Reactome | SUMOylation of DAXX with SUMO1

SUMOylation of DAXX with SUMO1

Stable Identifier

R-HSA-4085992

Type

Reaction [transition]

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

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DAXX is SUMOylated at lysine-630 and lysine-631 with SUMO1 (Jang et al. 2002, Lalioti et al. 2002, Lin et al. 2006). SUMOylation of DAXX does not prevent it from localizing to PML oncogenic domains.

Literature References

PubMed ID	Title	Journal	Year
11842083	The insulin-sensitive glucose transporter, GLUT4, interacts physically with Daxx. Two proteins with capacity to bind Ubc9 and conjugated to SUMO1 Sandoval, IV, Lalioti, VS, Vergarajauregui, S, Pulido, D	J. Biol. Chem.	2002
12150977	Modification of Daxx by small ubiquitin-related modifier-1 Kim, E, Jang, MS, Ryu, SW	Biochem. Biophys. Res. Commun.	2002
17081986	Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors Shih, HM, Hung, CC, Chen, YC, Chang, CC, Lin, TP, Chang, KS, Jeng, JC, Chao, TT, Hwang, MJ, Lin, DY, Kuo, HY, Suen, CS, Fang, HI, Ho, CC, Maul, GG, Huang, YS	Mol. Cell	2006