Reactome | NPAS2 [cytosol]

NPAS2 [cytosol]

Stable Identifier

R-HSA-400314

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Neuronal PAS domain-containing protein 2, NPAS2_HUMAN

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Locations in the PathwayBrowser for interactor UniProt:Q9WTL8 Arntl

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External Reference Information

External Reference

UniProt:Q99743 NPAS2

Gene Names

NPAS2, BHLHE9, MOP4, PASD4

Chain

chain:1-824

Reference Genes

BioGPS Gene:4862 NPAS2

COSMIC (genes):NPAS2 NPAS2

CTD Gene:4862 NPAS2

dbSNP Gene:4862 NPAS2

ENSEMBL:ENSG00000170485 NPAS2

HGNC:7895 NPAS2

KEGG:hsa:4862 NPAS2

Monarch:4862 NPAS2

NCBI Gene:4862 NPAS2

OMIM:603347 NPAS2

UCSC:Q99743 NPAS2

Reference Transcript

RefSeq:NM_002518.3 NPAS2

Other Identifiers

11729275_a_at

11749671_a_at

11754774_s_at

11754812_a_at

16883498

205459_PM_s_at

205459_s_at

205460_PM_at

205460_at

213462_PM_at

213462_at

2496402

2496406

2496423

2496435

2496436

2496440

2496446

2496448

2496449

2496455

2496456

2496457

2496458

2496459

2496460

2496461

2496463

2496464

2496465

2496466

2496467

2496469

2496471

2496475

2496480

2496481

2496482

2496483

2496484

2496485

2496486

2496487

2496488

2496489

2496490

2496491

2496492

2496493

2496494

2496495

2496496

2496497

2496498

2496499

2496500

2496501

2496502

2496503

2496504

2496505

2496508

2496509

2496510

2496511

2496513

2496514

2496515

2496516

2496517

39548_PM_at

39548_at

39549_PM_at

39549_at

4862

4919381_3p_s_at

8043909

A_23_P218597

A_23_P415984

GE59422

GE83339

GE846509

GO:0000785

GO:0000978

GO:0000981

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0005737

GO:0005829

GO:0006355

GO:0006357

GO:0006974

GO:0007417

GO:0009410

GO:0032922

GO:0043226

GO:0045739

GO:0045893

GO:0046872

GO:0046983

GO:0048511

GO:0048856

GO:0051775

GO:0051879

GO:0140110

GO:1990513

GO:1990837

GO:2000987

HMNXSV003000203

Hs.296355.0.S1_3p_s_at

ILMN_1765558

PH_hs_0032652

TC02000611.hg

U77970_at

g4505428_3p_s_at

Participates

as an output of

Expression of NPAS2 (Homo sapiens)

as a member of

CLOCK,NPAS2 [cytosol] (Homo sapiens)

Other forms of this molecule

p-S-NPAS2 [nucleoplasm]

Cross References

RefSeq

NP_002509.2

ENSEMBL

ENST00000335681, ENSP00000338283

OpenTargets

ENSG00000170485

HPA

ENSG00000170485-NPAS2

PRO

Q99743

Pharos - Targets

Q99743

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8WYA1-3 BMAL2			0.743	10
UniProt:O00327-8 BMAL1			0.743	10
UniProt:O00327 ARNTL	3	ARNTL [nucleoplasm] (R-HSA-9634872) ARNTL [cytosol] (R-HSA-400353) p-S-ARNTL [nucleoplasm] (R-HSA-421312)	0.632	4
UniProt:P22607 FGFR3	20	FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 805fs*141 [plasma membrane] (R-HSA-1614387) p-6Y-FGFR3 A391E [plasma membrane] (R-HSA-2065835) p-6Y-FGFR3 K650T [plasma membrane] (R-HSA-2032966) p-6Y-FGFR3 G382D [plasma membrane] (R-HSA-2032950) p-6Y-FGFR3 G380R [plasma membrane] (R-HSA-2032946) p-6Y-FGFR3 K650M [plasma membrane] (R-HSA-2032959)	0.556	3
UniProt:O43639 NCK2	1	NCK2 [cytosol] (R-HSA-204885)	0.556	6
UniProt:Q9Y649 Q9Y649			0.556	3
UniProt:Q0VD86 INCA1			0.556	3
UniProt:Q9NP55 BPIFA1	1	BPIFA1 [extracellular region] (R-HSA-6809280)	0.556	3
UniProt:Q96IV0 NGLY1	1	NGLY1 [cytosol] (R-HSA-8850591)	0.556	3
UniProt:Q5T6F2 UBAP2			0.556	3
UniProt:Q14957 GRIN2C	3	GRIN2C [plasma membrane] (R-HSA-419560) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761) p-Y-GRIN2C [plasma membrane] (R-HSA-9612189)	0.556	3
UniProt:Q9WTL8 Arntl	4	Arntl [nucleoplasm] (R-MMU-9769624) Bmal1 [nucleoplasm] (R-MMU-9634872) Arntl [cytosol] (R-MMU-508660) p-S-Arntl [nucleoplasm] (R-MMU-508690)	0.553	2
UniProt:P97784 Cry1	4	ub-p-Cry1 [nucleoplasm] (R-MMU-517961) p-Cry1 [nucleoplasm] (R-MMU-508662) p-Cry1 [cytosol] (R-MMU-508644) Cry1 [cytosol] (R-MMU-508637)	0.553	2

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