BMAL1:CLOCK,NPAS2 [cytosol]

Stable Identifier
R-HSA-400360
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Synonyms
ARNTL:CLOCK,NPAS2
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General
BMAL1 (ARNTL) contains both a nuclear localization signal and a nuclear export signal. The shuttling of BMAL1 between the nucleus and cytoplasm is important for transactivation by BMAL1:CLOCK/NPAS2 and degradation of BMAL1:CLOCK/NPAS2. BMAL1 initially forms a heterodimer with CLOCK or NPAS2 in the cytosol. The heterodimer is then phosphorylated and translocated into the nucleus.
Participants
components
Participates
as a component of
as an input of
as an output of
Inferred From
Bmal1:Clock,Npas2 [cytosol] (Mus musculus)
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