Reactome | PLXNA4 [plasma membrane]

PLXNA4 [plasma membrane]

Stable Identifier

R-HSA-399736

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Plexin-A4, PLXA4_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9HCM2 PLXNA4

Gene Names

PLXNA4, KIAA1550, PLXNA4A, PLXNA4B, UNQ2820/PRO34003

Chain

signal peptide:1-23, chain:24-1894

Reference Genes

BioGPS Gene:91584 Q9HCM23

COSMIC (genes):PLXNA4 PLXNA4

CTD Gene:91584 Q9HCM23

dbSNP Gene:91584 PLXNA4

ENSEMBL:ENSG00000221866 PLXNA4

HGNC:9102 Q9HCM23

KEGG:hsa:91584 Q9HCM23

Monarch:91584 Q9HCM23

NCBI Gene:91584 Q9HCM23

OMIM:604280 Q9HCM23

UCSC:Q9HCM2 Q9HCM23

Reference Transcript

Participates

as an output of

PLXNA4 gene expression is stimulated by FOXO6 (Homo sapiens)

as a member of

Other forms of this molecule

p-Y-PLXNA4 [plasma membrane]

Inferred To

Plxna4 [plasma membrane] (Mus musculus)

Plxna4 [plasma membrane] (Rattus norvegicus)

PLXNA4 [plasma membrane] (Bos taurus)

PLXNA4 [plasma membrane] (Canis familiaris)

PLXNA4 [plasma membrane] (Gallus gallus)

PLXNA4 [plasma membrane] (Sus scrofa)

plx-1 [plasma membrane] (Caenorhabditis elegans)

plxna4 [plasma membrane] (Danio rerio)

plxna4 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_054215284.1, XP_054215283.1, XP_054215287.1, NP_001099013.1, XP_047276975.1, NP_001380826.1, NP_065962.1, NP_861440.2, XP_006716234.1, XP_047276973.1, XP_005250743.1

OpenTargets

ENSG00000221866

ENSEMBL

ENSP00000323194, ENSG00000221866, ENSP00000367800, ENST00000378539, ENST00000359827, ENSP00000352882, ENSP00000392772, ENST00000423507, ENST00000321063

HPA

ENSG00000221866-PLXNA4

GeneCards

PLXNA4

PRO

Q9HCM2

Pharos - Targets

Q9HCM2

GlyGen

Q9HCM2

PDB

4E74

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95825 QORL1			0.564	2
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.558	2
UniProt:Q06481 APLP2	4	APLP2 [endoplasmic reticulum lumen] (R-HSA-8956784) p-APLP2 [endoplasmic reticulum lumen] (R-HSA-8956977) APLP2 [platelet alpha granule membrane] (R-HSA-8848898) APLP2 [plasma membrane] (R-HSA-8848902)	0.558	2