediate mesoderm
(Homo sapiens)
Expression of GDNF in metanephric mesenchyme
(Homo sapiens)
Cross References
RefSeq
NP_005242.1
OpenTargets
ENSG00000176692
GeneCards
Q99958
HPA
ENSG00000176692-FOXC2
Ensembl
ENSP00000497759
,
ENST00000649859
,
ENSG00000176692
PRO
Q99958
Pharos - Targets
Q99958
Orphanet
16065
PDB
6AKP
,
6LBM
,
6O3T
,
6AKO
,
1D5V
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63151 PPP2R2A
2
PPP2R2A [nucleoplasm]
(R-HSA-1564978)
PPP2R2A [cytosol]
(R-HSA-377253)
0.564
2
UniProt:Q9BYR6 KRTAP3-3
1
KRTAP3-3 [cytosol]
(R-HSA-6809859)
0.556
3
UniProt:Q86VP1 TAX1BP1
1
TAX1BP1 [cytosol]
(R-HSA-937346)
0.556
3
UniProt:P14373 TRIM27
2
TRIM27 [nucleoplasm]
(R-HSA-2997690)
TRIM27 [cytosol]
(R-HSA-8851002)
0.556
3
UniProt:Q8N6F8 MET27
0.556
3
UniProt:Q96IQ6 Q96IQ6
0.556
3
UniProt:Q93062 RBPMS
0.556
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:Q99958 FOXC2
1
FOXC2 [nucleoplasm]
(R-HSA-3927898)
0.499
2
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