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p-S-CRY1 [nucleoplasm]
Stable Identifier
R-HSA-400340
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
p-CRY1, Phosphorylated Cryptochrome-1, CRY1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Circadian Clock (Homo sapiens)
CRY proteins are ubiquitinylated (Homo sapiens)
FBXL3:CRY [nucleoplasm] (Homo sapiens)
p-CRY1,p-CRY2 [nucleoplasm] (Homo sapiens)
p-S-CRY1 [nucleoplasm] (Homo sapiens)
CRY:PER heterodimer binds the BMAL1:CLOCK/NPAS2 heterodimer (Homo sapiens)
BMAL1:CLOCK,NPAS2:CRY:PER [nucleoplasm] (Homo sapiens)
p-CRY:p-PER:Kinase [nucleoplasm] (Homo sapiens)
p-CRY1,p-CRY2 [nucleoplasm] (Homo sapiens)
p-S-CRY1 [nucleoplasm] (Homo sapiens)
p-CRY:p-PER:Kinase [nucleoplasm] (Homo sapiens)
p-CRY1,p-CRY2 [nucleoplasm] (Homo sapiens)
p-S-CRY1 [nucleoplasm] (Homo sapiens)
CRY:PER:Kinase complex translocates to the nucleus (Homo sapiens)
p-CRY:p-PER:Kinase [nucleoplasm] (Homo sapiens)
p-CRY1,p-CRY2 [nucleoplasm] (Homo sapiens)
p-S-CRY1 [nucleoplasm] (Homo sapiens)
FBXL3 binds phosphorylated CRY proteins (Homo sapiens)
FBXL3:CRY [nucleoplasm] (Homo sapiens)
p-CRY1,p-CRY2 [nucleoplasm] (Homo sapiens)
p-S-CRY1 [nucleoplasm] (Homo sapiens)
p-CRY1,p-CRY2 [nucleoplasm] (Homo sapiens)
p-S-CRY1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q16526 CRY1
Gene Names
CRY1, PHLL1
Chain
chain:1-586
Reference Genes
BioGPS Gene:1407 CRY1
COSMIC (genes):CRY1 CRY1
CTD Gene:1407 CRY1
dbSNP Gene:1407 CRY1
ENSEMBL:ENSG00000008405 CRY1
HGNC:2384 CRY1
Monarch:1407 CRY1
NCBI Gene:1407 CRY1
OMIM:601933 CRY1
UCSC:Q16526 CRY1
Reference Transcript
RefSeq:NM_004075.4 CRY1
Other Identifiers
11723709_a_at
1407
16769622
209674_PM_at
209674_at
3469867
3469868
3469869
3469870
3469871
3469873
3469874
3469875
3469876
3469877
3469878
3469879
3469880
3469881
3469882
3469883
3469886
3469887
3469890
3469894
3469895
3469896
3469900
3469904
3469905
3469906
3469907
38148_at
7966052
A_23_P36665
A_24_P407235
D83702_at
GE57335
GO:0000122
GO:0000166
GO:0003677
GO:0003690
GO:0003824
GO:0005515
GO:0005634
GO:0005737
GO:0005739
GO:0005975
GO:0006094
GO:0006111
GO:0006355
GO:0007623
GO:0009416
GO:0009785
GO:0009881
GO:0009882
GO:0014823
GO:0016829
GO:0016922
GO:0019900
GO:0019901
GO:0019902
GO:0019915
GO:0031397
GO:0031398
GO:0032868
GO:0032922
GO:0033762
GO:0042593
GO:0042752
GO:0042754
GO:0042770
GO:0042826
GO:0043153
GO:0043226
GO:0045721
GO:0045722
GO:0045744
GO:0045892
GO:0048511
GO:0060089
GO:0070888
GO:0071949
GO:0140297
GO:2000001
GO:2000323
GO:2000850
HMNXSV003004814
ILMN_1760593
ILMN_2202637
PH_hs_0009136
TC12001925.hg
g1304106_3p_at
Participates
as a member of
p-CRY1,p-CRY2 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
Ub-p-S-CRY1 [nucleoplasm]
CRY1 [cytosol]
p-S-CRY1 [cytosol]
Modified Residues
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
Guide to Pharmacology - Targets
2876
ENSEMBL
ENSP00000008527
,
ENST00000008527
OpenTargets
ENSG00000008405
HPA
ENSG00000008405-CRY1
PRO
Q16526
Pharos - Targets
Q16526
HMDB Protein
HMDBP02737
Interactors (14)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P49674 CSNK1E
2
CSNK1E [cytosol]
(R-HSA-205877)
CSNK1E [nucleoplasm]
(R-HSA-421306)
0.788
7
UniProt:Q13616 CUL1
3
CUL1 [cytosol]
(R-HSA-174230)
CUL1 [nucleoplasm]
(R-HSA-187551)
G76-NEDD8-K720-CUL1 [cytosol]
(R-HSA-8952519)
0.643
3
UniProt:Q9UKT7 FBXL3
2
FBXL3 [nucleoplasm]
(R-HSA-400380)
FBXL3 [cytosol]
(R-HSA-391289)
0.643
5
UniProt:O15534 PER1
4
p-S-PER1 [cytosol]
(R-HSA-400310)
p-S-PER1 [nucleoplasm]
(R-HSA-3325590)
PER1 [cytosol]
(R-HSA-400373)
Ub-p-S-PER1 [cytosol]
(R-HSA-517831)
0.564
3
UniProt:O15162 PLS1
0.553
2
UniProt:Q8WW24 TEKT4
0.527
2
UniProt:O54943 Per2
4
ub-p-Per2 [cytosol]
(R-MMU-517951)
p-Per2 [nucleoplasm]
(R-MMU-508610)
p-Per2 [cytosol]
(R-MMU-508728)
Per2 [cytosol]
(R-MMU-508621)
0.527
2
UniProt:Q15274 QPRT
1
QPRT [cytosol]
(R-HSA-197212)
0.527
2
UniProt:P48730 CSNK1D
3
CSNK1D [nucleoplasm]
(R-HSA-421305)
CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5685717)
CSNK1D [cytosol]
(R-HSA-380315)
0.527
3
UniProt:Q49AN0 CRY2
4
p-S-CRY2 [cytosol]
(R-HSA-400305)
p-S-CRY2 [nucleoplasm]
(R-HSA-400328)
CRY2 [cytosol]
(R-HSA-400255)
Ub-p-S-CRY2 [nucleoplasm]
(R-HSA-517935)
0.527
3
UniProt:O15516 CLOCK
3
p-S-CLOCK [nucleoplasm]
(R-HSA-421310)
CLOCK [cytosol]
(R-HSA-400392)
CLOCK [nucleoplasm]
(R-HSA-879828)
0.527
3
UniProt:P63208 SKP1
2
SKP1 [cytosol]
(R-HSA-174150)
SKP1 [nucleoplasm]
(R-HSA-187538)
0.527
4
UniProt:Q9WTL8 Arntl
4
Arntl [nucleoplasm]
(R-MMU-9769624)
Bmal1 [nucleoplasm]
(R-MMU-9634872)
Arntl [cytosol]
(R-MMU-508660)
p-S-Arntl [nucleoplasm]
(R-MMU-508690)
0.527
4
UniProt:O14744 PRMT5
3
PRMT5 [cytosol]
(R-HSA-191876)
PRMT5 [nucleoplasm]
(R-HSA-5205609)
p-Y297,304,307-PRMT5 [nucleoplasm]
(R-HSA-5211300)
0.499
3
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