PIAS1,3 SUMOylate NRIP1 with SUMO1

Stable Identifier
R-HSA-4086036
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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PIAS1,3 SUMOylate NRIP1 with SUMO1
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PIAS1,3 SUMOylate NRIP1 (RIP140) at lysine 756 and lysine-1154 with SUMO1 (Rytinki et al. 2008). SUMOylation enhances transcription repression by NRIP1.
Literature References
PubMed ID Title Journal Year
18211901 SUMOylation modulates the transcription repressor function of RIP140

Palvimo, JJ, Rytinki, MM

J. Biol. Chem. 2008
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Output
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as an event of
Catalyst Activity

SUMO transferase activity of PIAS1,3 [nucleoplasm]

Physical Entity
PIAS1,3 [nucleoplasm] (Homo sapiens)
Activity
SUMO transferase activity (GO:0019789)
Orthologous Events
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Bos taurus)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Gallus gallus)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Mus musculus)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Rattus norvegicus)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Sus scrofa)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Xenopus tropicalis)
Authored
May, B  (2013-08-05)
Reviewed
Niskanen, E  (2018-05-09)
Niskanen, E  (2018-08-08)
Created
May, B  (2013-08-07)
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