Reactome | PAX8 [nucleoplasm]

PAX8 [nucleoplasm]

Stable Identifier

R-HSA-3968418

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Paired box protein Pax-8, PAX8_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9UBE0 SAE1

Expand all

External Reference Information

External Reference

UniProt:Q06710 PAX8

Gene Names

PAX8

Chain

chain:1-450

Reference Genes

BioGPS Gene:7849 PAX8

COSMIC (genes):PAX8 PAX8

CTD Gene:7849 PAX8

dbSNP Gene:7849 PAX8

ENSEMBL:ENSG00000125618 PAX8

ENSEMBL_homo_sapiens_GENE:ENSG00000125618.18 PAX8

HGNC:8622 PAX8

KEGG Gene (Homo sapiens):7849 PAX8

Monarch:7849 PAX8

NCBI Gene:7849 PAX8

OMIM:167415 PAX8

UCSC:Q06710 PAX8

Reference Transcript

Other Identifiers

11724660_a_at

11724661_x_at

11724662_a_at

11741652_a_at

121_PM_at

121_at

16902015

207921_PM_x_at

207921_x_at

207923_PM_x_at

207923_x_at

207924_PM_x_at

207924_x_at

209552_PM_at

209552_at

214528_PM_s_at

214528_s_at

221990_PM_at

221990_at

2571626

2571627

2571628

2571629

2571630

2571631

2571632

2571633

2571634

2571635

2571636

2571649

2571654

2571655

2571657

2571658

2571670

2571671

2571673

2571674

2571677

2571708

2571709

2571710

2571711

36869_at

54494_at

7849

8054740

A_23_P210001

A_23_P324916

A_33_P3234809

GE79168

GO:0000785

GO:0000976

GO:0000978

GO:0000981

GO:0001228

GO:0001655

GO:0001656

GO:0001658

GO:0001822

GO:0001823

GO:0003281

GO:0003337

GO:0003677

GO:0003700

GO:0004996

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006351

GO:0006355

GO:0006357

GO:0006575

GO:0006790

GO:0007417

GO:0009653

GO:0010667

GO:0012501

GO:0023052

GO:0030154

GO:0030855

GO:0030878

GO:0038194

GO:0039003

GO:0042472

GO:0042981

GO:0043226

GO:0043565

GO:0045893

GO:0045944

GO:0048793

GO:0048856

GO:0060089

GO:0071371

GO:0071599

GO:0072050

GO:0072073

GO:0072108

GO:0072164

GO:0072207

GO:0072221

GO:0072278

GO:0072284

GO:0072289

GO:0072305

GO:0072307

GO:0090190

GO:0140110

GO:1900212

GO:1900215

GO:1900218

GO:1990837

GO:2000594

GO:2000611

GO:2000612

HMNXSV003019472

Hs.73149.4.S1_3p_at

ILMN_1656563

ILMN_1708534

ILMN_2319292

PH_hs_0038498

TC02002222.hg

X69699_at

g12654464_3p_s_at

g7669541_3p_s_at

Participates

as an output of

Expression of PAX8 in intermediate mesoderm (Homo sapiens)

This entity regulates

Positively

Expression of LHX1 (LIM1) in the nephric duct (Homo sapiens)

Cross References

RefSeq

NP_039246.1, NP_003457.1, NP_054698.1, NP_039247.1

OpenTargets

ENSG00000125618

GeneCards

Q06710

HPA

ENSG00000125618-PAX8

Ensembl

ENSP00000451240, ENSP00000263334, ENSP00000314750, ENST00000468980, ENSP00000263335, ENST00000348715, ENSP00000380768, ENSG00000125618, ENST00000263334, ENST00000263335, ENSP00000395498, ENST00000397647, ENST00000429538

PRO

Q06710

Pharos - Targets

Q06710

Orphanet

16614

PDB

2K27

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q00526 CDK3			0.556	3
UniProt:O75177-5 SS18L1			0.556	3
UniProt:P31273 HOXC8	1	HOXC8 [nucleoplasm] (R-HSA-3222311)	0.556	3
UniProt:P31274 HXC9			0.556	3
UniProt:O75603 GCM2			0.556	3
UniProt:Q9UBE0 SAE1	1	SAE1 [nucleoplasm] (R-HSA-947697)	0.556	3
UniProt:Q17RB8 LONRF1	1	LONRF1 [cytosol] (R-HSA-8850905)	0.556	3
UniProt:Q08117-2 TLE5			0.556	3
UniProt:Q8TEW6 DOK4	1	DOK4 [cytosol] (R-HSA-8847701)	0.556	3
UniProt:Q9NRX5 SERINC1	1	SERINC1 [plasma membrane] (R-HSA-5215963)	0.524	2
UniProt:O00712 NFIB	1	NFIB [nucleoplasm] (R-HSA-60136)	0.471	2
UniProt:Q12857 NFIA	1	NFIA [nucleoplasm] (R-HSA-60134)	0.471	2