LARG binds plexin B1

Stable Identifier
R-HSA-398185
Type
Reaction
Species
Homo sapiens
Compartment
plasma membrane, cytosol
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LARG binds plexin B1
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LARG binds plexin-B1, a transmembrane receptor for the semaphorin Sema4D. Binding of Sema4D to plexin-B1 stimulates RhoA activation.

Literature References
PubMed ID Title Journal Year
12123608 Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology

Offermanns, S, Behrens, J, Kuner, R, Swiercz, JM

Neuron 2002
Participants
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Output
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as an event of
Orthologous Events
LARG binds plexin B1 (Caenorhabditis elegans)
LARG binds plexin B1 (Canis familiaris)
LARG binds plexin B1 (Danio rerio)
LARG binds plexin B1 (Drosophila melanogaster)
LARG binds plexin B1 (Gallus gallus)
LARG binds plexin B1 (Mus musculus)
LARG binds plexin B1 (Rattus norvegicus)
LARG binds plexin B1 (Sus scrofa)
LARG binds plexin B1 (Xenopus tropicalis)
Authored
Jupe, S  (2009-03-18)
Reviewed
Akkerman, JW  (2009-06-03)
Created
Jupe, S  (2009-03-18)
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